ADHD Unrelated to Dopamine Dysfunction

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Research from the University of Cambridge finds that "dopamine dysregulation per se is unlikely to be the primary cause underlying attention deficit/hyperactivity disorder pathology...

FDA Applies Uneven Standards to New Drugs’ Safety and Efficacy

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A study in the Journal of the American Medical Association finds that, although "many patients and physicians assume that the safety and effectiveness of...

Pediatric Drugs: More Illness, But Less Research

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An international team of researchers identified all drug trials registered in ClinicalTrials.gov between 2006 and 2011 and tracked the resulting publications, finding that although...

Authorities Ignoring Deaths, Forced Electroshock in Irish Mental Health System

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An internal government investigation found that authorities did not investigate 50% of deaths that occurred inside mental health services in Ireland, reports the Irish...

Unpublished Trials Reveal Antidepressant Provides Little Benefit For Depression or Anxiety

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Upon reviewing all of GlaxoSmithKline's data from both published and unpublished trials of the antidepressant paroxetine, researchers found the drug provided almost no benefits...

Both Pharmacotherapy and Psychotherapy Effect Sizes Small

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In a review of 852 trials of pharmacotherapies and psychotherapies for major psychiatric disorders, involving 137,126 patients, an international team of researchers found that...

Cortisol Levels Increased in Youth at Risk for Psychosis

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Researchers from Columbia University and the Institute of Neurosciences in Barcelona assessed cortisol levels in 33 patients at clinical high risk of psychosis. Cortisol...

Compulsory Supervision Does Not Reduce Hospital Re-Admissions

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A study of 442 individuals discharged from a U.K. hospital, published today in The Lancet, finds that the rate of readmission after 12 months...

SSRIs Impair Learning From Negative Feedback

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A study comparing the effects on cognition of major depression (MDD) vs. SSRIs finds that healthy subjects learn significantly better from positive feedback than...

Europe Issues Policy on Access to Clinical Trial Data, Criticisms Continue

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The European Medicines Agency has announced in a press release its final policies on the open publication of data from clinical trials. Ed Silverman...

Antidepressant is Toxic to Fungus

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Zoloft isn't just for depression any more; it also kills fungal meningitis. Researchers from Texas A&M find that "The problem for many current antifungal...

Robot Bullies Rats into Depression to Test Antidepressant Medication

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Japanese engineers have devised a robotic rat that bullies laboratory rats into a state of depression, creating a model of human depression they deem...

Grandmother Murders old Friend: Court Accepts SSRI as a Cause

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Based on a psychiatrist's recommendation that the effects of citalopram (Celexa) had contributed to a 61 year-old grandmother's lethal bludgeoning of her friend of...

J&J Gets $257 Million Risperdal Verdict Thrown Out in Louisiana

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A Louisiana appeals court has thrown out a $257 million verdict which held Johnson & Johnson liable for deceptive practices in marketing its antipsychotic...

Fish Exposed to Prozac Exhibit Significantly Altered Behavior

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Concentrations of Prozac as low as 1 microgram per liter (Οg/L), a concentration that has been found in many freshwater environments, were found to significantly...

Illinois Allows Psychologists to Prescribe Drugs

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The American Psychological Association is lauding a new Illinois law allowing certain types of psychologists to prescribe psychiatric medications. “This is a landmark moment...

Conflict of Interest Disclosure Far Less Likely in Psychiatric Journals

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A review of 285 review articles from 10 top psychiatric and 2 general medicine journals finds that reviews in psychiatric journals were far less...

Childhood Trauma Predicts Risk of Violence in Psychosis

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A study published in the Journal of Psychiatric Research finds the strongest association between a history of childhood trauma and the risk of violence...

Convicted Murderer Blames Chantix; Appeals Judge’s Refusal to Subpoena Pfizer

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Army Pfc. George D.B. MacDonald, convicted in 2009 of stabbing and slashed a sleeping recruit whom he did not know, is appealing his judge's...

Global Pharmaceutical Industry Fined $11 Billion in Three Years

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Although the global pharmaceutical industry racked up $11 billion in fines in the last three years, "Companies might well view such fines as a...

Excessive Mood & Behavior Arousal in Juveniles Treated with Antidepressants

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In a study of 6,767 reports of antidepressant trials in juveniles treated for depressive and anxiety disorders, the risk of psychopathological behavioral or mood...

Media and Public Frequently Exaggerate Significance of Behavioral Genetics Findings

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Other studies have shown that abstracts and press releases often mislead journalists about the significance of findings in behavioral genetics; but a new study...

How to Involve Youth in Their Own Mental Health Care

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Clinicians play a key role in empowering adolescents and their parents to make decisions about their mental health treatment.

Tension Over Clinical Trial Data Disclosure Escalates

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Pharmalot reviews the escalating tension over clinical trial data disclosure. The PhRMA trade group has come out in opposition to AllTrials, a petition drive...

Bipartisan Agreement on Mental Health Treatment

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The New York Times on Obama's $235 million initiative: "Mental health unites lawmakers Republican and Democrat, urban and rural, even those with safe seats...