Friday, June 5, 2020

MIA News Archives

Psychiatrists Argue For More Attention to Iatrogenic Harms

Psychiatrists argue that current practice fails to account for the interaction of biological, psychosocial and iatrogenic factors.

Neuropsychological Tests Reveal Consequences of Polypharmacy

Neuropsychological assessments reveal the cognitive, occupational, and social impact of polypharmacy in psychiatry.

No Good Evidence That Antidepressants Prevent Relapse

Trials of antidepressants for relapse prevention are confounded by withdrawal effects caused by the drugs.

Peer-Support Groups Were Right, Guidelines Were Wrong: Dr. Mark Horowitz on Tapering Off Antidepressants

In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.

Gradual Tapering is Most Successful for Withdrawal from Antipsychotics

Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.

Stopping SSRI Antidepressants Can Cause Long, Intense Withdrawal Problems

In the first systematic review of withdrawal problems that patients experience when trying to get off SSRI antidepressant medications, researchers found that withdrawing from SSRIs was comparable to trying to quit addictive benzodiazepines.

Researchers: Antidepressant Withdrawal, Not “Discontinuation Syndrome”

Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.

SNRIs Added to the List of Drugs with Potential Withdrawal Symptoms

New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

Very Slow Tapering Best For Antidepressant Withdrawal

A new article in Lancet Psychiatry finds that slower tapering of SSRIs is better for preventing antidepressant withdrawal effects.

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

Long-term Use of Lithium Can Cause Kidney Failure

A third of patients who have taken the common psychiatric medication lithium for over ten years have developed "chronic renal failure" from the drug.

Lithium May Cause Sexual Dysfunction — More Research Needed

Lithium appears to reduce libido and sexual function, and more research into the problem is needed.

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

Antidepressants Actually Reduce Serotonin Levels

Common scientific beliefs about serotonin levels in depression and how antidepressants act on the brain appear to be completely backwards.

Danish Study Finds Better 10-year Outcomes in Patients Off Antipsychotics

Study finds that 74% of patients with a psychotic disorder off antipsychotics at end of 10 years are in remission.

Different Antipsychotics Have Different Effects on Brain Volume

First generation antipsychotics seem to cause general brain volume loss, while second generation antipsychotics seem to both increase and decrease the thickness of different parts of the brain.

Major Risks from Drug Interactions in Common Psychiatric Polypharmacy

It is very common for psychiatric patients, especially those diagnosed with schizophrenia, to be prescribed two or more psychiatric medications at once, and this...

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

Study Finds Improved Functioning for ‘Schizophrenia’ Without Antipsychotics

Long-term treatment with antipsychotic drugs is currently considered the standard treatment for patients diagnosed with ‘schizophrenia.’ A new study challenges this practice, however. The...

Prescribing Benzodiazepines As-Needed Leads to Abuse

A new study reported on in Medscape, examined risk factors for misuse of benzodiazepines (drugs such as Xanax, Ativan, and Klonopin). The researchers found that patients who had been prescribed the medication on an as-needed basis were more likely to end up abusing it than those who had been prescribed a standing dose.

More Psychological Supports Needed to Manage Antidepressant Discontinuation

Study reviews psychological interventions for antidepressant discontinuation.

Common Benzodiazepine Sedatives May Induce Aggression

Benzodiazepine medications that are commonly used for calming or sedating people can sometimes apparently cause violent or aggressive responses in some people, according to...

Antipsychotic-induced Sexual Dysfunction Underreported

Researchers found some antipsychotics to be worse than others for causing sexual dysfunction.

“Treatment Resistant” Schizophrenia Strongly Linked to Dopamine Supersensitivity

Over 70% of schizophrenia patients who are "treatment resistant" have apparently developed dopamine supersensitivity psychosis from long-term use of antipsychotic medications.

New Research on Patient-Centered Deprescribing for Antipsychotics

Researchers review the risks and benefits of deprescribing from antipsychotic drugs and advocate for a patient-centered approach to tapering.

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