Thursday, February 20, 2020

Different Antipsychotics Have Different Effects on Brain Volume

First generation antipsychotics seem to cause general brain volume loss, while second generation antipsychotics seem to both increase and decrease the thickness of different parts of the brain.

FDA-approved Ads Misinform Patients About Antipsychotics and Motor Dysfunction

Food and Drug Administration-approved information and public advertisements are misleading the public about the actual neurodegenerative risks from second-generation antipsychotics.

What Do Antidepressants in Drinking Water Do to Birds?

Ever higher levels of pharmaceutical drugs are turning up in drinking water supplies, and an op-ed in the UK Mirror discusses a study that...

Thoughtful Insight, Not Lack of It, Drives Some Patients to Quit Psychiatric Medications

Rather than a "lack of insight," it is actually a thoughtful weighing of complex risks and benefits that ultimately drives some people diagnosed with bipolar disorder to eschew psychiatric medications, according to a qualitative study in the Journal of Affective Disorders. And these people often develop sophisticated strategies in their efforts to manage without medications.

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

Psychiatric Medication Use Associated with Triple the Risk of Stroke

Common psychiatric medications double the risk of heart attack and triple the risk of stroke, according to research presented at the Canadian Cardiovascular Congress...

Autism, Antidepressants, and Pregnancy: The Basics

This month, the seventh study and eighth study came out on the topic of antidepressant exposure during pregnancy and autism.  And these studies showed, as essentially all of the others have, that antidepressant use during pregnancy (principally with selective serotonin reuptake inhibitors or SSRIs) is associated with autism in the exposed children. With so many children being diagnosed with autism and so many women taking antidepressants during pregnancy, everyone wants to know: are these things (the antidepressants) associated with autism or not?  Quite frankly no one has the time to read through all eight scientific papers (and dozens more animal and basic science studies) to understand this important area, so I will do my best to briefly summarize it here.

ADHD Medication Slows Growth, Increases Obesity

Treating attention deficit/hyperactivity disorder (ADHD) with stimulants affects growth and is likely to cause a higher BMI in later adolescence, according to research from...

Antidepressants Seem to Increase Heart Disease in the Elderly

Depressed elderly people are more likely to suffer heart disease not because of their depression, but apparently due to antidepressant drugs.

More Discussion of Antidepressant Withdrawal Effects

-Forensic psychiatrist Andrew Shepherd reviews a recent study on withdrawal effects from coming off antidepressant drugs.

Pfizer Sued Over Zoloft’s Failure to Beat Placebo

A lawsuit filed Wednesday in San Jose, California seeks federal approval for two class-action lawsuits representing all U.S. users of the antidepressant Zoloft, accusing...

Replacing Pain with Pain: Hazards of Antidepressant Use for Chronic Pain Relief

The paradox of relieving chronic pain with an antidepressant (and a new set of symptoms).

Gradual Tapering is Most Successful for Withdrawal from Antipsychotics

Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

New Antidepressant Shows Little Benefit, Significant Risks

Patient Drug News advises avoiding use of the antidepressant Vortioxetine (also called Brintellix or Trintellix), because the most recent evidence from the FDA shows...

Semen Abnormalities Associated with SSRI Antidepressants

The French non-profit organization Prescrire has produced a special report about the impacts of SSRI antidepressants on male fertility.

Differentiation of SSRI and Benzo Dependence/Withdrawal “Not Rational”

Researchers from the Cochrane Center and University of Copenhagen in Denmark, publishing in the May issue of Addiction, "explore the rationale for claiming that...

Lilly Faces First Week of “Bellwether” Cymbalta Withdrawal Lawsuit

Calling it “Poison,” plaintiff Claudia Herrera testified she would not have taken Eli Lilly's drug Cymbalta had she known the risks. Lilly hid the risks of...

Study Shows Success With Reduced Antipsychotic Use

People who reduced antipsychotic use by tapering were doing just as well after five years as those who continued using the drugs.

Over One Thousand Boys Grew Breasts “Probably” Caused By Common Psychiatric Medication

According to an ex-chief of the FDA, Johnson & Johnson knew long before it started warning people that Risperdal could cause boys to grow breasts.

Certain Antidepressants, Sleep Aids Associated with Higher Dementia Risk

Greater cumulative doses of drugs that are anticholinergic or block the neurotransmitter acetylcholine are associated with significant increases in dementia and Alzheimer's.

Antidepressant Use Climbs as Patients Find it Difficult to Discontinue

Findings point to the role of withdrawal symptoms and prescriber practices in long-term antidepressant use.

J&J Loses Case Over Risperdal Antipsychotic Causing Male Breast Growth

A jury decided Johnson & Johnson must pay a Philadelphia man $2.5 million in damages "for failing to warn that its Risperdal antipsychotic could cause gynecomastia."

Lithium May Cause Sexual Dysfunction — More Research Needed

Lithium appears to reduce libido and sexual function, and more research into the problem is needed.

Report Calls For Policy Changes In Response To Dependence and Withdrawal From Prescribed Drugs

Statistics from the UK reveal that prescriptions for painkillers and antidepressants continue to rise despite concerns over dependence and debilitating withdrawal effects. The British Medical Association (BMA) Board of Science has released a report that acknowledges changes to medical practice, research and policy necessary for addressing the dependence and withdrawal effects of benzodiazepines, opioids, and antidepressants.

Follow Us

19,639FansLike
11,994FollowersFollow
3,820SubscribersSubscribe