Benzodiazepines

I am still trying to reconcile what these chemicals are capable of, how the urge can morph into an action, how we maybe just don’t understand suicide all that well. For me, the suffering was so intense it was too painful to stay alive. I understand how my friends felt in their last moments.

After long-term use, most people are going to have serious symptoms when stopping SSRIs. Many people are going to have transient, mild to moderate difficulty and some are going to end up falling down the akathisia rabbit hole. That is a long, difficult drop.

A large study of the population in Taiwan reveals that long-term use of benzodiazepine drugs, commonly prescribed for anxiety, significantly increases the risk for brain, colorectal, and lung cancers. The research, published open-access in the journal Medicine, also identifies the types of benzodiazepines that carry the greatest cancer risk.

Long-term benzodiazepine use shown to effect cognitive function during current use and for years after drug discontinuation.

Oddly enough, it had occurred to me over this past year as I’ve been writing these essays for Mad in America that maybe I was “too healthy” to speak to the withdrawal experience with authenticity, to have street cred. It’s now a moot point. I write this not to scare people, but to present a reality. This reality has been difficult to accept, but the fact remains that my nervous system is more sensitive than before and might always be so, at least to some degree.

Medically-induced harm—affecting tens of millions of people worldwide—has taken the field decades to take seriously.

My doctor insisted that my symptoms could not be associated with withdrawal – they had to be symptoms of an underlying condition. I have since learned from legitimate sources that protracted withdrawal syndrome from benzodiazepines can intensify long before it abates, with some symptoms lasting for years.

Many have asked: “Why doesn’t my doctor/provider know what is happening to me?” Benzodiazepine tolerance and withdrawal are not new. So, why isn’t it simple to diagnose and treat? As both a health care provider and a withdrawal sufferer, I’d like to offer an inside and outside perspective on this question.

I remember the feeling, one of not exactly isolation but otherness. A sense that not only did I not fit in many places where I used to, but also that I lacked the energy to even try — to, like an actor, wear the skin of the old me for an hour or even a few minutes so that others would not feel uncomfortable in my quivering and clearly perturbed presence.

New guidelines recommend deprescribing benzodiazepine receptor agonists for adults.

Pictures are worth a thousand words. So I’ve chosen pictures to distill the mountain of mental health research I’ve examined over the last eight years. Three infographics summarize research on psychiatric drugs, and one asserts why I think Integrative Mental Health is the best path available for mental health recovery.

It is hard to believe that a year has gone past since I posted Playing the Odds: Antidepressant Withdrawal and the Problem of Informed Consent. The feedback I received underscored the more controversial aspects of SSRI toxicity.  Common themes concerned the abrupt onset of new symptoms 3 to 12 months after stopping the drug, reinstatement of the drug failing to help withdrawal related symptoms, the possibility that withdrawal-related symptoms can persist indefinitely and concerns about using benzodiazepines to help with tardive akathisia.

It’s stunning what a quarter milligram of a benzodiazepine can do to the body. I’ve been detoxing off a high dose of benzodiazepines since September of 2011. The first few months were a failure. But this past May, I found my expert and thought I had the formula. Things were going well for detoxing off a substance many deem more addictive that heroin. That is, I realized, until they weren’t.

While any effort to generate awareness and potentially curb the benzodiazepine epidemic is commendable, we have to ask ourselves, is Xanax just the scapegoat in this situation? Will legislative action and media attention for only one benzodiazepine out of so many make any difference?

One size fits all does not work. It is not possible to use the same tapering schedule for all patients who wish to stop with a certain drug. Therefore we had to come up with a flexible solution that was both practical and allowed doctors and patients to make the choice they deemed appropriate.

Beginning with the glamorization of Miltown in the 1950’s, the “I don’t care” pill was a way to ease the growing awareness that the world is indeed unsafe, and that something is deeply bankrupt in the promises of burgeoning science, technology, and industrialization. Still, we sought to heal these wounds through application of more of the same mentality – one of dominance, management, and suppression of all obstacles into submission. As our bodies, minds, and spirits become more and more separated from nature, each other, and ourselves, the worry, discomfort, and unease mount. Now that the going has gotten very tough, we are reaching for medications more than ever. Surely, however, turning off the smoke alarm is not the best way to deal with a fire.

Language is important. And when language dictates specific treatment protocols, it should be used with extreme scrutiny. Using the wrong words can put vulnerable people at risk—not only to their sense of self-worth, their sense of self-knowledge, and they way they are treated, but also to their health.

My sincere message to those whose vitality and lives have been sapped and zapped by this iatrogenic dis-order: most of us DO recover! And even if it is not without some benzo remnants lodged in our cellular memory, what we learn about our own resilience will guide us to places in our lives we didn't expect to reach. HOPE was my key through the arduous path of withdrawal and recovery.

"My studies in this area lead me to a very uncomfortable conclusion: Our citizens would be far better off if we removed all the psychotropic drugs from the market, as doctors are unable to handle them. It is inescapable that their availability creates more harm than good." - Peter Gøtzsche, MD; Co-founder of the Cochrane Collaboration

Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

Three out of four users of the sedative, zolpidem (brand name Ambien), do not follow FDA recommendations to reduce risk.

Benzodiazepine medications that are commonly used for calming or sedating people can sometimes apparently cause violent or aggressive responses in some people, according to...

The May issue of Addiction includes a review of pharmacological and phenomenological issues around benzodiazepine (BZD) and SSRI discontinuation.  Definitions, perceptions and management of the...

Confronting existential anxiety through “Basal Exposure Therapy” shows promising results in people withdrawing from psychotropic drugs.

It was the first time in my Klonopin journey it occurred to me the problem might not be inherent in me. The problem might actually be the Klonopin. Convinced my very life was at stake, I made the firm decision to get off the stuff once and for all.