European Parliament Votes For Clinical Trial Transparency

1
The European Parliament voted on Wednesday to ensure open reporting of European clinical trials, even when negative. The new laws, expected to take effect...

“Biologism in Psychiatry: A Young Man’s Experience of Being Diagnosed with ‘Pediatric Bipolar Disorder'”

8
The Journal of Clinical Medicine explores pediatric bipolar disorder through the eyes  a young American, whose story "reveals several issues that afflict contemporary psychiatry, particularly in...

Murphy Bill: Violates Civil Rights, Increases Government Intrusion and Control, and Ignores Scientific Research

18
HR 3717, authored by Congressman Tim Murphy, has been introduced in response to mounting concerns about the treatment of persons with mental health challenges. It is universally recognized that improvements are needed in the mental health system. Unfortunately, HR 3717 will have serious unintended consequences.

Hearing on H.R. 3717 (“Murphy Bill”) to Take Place Tomorrow

7
The House Subcommittee on Health will hold a hearing tomorrow (Thursday, April 3, 2014) on the “Helping Families in Mental Health Crisis Act," also...

Alan Dershowitz Will Work With Justina Pelletier’s Family on “Broader Constitutional Issues”

3
Harvard Law professor (emeritus) Alan Dershowitz will represent Justina Pelletier in her family's fight to regain custody from the state of Massachusetts and Boston...

Pharmaceutical Companies Lavishly Compensate Leaders of Academic Medical Centers

3
Leaders of medical schools and hospitals receive much more compensation from pharmaceutical companies than the doctors who have previously been scrutinized for drug company...

The Fat Lady Has Sung

58
In his latest paper, Martin Harrow focuses psychiatry's attention on a very specific question: Do antipsychotic drugs provide a long-term benefit as a treatment for psychotic symptoms? His findings are consistent with a larger body of evidence that all point to the same conclusion, which is that antipsychotics fail that efficacy test. And thus, I think it is fair to say that on this issue, the Fat Lady Has Sung, Psychiatry needs to rethink its use of these drugs.

Are Neuroleptics “Anti-Psychotic”? Harrow’s 20-Year Outcomes

40
Martin Harrow along with his colleagues T.H. Jobe and R. N. Faull has published another paper on the long term outcome of people who experienced a psychotic episode. Funded by a grant from the Foundation for Excellence in Mental Health Care, this paper adds to our knowledge of an extremely important and valuable study.

Antidepressants and Preterm Birth: More Concerning Findings

3
An important new research paper was published this week on the topic of antidepressant use during pregnancy and preterm birth.  The issue is a crucial one as preterm birth (i.e. birth at less than 37 weeks gestational age) is one of the most challenging problems facing the obstetrical community today.  Rates of preterm birth have been increasing over the past two decades.  Babies born early have increased risks of morbidity and mortality.  At the same time, rates of antidepressant use during pregnancy have increased dramatically.

“The Ugly Ducklings of Science”

0
Neuroskeptic explains "the ability of researchers to eventually squeeze support for a theory out of initially negative data," a problem that, though sometimes outright...

Overtreatment, Bereavement, and Antidepressants

A recent paper argues that prescribing antidepressants shortly after the death of a loved one is problematic . . . and a few days later, a Harvard academic publicly suggests prescribing antidepressants FOR bereavement. Wait, what?

20-Year Data Show Antipsychotics Do Not Reduce Psychosis

13
Martin Harrow's study tracing the effects of antipsychotics on 139 schizophrenia (SZ) and mood-disordered patients over 20 years, just published in Psychological Medicine, finds...

Increased Risk of Preterm Birth in Women Taking Antidepressants

1
A detailed meta-analysis of the published research on women taking antidepressants during pregnancy finds that the rate of preterm birth is nearly doubled in the third...

Anxiety Medication Associated With Significant Increase in Mortality Long-Term

0
A study of data from over 11 million patient records in the General Practice Research Database, "the largest anonymized, longitudinal primary care database in...

Drug Regulator Destroys Licensing Data After 15 Years

2
The Sunday Times of London reports on Peter Gotzsche's efforts to obtain pharmaceutical licensing data before the Medicines and Healthcare Products Regulatory Agency (MHRA)...

Childhood Trauma Predicts Risk of Violence in Psychosis

6
A study published in the Journal of Psychiatric Research finds the strongest association between a history of childhood trauma and the risk of violence...

Zoloft Affects Sperm Qualities: May Affect Fertility

2
A study in Urology found that men receiving Zoloft for treatment of premature ejaculation had a significant reduction in sperm concentration and significant increase...

Half of Americans Believe in a Medical Conspiracy

8
Research published this week in JAMA Internal Medicine finds that about half of American adults believe in at least one medical conspiracy theory. "Science in...

Forest Labs’ Antidepressant Marketing Woes Continue

1
Forest Labs has been hit with a new lawsuit in Massachusetts, over misleading marketing of its antidepressant drugs Celexa and Lexapro to adolescents, even...

1BoringOldMan on Misusing the Tools of Clinical Neuroscience

0
1BoringOldMan picks up where he left off two years ago - critiquing Robert Gibbons' misuse of statistical analysis to claim that antidepressants were both...

Glaxo to Bring Doctors In-House as Educational Speakers

0
GlaxoSmithKline, which previously announced it would suspend the practice of paying outside doctors to promote drugs, has announced that it will instead hire doctors...

ADHD Medication Slows Growth, Increases Obesity

0
Treating attention deficit/hyperactivity disorder (ADHD) with stimulants affects growth and is likely to cause a higher BMI in later adolescence, according to research from...

Psych Med Prescribing After Perinatal/Neonatal Death

0
Research from MIA blogger Jeffrey Lacasse finds that "at present, there exists no rigorous evidence to support the prescription of Ads (antidepressants) in bereavement....

Genetics of Bipolar Disorder

7
Research from the Semel Institute for Neuroscience and Human Behavior at USC finds that "The standard concept of genetic testing includes at least three...

The Role of Emotion and Internal Experience in Obsessive Compulsive Disorder

0
Research from Newcastle University in the U.K. finds that "Increasing attention has focused on the role of emotion and internal experience in obsessive compulsive...