Tuesday, December 10, 2019

ADHD Medication Slows Growth, Increases Obesity

Treating attention deficit/hyperactivity disorder (ADHD) with stimulants affects growth and is likely to cause a higher BMI in later adolescence, according to research from...

Different Antipsychotics Have Different Effects on Brain Volume

First generation antipsychotics seem to cause general brain volume loss, while second generation antipsychotics seem to both increase and decrease the thickness of different parts of the brain.

Waking Blackouts On Sleep Drugs Can Lead to Dangerous Mishaps

In her blog on USC Annenberg's Reporting on Health, journalist Martha Rosenberg reviews some of the quantitative evidence and qualitatively bizarre anecdotal evidence of...

Some Common Psychiatric Medications Associated With Pneumonia

Pneumonia cases in the elderly are strongly associated with use of anticholinergic medications, including benzodiazepines and tricyclic antidepressants.

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

“Treatment Resistant” Schizophrenia Strongly Linked to Dopamine Supersensitivity

Over 70% of schizophrenia patients who are "treatment resistant" have apparently developed dopamine supersensitivity psychosis from long-term use of antipsychotic medications.

Gradual Tapering is Most Successful for Withdrawal from Antipsychotics

Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.

Obesity in Men Diagnosed With ADHD as Children

A 33-year controlled, prospective study conducted as a collaboration by researchers in New York, Mexico, and Verona, Italy found that men diagnosed with ADHD...

2X Risk of Postpartum Hemorrhage Antidepressants

A study of 106,000 pregnant women with a diagnosis of mood or anxiety disorder, by researchers from Harvard, Duke, Michigan State and the university...

Social Support Improves Antipsychotic Discontinuation, Study Finds

A new study explores how people manage to discontinue antipsychotic medication and examines how social supports may improve outcomes.

What Do Antidepressants in Drinking Water Do to Birds?

Ever higher levels of pharmaceutical drugs are turning up in drinking water supplies, and an op-ed in the UK Mirror discusses a study that...

Thoughtful Insight, Not Lack of It, Drives Some Patients to Quit Psychiatric Medications

Rather than a "lack of insight," it is actually a thoughtful weighing of complex risks and benefits that ultimately drives some people diagnosed with bipolar disorder to eschew psychiatric medications, according to a qualitative study in the Journal of Affective Disorders. And these people often develop sophisticated strategies in their efforts to manage without medications.

New Antidepressant Shows Little Benefit, Significant Risks

Patient Drug News advises avoiding use of the antidepressant Vortioxetine (also called Brintellix or Trintellix), because the most recent evidence from the FDA shows...

More Evidence Antidepressants Might Induce Sexual Dysfunction Even After Stopping Them

A retrospective study in the Journal of Clinical Psychiatry examined cases of people who suffered sexual dysfunction that endured even after stopping taking SSRI antidepressants.

More Discussion of Antidepressant Withdrawal Effects

-Forensic psychiatrist Andrew Shepherd reviews a recent study on withdrawal effects from coming off antidepressant drugs.

Eli Lilly Defeats “Bellwether” Cymbalta Withdrawal Lawsuit

The Federal jury hearing the first of 5000 claims against Eli Lilly for hiding the risks of withdrawal symptoms associated with Cymbalta found that Lilly did not...

Sexual Dysfunction from Antipsychotics Common — But Poorly Monitored by Physicians

Describing the prevalence and management of adverse effects from antipsychotics as "a neglected area" of study, a team of researchers from the UK has published a systematic review in the Journal of Psychopharmacology. They aimed to identify the prevalence of, and management strategies for nine categories of adverse effects, including sedation, weight gain, metabolic syndrome, sexual dysfunction and cardiovascular effects.

FDA System for Recording Adverse Drug Effects Perilously Deficient

The system that the US FDA is using to gather and report on information about dangerous side effects from medications is extremely unreliable and...

Fear and Belief in “Chemical Imbalance” Prevent People from Coming Off Antidepressants

Researchers interviewed people who were given medical advice to discontinue antidepressants.

Study Finds Improved Functioning for ‘Schizophrenia’ Without Antipsychotics

Long-term treatment with antipsychotic drugs is currently considered the standard treatment for patients diagnosed with ‘schizophrenia.’ A new study challenges this practice, however. The...

J&J Loses Case Over Risperdal Antipsychotic Causing Male Breast Growth

A jury decided Johnson & Johnson must pay a Philadelphia man $2.5 million in damages "for failing to warn that its Risperdal antipsychotic could cause gynecomastia."

Biological Explanations for Antidepressant Withdrawal

Two South African researchers review scientific understanding of the brain changes that lead to antidepressant discontinuation syndrome (ADS) in Human Psycho-pharmacology: Clinical and Experimental....

More Psychological Supports Needed to Manage Antidepressant Discontinuation

Study reviews psychological interventions for antidepressant discontinuation.

Over One Thousand Boys Grew Breasts “Probably” Caused By Common Psychiatric Medication

According to an ex-chief of the FDA, Johnson & Johnson knew long before it started warning people that Risperdal could cause boys to grow breasts.

FDA-approved Ads Misinform Patients About Antipsychotics and Motor Dysfunction

Food and Drug Administration-approved information and public advertisements are misleading the public about the actual neurodegenerative risks from second-generation antipsychotics.

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