Mood Stabilizers

A third of patients who have taken the common psychiatric medication lithium for over ten years have developed "chronic renal failure" from the drug.

Bipolar drug therapy is a balancing act of benefits vs. harms. Odds of attributable benefit cluster in a 15-25% band, so 75%-85% don’t see substantial benefit. Stated differently, if five people take a bipolar drug, only one is likely to see substantial improvement due to it, but all five will have side effects.

Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.

With deep regret, Mad in America announces another loss in our contributor community. Julie C. Greene, writer and antipsychiatry advocate, lost her battle with kidney disease on November 29 at her home in Beaver Falls, Pennsylvania. Julie had been an MIA blogger since 2014, including several pieces on the dangers of lithium.

Singer Sinead O'Connor announced on her website that after several "second opinions" she has learned "I do not in fact suffer from Bi Polar...

I was first given Lithium Carbonate in the spring of 1984, and I was taken off Lithium by my attending physician in 1996, but left on other drugs. It took me until 2012 to realize psychiatry is a sham. So often people tell me, “I don’t care what my life is like ten years from now. I only want to feel good now.” I may have said the same thing twenty years ago. Now I have the hindsight to know that my viewpoint back then was juvenile at best. I try to warn other patients these days. It’s hard to joke around about something that kills people.

"My studies in this area lead me to a very uncomfortable conclusion: Our citizens would be far better off if we removed all the psychotropic drugs from the market, as doctors are unable to handle them. It is inescapable that their availability creates more harm than good." - Peter Gøtzsche, MD; Co-founder of the Cochrane Collaboration

by Chaya Grossberg July 25, 2012 He also told me the shrinks were changing around his drugs and adding more.  They added an antidepressant or two to the Lithium and increased doses and eventually he seemed to have very little life left in him.  Our phone calls became trying for he was so down, practically dead sounding a lot of the time, and I felt unable to do anything or say anything to make a difference.  To even try felt futile and I wondered if talking to me at all was becoming the burden of yet another person he couldn't connect with. In the early years, he liked to think of us as being in the same boat, both mentally ill, since I'd also had a meltdown and I also am extremely sensitive and go through extreme states.  But as the years went by, especially towards the end, I seemed to be in the ever growing “other” camp in his eyes, which meant I was yet another person who didn't get what it was like to be him. And at that point I can confirm I did not, and perhaps did not want to.

An analysis of medical records in the UK reveals that the use of certain antidepressants for depression is linked to a heightened risk for mania and bipolar disorder. The research, published this week in BMJ Open, found the strongest effect for serotonin reuptake inhibitors (SSRIs) and the antidepressant venlafaxine.

The hearing for Bill H4062: Informed Consent for Benzodiazepines and Non-benzodiazepine Hypnotics took place on Monday – in the middle of an April snowstorm! The discussion clarified some important points in the legislation and gave survivors an opportunity to tell their stories. I was so proud to be there and witness the courage, camaraderie, resilience, advocacy, and vulnerability of fellow survivors. This legislation is our chance to be heard. As one survivor said, through tears, to the committee, “Do not let my suffering be in vain. I beg you to pass this bill.”

Lithium appears to reduce libido and sexual function, and more research into the problem is needed.

My name is Leah Harris and I'm a survivor. I am a survivor of psychiatric abuse and trauma. My parents died largely as a result of terrible psychiatric practice. Psychiatric practice that took them when they were young adults and struggling with experiences they didn’t understand. Experiences that were labeled as schizophrenia. Bipolar disorder. My parents were turned from people into permanent patients. They suffered the indignities of forced treatment. Seclusion and restraint. Forced electroshock. Involuntary outpatient commitment. And a shocking amount of disabling heavy-duty psychiatric drugs. And they died young, from a combination of the toxic effects of overmedication, and broken spirits.

If I had remained med compliant I wouldn’t understand the simple joys of caring about my hygiene and my surroundings. I’ve wanted to write about this for a long time but I’ve not done it and I think it’s because I still have shame around how slovenly I became. I hid it from others fairly well most of the time, but I couldn’t hide it from myself. The fact is the drugs stripped me of some very basic elements of human care. When one doesn’t care about their immediate environment and their bodies, they really just don’t care about themselves. It’s a very painful place to be and yet when it’s caused by drugs it’s all muted and weird and not really who we are at all and so really all that is left is horrible shame.

The Journal of ECT, looking at the question of whether antidepressant medications at the start of ECT reduced post-ECT relapse in a sample of...

When I first interviewed Brandon Banks, in the spring of 2008, while researching Anatomy of an Epidemic, he had recently entered Elizabethtown Community College...

Rising prescriptions for psychiatric medications are partly a result of longer-term treatment and increasing population, according to an article by Joanna Moncrieff and Stephen...

When I was a young adult, I was misdiagnosed with bipolar disorder and placed on lithium. I am 61 years old now, living on the edge of end-stage kidney disease. If I could undo everything, by all means, I would not have taken this drug. It is not safe for anyone at any age.

I lived through forced ECT from 2005-2006 at the Institute of Living in Hartford, Connecticut. My experience with ECT was the impetus for me to become involved in the antipsychiatry and Mad Pride movements, although I am not entirely opposed to voluntary mental health treatment. The following is the comment I submitted to the FDA on its proposal to down-classify the ECT shock device.

The authors of an article in Journal of Psychosocial Nursing reviewed the literature on psychotropic PRN medications in order to respond to a request to...

On October 23, the New York Times ran a very nice feature story about a Los Angeles woman, Keris Myrick, who, even though she...

Psychologist and Professor Amber Gum has published the story of her personal journey of rethinking psychotropic medication in a special issue on "The Politics of Mental Health" in The Journal of Medicine and the Person. Influenced by Mad in America and the work of Robert Whitaker, Gum became aware of evidence that “suggests that psychotropic medications are less effective and more harmful than most believe” and now hopes to encourage other mental health professionals and researchers to engage in open-minded, critical self-assessment of standard practices.

Analysis of longitudinal data from 2000-2014 demonstrate mortality gap is widening between persons with a diagnosis of bipolar or schizophrenia compared to the general population

Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”

The idea of spending more time as a bureaucrat in the US Embassy in Iceland did not appeal to me. I longed for the freedom that academics have. While pursuing that dream I stumbled into the world of international media, “chemical imbalance”, book publishing and a greedy professor of psychiatry which was a prelude to my second annus horribilis.