Wednesday, April 8, 2020

Antipsychotic Drug Associated with Potentially Fatal Skin Rash

The US Food and Drug Administration is warning the public that the antipsychotic medication ziprasidone "is associated with a rare but serious skin reaction...

Psychiatrists Argue For More Attention to Iatrogenic Harms

Psychiatrists argue that current practice fails to account for the interaction of biological, psychosocial and iatrogenic factors.

When Switching Antipsychotics, No Difference Between Immediate and Gradual Discontinuation

Review study compares outcomes of gradual vs. immediate antipsychotic discontinuation when switching from one drug to another.

What Do Antidepressants in Drinking Water Do to Birds?

Ever higher levels of pharmaceutical drugs are turning up in drinking water supplies, and an op-ed in the UK Mirror discusses a study that...

Major Risks from Drug Interactions in Common Psychiatric Polypharmacy

It is very common for psychiatric patients, especially those diagnosed with schizophrenia, to be prescribed two or more psychiatric medications at once, and this...

New Antidepressant Shows Little Benefit, Significant Risks

Patient Drug News advises avoiding use of the antidepressant Vortioxetine (also called Brintellix or Trintellix), because the most recent evidence from the FDA shows...

Researcher: 60,000 Americans Now Taking Antipsychotics Will Die Prematurely

-A fired government health economist says that his research was showing that 60,000 Americans now taking antipsychotic medications will die prematurely.

Prenatal Exposure to SSRIs Significantly Increases Autism & Developmental Delays

Research on 966 mother-child pairs from the Childhood Autism Risks from Genetics and the Environment (CHARGE) Study finds that prenatal SSRI exposure was nearly 3...

Neuroleptic Drugs and Violence

Neuroleptic Drugs and Violence by Catherine Clarke SRN, SCM, MSSCH, MBChA. and Jan Evans MCSP. Grad Dip Phys.

Psychiatric Medication Use Associated with Triple the Risk of Stroke

Common psychiatric medications double the risk of heart attack and triple the risk of stroke, according to research presented at the Canadian Cardiovascular Congress...

Certain Antidepressants, Sleep Aids Associated with Higher Dementia Risk

Greater cumulative doses of drugs that are anticholinergic or block the neurotransmitter acetylcholine are associated with significant increases in dementia and Alzheimer's.

Antidepressants Seem to Increase Heart Disease in the Elderly

Depressed elderly people are more likely to suffer heart disease not because of their depression, but apparently due to antidepressant drugs.

Prenatal Antidepressant Exposure Raises Risk to Newborn of Pulmonary Hypertension

Researchers from Canada find the risk of persistent pulmonary hypertension of the newborn is increased for infants exposed to SSRIs in late pregnancy. Results...

Study Finds Improved Functioning for ‘Schizophrenia’ Without Antipsychotics

Long-term treatment with antipsychotic drugs is currently considered the standard treatment for patients diagnosed with ‘schizophrenia.’ A new study challenges this practice, however. The...

Opioid Use in Pregnancy Dangerous and Understudied

Nora Volkow, the director of the National Institute on Drug Abuse (NIDA), authored an editorial for BMJ this month warning that the opioid abuse epidemic could have dangerous consequences for pregnant women. While the effects of opioid exposure on the developing brain are yet unknown, research suggests that infants may suffer from withdrawal syndrome, nervous system defects, and impaired attachment with the mother.

Health Canada Adds Suicide Warning to ADHD Medications

Stronger warnings on the risk of suicidal thoughts and behaviors are being incorporated into the prescribing information for ADHD drugs in Canada.

Replacing Pain with Pain: Hazards of Antidepressant Use for Chronic Pain Relief

The paradox of relieving chronic pain with an antidepressant (and a new set of symptoms).

More Discussion of Antidepressant Withdrawal Effects

-Forensic psychiatrist Andrew Shepherd reviews a recent study on withdrawal effects from coming off antidepressant drugs.

African American and Hispanic Youth Discontinue ADHD Treatment at Higher Rates than White Youth

Study examines racial and ethnic disparities in the quality of care for Medicaid-enrolled children starting ADHD medication.

2X Risk of Postpartum Hemorrhage Antidepressants

A study of 106,000 pregnant women with a diagnosis of mood or anxiety disorder, by researchers from Harvard, Duke, Michigan State and the university...

Increased Risk of Preterm Birth in Women Taking Antidepressants

A detailed meta-analysis of the published research on women taking antidepressants during pregnancy finds that the rate of preterm birth is nearly doubled in the third...

Pfizer Sued Over Zoloft’s Failure to Beat Placebo

A lawsuit filed Wednesday in San Jose, California seeks federal approval for two class-action lawsuits representing all U.S. users of the antidepressant Zoloft, accusing...

Over One Thousand Boys Grew Breasts “Probably” Caused By Common Psychiatric Medication

According to an ex-chief of the FDA, Johnson & Johnson knew long before it started warning people that Risperdal could cause boys to grow breasts.

Evidence Lacking for Antidepressant Safety in Nursing Mothers

A scientific review says we need to know much more about the risks of nursing mothers taking SSRIs.

Biological Explanations for Antidepressant Withdrawal

Two South African researchers review scientific understanding of the brain changes that lead to antidepressant discontinuation syndrome (ADS) in Human Psycho-pharmacology: Clinical and Experimental....

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