Friday, January 17, 2020

Biological Explanations for Antidepressant Withdrawal

Two South African researchers review scientific understanding of the brain changes that lead to antidepressant discontinuation syndrome (ADS) in Human Psycho-pharmacology: Clinical and Experimental....

British Medical Association Takes On Prescription Drug Dependence

Last year the British Medical Association (BMA) released a report on dependence and withdrawal from prescription drugs including benzodiazepines, z-drugs, opioids, and antidepressants. Now,...

Long-term Use of Lithium Can Cause Kidney Failure

A third of patients who have taken the common psychiatric medication lithium for over ten years have developed "chronic renal failure" from the drug.

Peer-Support Groups Were Right, Guidelines Were Wrong: Dr. Mark Horowitz on Tapering Off Antidepressants

In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.

Fear and Belief in “Chemical Imbalance” Prevent People from Coming Off Antidepressants

Researchers interviewed people who were given medical advice to discontinue antidepressants.

Major Risks from Drug Interactions in Common Psychiatric Polypharmacy

It is very common for psychiatric patients, especially those diagnosed with schizophrenia, to be prescribed two or more psychiatric medications at once, and this...

New Study Examines User Experience of Discontinuing Psychiatric Medications

Researchers find that support and self-care were helpful for users during discontinuation, but that mental health professionals were not very helpful.

Antidepressants Linked to Doubling of Failure of Dental Implants

People who take SSRI antidepressants are twice as likely to have their dental implants fail, according to McGill University researchers. In a press release,...

New Clinical Guidelines on Deprescribing Benzodiazepines

New guidelines recommend deprescribing benzodiazepine receptor agonists for adults.

Antidepressant Caused Six-fold Artery Plaque Build-up in Monkeys

Zoloft caused up to six-fold increases in build-up of atherosclerosis plaque in the coronary arteries of monkeys.

PTSD and Antidepressants Linked to Diabetes

A JAMA Psychiatry study found links between PTSD, type 2 diabetes, and antidepressants.

J&J Loses Case Over Risperdal Antipsychotic Causing Male Breast Growth

A jury decided Johnson & Johnson must pay a Philadelphia man $2.5 million in damages "for failing to warn that its Risperdal antipsychotic could cause gynecomastia."

Study Shows Success With Reduced Antipsychotic Use

People who reduced antipsychotic use by tapering were doing just as well after five years as those who continued using the drugs.

Antipsychotic Medications Are Causing Obsessive Compulsive Disorders

Common second-generation antipsychotic medications are causing symptoms of obsessive-compulsive disorder to emerge in many people who previously only had schizophrenia symptoms, according to a...

Antipsychotic-induced Sexual Dysfunction Underreported

Researchers found some antipsychotics to be worse than others for causing sexual dysfunction.

Benzos Fail to Prevent, May Increase PTSD

In a review of the evidence regarding benzodiazepines, researchers from the University of Michigan find that benzodiazepines used in the treatment of PTSD are...

Psychological Interventions Can Help When Tapering Off Antidepressants

Meta-analysis of antidepressant tapering finds CBT and MBCT can aid in tapering, but limited studies met inclusion criteria.

Gradual Tapering is Most Successful for Withdrawal from Antipsychotics

Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.

When Switching Antipsychotics, No Difference Between Immediate and Gradual Discontinuation

Review study compares outcomes of gradual vs. immediate antipsychotic discontinuation when switching from one drug to another.

Waking Blackouts On Sleep Drugs Can Lead to Dangerous Mishaps

In her blog on USC Annenberg's Reporting on Health, journalist Martha Rosenberg reviews some of the quantitative evidence and qualitatively bizarre anecdotal evidence of...

Certain Antidepressants, Sleep Aids Associated with Higher Dementia Risk

Greater cumulative doses of drugs that are anticholinergic or block the neurotransmitter acetylcholine are associated with significant increases in dementia and Alzheimer's.

Evidence Lacking for Antidepressant Safety in Nursing Mothers

A scientific review says we need to know much more about the risks of nursing mothers taking SSRIs.

Psychotropics During Pregnancy Raise Risk of Babies with Low Birth Weight, Hospitalizations

The use by mothers of any of four major classes of psychiatric medications during pregnancy significantly raises the risk that their babies will be born with low birth weights and will need to be hospitalized.

Antidepressants Actually Reduce Serotonin Levels

Common scientific beliefs about serotonin levels in depression and how antidepressants act on the brain appear to be completely backwards.

New Form of Mice Experiment Reveals Antidepressant’s Dangers Earlier

Scientists from the University of Utah say they have discovered a new way of doing mice experiments that more sensitively and quickly reveals negative...

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