Depression

A study out of the University of Buffalo explores the use of Narrative Exposure Therapy to treat youth PTSD and substance abuse. “Trauma is...

Writing for the Harvard Health Blog, Dr. Nandinia Mani reconsiders the use of antidepressants in teens in light of the reanalysis of Study 329. ...

The warning label for the antidepressant Cymbalta downplayed the risks of withdrawal effects, according to consumer lawsuits being filed in courts across the country. “An estimated 44% to 78% of people who stop taking Cymbalta (also known as duloxetine) will suffer from withdrawal reactions,” yet the warning label “suggests the risk is greater than or equal to 1%.”

“Children from poorer families are more likely to experience changes in brain connectivity that put them at higher risk of depression, compared with children from more affluent families,” according to new research covered by Medical News Today. "Poverty doesn't put a child on a predetermined trajectory, but it behooves us to remember that adverse experiences early in life are influencing the development and function of the brain. And if we hope to intervene, we need to do it early so that we can help shift children onto the best possible developmental trajectories."

A study published this week in the Annals of Family Medicine reveals that opioid painkillers, when used long-term, can lead to the onset of depression. The researchers found that the link was independent of the contribution of pain to depression.

There is robust evidence for the long-term effectiveness of psychotherapy, and it also provides good value-for-money, according to a large randomized control trial published open-access this month in The Lancet. The researchers recommend that clinicians refer all patients with treatment-resistant depression to therapy.

The Guardian covers research out of Australia that found that levels of the “stress hormone” cortisol in the hair of 70 nine-year-old children corresponded to the number of traumatic events experienced by the child. “Childhood is an imperative and sensitive period of development, and when things go wrong it can have lifelong consequences, not just on mental health, but also on general health.”

In the SundayReview section of the New York Times Vicki Abeles discusses Stuat Slavin’s research on depression and anxiety in US schools. “Many of the health effects are apparent now, but many more will echo through the lives of our children,” says Richard Scheffler, a health economist at the University of California, Berkeley.

There is a growing body of evidence suggesting that being exposed to bullying in childhood can contribute to mental health problems later in life. In a new study, published in JAMA Psychiatry, the researchers found that children who reported being bullied at age eight were significantly more likely to seek treatment for mental health problems by age twenty-nine.

“According to a new study, the consequences of this wage gap extend beyond the checking account: women who earn less than their male peers...

“Those who possess the data control the story.” In the wake of the reanalysis of the infamous Study 329, where scientific data claiming the antidepressant Paxil was safe and effective for teens was egregiously manipulated, researchers are pushing for open access to raw data. “The issue here, scientists argue, is that without independent confirmation, it becomes too easy to manipulate data.”

Martha Rosenberg calls the reanalysis of Paxil and Study 329 “a victory for safety activists, medical reporters, the public and freedom of the press.” But, she warns, “many pro-pill doctors continue to fight evidence of Paxil’s suicide risks and similar SSRIs.”

On his website, Dr. Nardo details the hidden risks and bad science behind the growing practice of using atypical antipsychotics to augment antidepressant treatment for severe depression. The story of Atypical Antipsychotic Augmentation of Treatment Resistant Depression is a “prime example” “to illustrate how commercial interests have invaded medical practice.” “Besides the obvious dangers of the Metabolic Syndrome and Tardive Dyskinesia, these drugs don’t really do what they’re advertised to do – make the antidepressants work a lot better.”

“The Food and Drug Administration’s approval of pharmaceutical treatment for low sexual desire in women has launched a heated debate over the dangers and benefits of medicalizing sex,” Maya Dusenbery writes in the Pacific Standard. Is “female Viagra” a feminist victory or a product of clever faux-feminist marketing by Big Pharma?

Listen: NPR’s On Point with Tom Ashbrook discusses the new book “Moody Bitches: The Truth About the Drugs You’re Taking, The Sleep You’re Missing, the Sex You’re Not Having and What’s Really Making You Crazy,” by the psychiatrist Julie Holland.

Children of parents who suffer from depression have a severely heightened risk of mental health problems, but new research points to several factors that seem to strengthen young peoples’ resilience and predict good mental health.

A new NIH-funded study suggests that children from low-income environments are more likely to have neurological impairments. The researchers claim that these neurodevelopmental issues are “distinct from the risk of cognitive and emotional delays known to accompany early-life poverty.”

Boston College Psychologist Peter Gray writes for Aeon about the impact of the gradual erosion of children’s’ play in the United States. “Over the...

In the context of the Silicon Valley suicides, one mother offers her story about her daughter. “It’s my premise that not only the culture of Silicon Valley, but also, almost more importantly, the nature of the remedies that are being proposed in the name of mental health counseling, are to blame in these deaths.”

In Scientific American, Kasley Killam presents insights from research on “post-traumatic growth,” highlighting the importance of finding meaning or underlying significance in our struggles and misery. “The psychiatrist and Holocaust survivor Viktor Frankl wrote extensively about this process after observing that his fellow inmates in concentration camps were more likely to survive the horrific conditions if they held on to a sense of meaning.”

The Daily Telegraph reports on a warning published in the Medical Journal of Australia that urges doctors not to “jump the gun in prescribing patients the drug ketamine to treat depression.”

An analysis of medical records in the UK reveals that the use of certain antidepressants for depression is linked to a heightened risk for mania and bipolar disorder. The research, published this week in BMJ Open, found the strongest effect for serotonin reuptake inhibitors (SSRIs) and the antidepressant venlafaxine.

Psychologist William Copeland writes for Mental Health Recovery that “bullying can occur at any age and the effects of which remain harmful long after the behavior has been endured.” “We, as a society, are just beginning to understand and come to terms with the havoc that bullying wreaks on the emotional lives of its victims.

A phase 1 study for a stem cell derived agent that promotes the growth of new nerve cells in the brain demonstrated efficacy in a very small sample of patients diagnosed with major depressive disorder (MDD). The phase 1B study was published online December 8 in Molecular Psychiatry.

A new study, published this week in BMJ, found no major differences in the effectiveness of cognitive behavioral therapy (CBT) and antidepressants. When the researchers compared previous studies, they found no major differences in relapse rates or level of treatment response between those taking antidepressants and those undergoing CBT.