Non-Distressed Psychosis-Like Experiences Not Linked to Serious Mental Illness
Research from the University of Maryland finds that "Although 'psychosis-like experiences' (PLEs) may reflect elevated risk for onset of serious mental illness," further examination...
Antipsychotic Trials Show Increasing Placebo Response and Declining Drug Response
A new review of antipsychotic trials conducted over the last 24 years finds that the placebo response rate is steadily increasing, and drug response is decreasing.
New IRIS Guidelines for Early Intervention in Psychosis
The 'Initiative to Reduce the Impact of Schizophrenia" (IRIS) has updated its 1998 guidelines for early intervention in psychosis to state that not all people...
Understanding the Neurobiology of Post-SSRI Sexual Dysfunction
Post-SSRI sexual dysfunction (PSSD) may be a common adverse effect of antidepressants. Researchers are now attempting to understand the neurobiology behind it.
PTSD and Antidepressants Linked to Diabetes
A JAMA Psychiatry study found links between PTSD, type 2 diabetes, and antidepressants.
Improved Neural Development in Children Moved from Institutional Care
Researchers from Harvard, Tulane, the University of Maryland and Boston Children's hospital compared MRI and EEG scans of 20 normally developing Romanian children with...
Family Economic Context Linked to Adolescents’ Antipsychotic Use
In a study of the Swedish Medical Birth Registry published in the British Medical Journal, researchers identified all 324,510 single children born between 1988...
GlaxoSmithKline (GSK) Will Stop Paying Doctors to Promote Drugs
In a first for a major drug company, GlaxoSmithKline, the British pharma that was fined $3 billion for illegal marketing of Paxil and Wellbutrin,...
Antipsychotics Increase Risk of Dementia; New Research Illuminates Why
In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.
Thoughtful Insight, Not Lack of It, Drives Some Patients to Quit Psychiatric Medications
Rather than a "lack of insight," it is actually a thoughtful weighing of complex risks and benefits that ultimately drives some people diagnosed with bipolar disorder to eschew psychiatric medications, according to a qualitative study in the Journal of Affective Disorders. And these people often develop sophisticated strategies in their efforts to manage without medications.
Massive Number of Antidepressant Meta-Analyses Biased By Industry
A massive number of meta-analyses of antidepressant clinical trials have financial conflicts of interest and are unduly influenced by pharmaceutical companies, according to a review to be published in an upcoming issue of the Journal of Clinical Epidemiology. Researchers also found that meta-analyses with industry ties almost never report any negative findings in their abstracts.
Training Health Workers in Therapy Leads to Improvements and Less Medication Use
A Nigerian study finds that more than three-quarters of patients improved, even when only 13% were prescribed medication.
Australia’s Billion-Dollar Question: Why Is Mental Health Not Improving With Better Access?
Amid growing mental health crisis, research raises questions about the mass rollout of brief psychotherapies in Australia.
Antidepressant Use Associated With More Violent Suicide Attempts
A new study found that taking an antidepressant medication was associated with a heightened risk of suicide using violent means.
New Study Finds Brain Changes in Newborns Exposed to Antidepressants
A fist of its kind neuroscience study, published this month in Cerebral Cortex, found changes in the brain electrical activity of infants exposed to SSRI antidepressants during pregnancy.
Canadian Who Killed Son While on Medication Joins Forces With U.S. Dad Who Killed...
David Crespi is serving a life sentence following his 2006 slaying of his five-year-old twin girls while being treated with antidepressant medications. David Carmichael,...
Rise in Suicides Baffles Military
The New York Times reports that the "baffling" rise in suicide rates in the U.S. military is not correlated to deployment, as is often...
Antidepressants Do Not Improve Quality of Life
A new study found that taking antidepressants did not improve quality of life.
Kenneth Kendler: “Implausible” That Psychiatric Diagnoses Even “Approximately True”
In JAMA Psychiatry, prominent psychiatrist Kenneth Kendler writes that psychiatric diagnoses are “working hypotheses, subject to change.”
Four Leading Antipsychotics Aren’t Safe or Effective in Older Adults
A 5-year study funded by the National Institute of Mental Health and conducted by U.C. San Diego School of Medicine, Stanford University and the...
Large German Anti-Stigma Campaign Shows Little Effect on Attitudes
“Overall, this study showed that the information and awareness campaign had almost no significant effects on the general public's attitudes toward people affected by either schizophrenia or depression,” the researchers, led by German medical sociologist Anna Makowski, wrote. “One could assume that deeply rooted convictions cannot be modified by rather time-limited and general activities targeted at the public.”
Childhood Trauma Predicts Lack of Response to Antidepressants
Research in Translational Psychiatry finds that childhood maltreatment and trauma predict a greater likelihood of developing chronic depression, and a reduced likelihood of responding to treatment...
D-Cycloserine Supplement Does Not Add Much to Exposure Therapy
A closer look at a new study reporting that the supplement D-cycloserine improved anxiety when used with exposure therapy.
Mindfulness Therapy May Be More Effective Without Antidepressants
While an estimated 74-percent of patients diagnosed with major depression receive a prescription for an antidepressant, new research reveals that mindfulness-based cognitive therapy (MBCT)...
Controversial Exposure Therapy for PTSD Challenged
Research published in the May 2015 issue of The American Journal of Psychiatry questions the use of exposure therapy, the "gold standard" treatment for patients...
