Friday, December 4, 2020

Prenatal Antidepressant Exposure Raises Risk to Newborn of Pulmonary Hypertension

Researchers from Canada find the risk of persistent pulmonary hypertension of the newborn is increased for infants exposed to SSRIs in late pregnancy. Results...

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

Autism, Antidepressants, and Pregnancy: The Basics

This month, the seventh study and eighth study came out on the topic of antidepressant exposure during pregnancy and autism.  And these studies showed, as essentially all of the others have, that antidepressant use during pregnancy (principally with selective serotonin reuptake inhibitors or SSRIs) is associated with autism in the exposed children. With so many children being diagnosed with autism and so many women taking antidepressants during pregnancy, everyone wants to know: are these things (the antidepressants) associated with autism or not?  Quite frankly no one has the time to read through all eight scientific papers (and dozens more animal and basic science studies) to understand this important area, so I will do my best to briefly summarize it here.

Major Risks from Drug Interactions in Common Psychiatric Polypharmacy

It is very common for psychiatric patients, especially those diagnosed with schizophrenia, to be prescribed two or more psychiatric medications at once, and this...

Antidepressant Use Climbs as Patients Find it Difficult to Discontinue

Findings point to the role of withdrawal symptoms and prescriber practices in long-term antidepressant use.

Very Slow Tapering Best For Antidepressant Withdrawal

A new article in Lancet Psychiatry finds that slower tapering of SSRIs is better for preventing antidepressant withdrawal effects.

Alarming Report on Antidepressant Side Effects

Drawing on analysis of data from websites such as Paxilprogress.org, ehealthforum.com, depression forums.org, about.com, medhelp.org, drugLib.com, topic.com and survivingantidepressants.org, researchers from the University of...

Danish Study Finds Better 10-year Outcomes in Patients Off Antipsychotics

Study finds that 74% of patients with a psychotic disorder off antipsychotics at end of 10 years are in remission.

Common Benzodiazepine Sedatives May Induce Aggression

Benzodiazepine medications that are commonly used for calming or sedating people can sometimes apparently cause violent or aggressive responses in some people, according to...

FDA-approved Ads Misinform Patients About Antipsychotics and Motor Dysfunction

Food and Drug Administration-approved information and public advertisements are misleading the public about the actual neurodegenerative risks from second-generation antipsychotics.

Pfizer Sued Over Zoloft’s Failure to Beat Placebo

A lawsuit filed Wednesday in San Jose, California seeks federal approval for two class-action lawsuits representing all U.S. users of the antidepressant Zoloft, accusing...

Psychiatrists Argue For More Attention to Iatrogenic Harms

Psychiatrists argue that current practice fails to account for the interaction of biological, psychosocial and iatrogenic factors.

FDA System for Recording Adverse Drug Effects Perilously Deficient

The system that the US FDA is using to gather and report on information about dangerous side effects from medications is extremely unreliable and...

Some Antidepressants Worse than Others for Causing Sexual Dysfunction

In a review of the scientific evidence about sexual dysfunction caused by antidepressants, Australian researchers determined that some of the medications are worse than...

New Study Examines User Experience of Discontinuing Psychiatric Medications

Researchers find that support and self-care were helpful for users during discontinuation, but that mental health professionals were not very helpful.

Antipsychotics During Pregnancy Linked to Infant Problems

“Live, healthy babies are the most common outcome following the use of antipsychotic medication in pregnancy,” conclude Australian researchers in a study that was...

Tapering Strips Help People Stop Using Antidepressants, Study Finds

A new study by Peter Groot and Jim van Os investigated whether tapering strips can help people stop using antidepressants.

Withdrawal studies up to 9/23/2005

M.W. Agelink, A Zitselsberger, E. Kleiser, Withdrawal symptoms after discontinuation of Venlafaxine (letter), Am. J. Psychiatry, 154, 10, October 1997, 1473-1474. G.W. Amsden, F. Georgian,...

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

Thoughtful Insight, Not Lack of It, Drives Some Patients to Quit Psychiatric Medications

Rather than a "lack of insight," it is actually a thoughtful weighing of complex risks and benefits that ultimately drives some people diagnosed with bipolar disorder to eschew psychiatric medications, according to a qualitative study in the Journal of Affective Disorders. And these people often develop sophisticated strategies in their efforts to manage without medications.

Social Support Improves Antipsychotic Discontinuation, Study Finds

A new study explores how people manage to discontinue antipsychotic medication and examines how social supports may improve outcomes.

Some Common Psychiatric Medications Associated With Pneumonia

Pneumonia cases in the elderly are strongly associated with use of anticholinergic medications, including benzodiazepines and tricyclic antidepressants.

Researchers: Antidepressant Withdrawal, Not “Discontinuation Syndrome”

Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.

Antidepressants Linked to Doubling of Failure of Dental Implants

People who take SSRI antidepressants are twice as likely to have their dental implants fail, according to McGill University researchers. In a press release,...

Study Finds Improved Functioning for ‘Schizophrenia’ Without Antipsychotics

Long-term treatment with antipsychotic drugs is currently considered the standard treatment for patients diagnosed with ‘schizophrenia.’ A new study challenges this practice, however. The...

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