Genetic Markers do not Predict Response to Antidepressants
Researchers from 11 nations in Europe and North America find, in the largest study to date of possible links between genetic markers and antidepressant...
SSRI Antidepressants Appear to Raise Risk of Serious Respiratory Disease in Newborns
A new study has reinforced earlier warnings that taking SSRI antidepressants late in pregnancy appears to put mothers at a slightly increased risk of having newborns with persistent pulmonary hypertension.
Exposure to Antidepressants in the Womb Linked to Autism
Researchers, publishing in Toxicology Research, review the evidence that antidepressant exposure in the womb is linked to autism spectrum disorders (ASD) in humans.
Study Finds Antidepressants in Pregnancy Increase Risk for Speech Disorders
A new study published this week in JAMA Psychiatry indicates that infants are more likely to develop speech or language disorders if they are exposed to antidepressants during pregnancy.
Hypertension in Pregnancy 50% More Likely With SSRIs
Researchers in Montreal found in a sample of 1,216 pregnant women that those who used antidepressants were at least 50% more likely to experience...
Researchers Push Back Against Recommendation to Combine Antidepressants for Suicide Prevention
Researchers challenge the recommendation of starting two antidepressants simultaneously to increase preventative effects against suicide.
Paxil Linked to Birth Defects, Cardiac Malformations
According to the CDC, January is National Birth Defects Prevention Month. New research continues to link various SSRI antidepressants with birth defects and neurological abnormalities in newborns. The latest study to examine this topic, a meta-analysis led by Dr. Anick Bérard, found a 23% increased risk for birth defects, and a 28% increased risk for heart problems, in the infants of women who took the SSRI Paxil (paroxetine) during their first trimester.
Psychotropics During Pregnancy Raise Risk of Babies with Low Birth Weight, Hospitalizations
The use by mothers of any of four major classes of psychiatric medications during pregnancy significantly raises the risk that their babies will be born with low birth weights and will need to be hospitalized.
Fava: Antidepressants in Severe Cases, Short Duration Only
Giovanni Fava has published an integrative analysis of the different sources of scientific research into antidepressants in Psychotherapy and Somatics. “The use of antidepressant...
Antidepressants Worsen Rapid Cycling in Bipolar Depression
-SSRI antidepressant medications contribute to a significant worsening of emotional "rapid cycling" in patients diagnosed with bipolar disorder.
Antidepressants & Sexual Function
Two studies of the effects of antidepressants on sexual function - one on the relative effects across classes of antidepressants on men, the other...
Semen Abnormalities Associated with SSRI Antidepressants
The French non-profit organization Prescrire has produced a special report about the impacts of SSRI antidepressants on male fertility.
SSRIs Significantly Increase Falls in Dementia, Even at Low Doses
Researchers in the Netherlands followed 248 nursing home residents with dementia for two years, finding that even 25% of the defined daily dose of...
Turmeric as Effective as Prozac, With no Side-Effects
A randomized, controlled study by the Department of Pharmacology of Government Medical College in Bhavnagar, Gujarat, India found that in a study of 60...
Increased Bone Fracture Risk from SSRI Antidepressants
"Evidence from longitudinal, cross-sectional, and prospective cohort studies suggests that the use of antidepressants at therapeutic doses is associated with decreased bone mineral density...
FDA: Antidepressant Trials Have Not Adequately Reported Sexual Dysfunction Side Effects
US Food and Drug Administration scientists want to better evaluate side effects of sexual dysfunction associated with antidepressant drugs.
Pooling Data May Hide Negative Outcomes for Antidepressants
A new study, published in Psychological Medicine, found evidence for a specific type of publication bias distorting the evidence about antidepressant efficacy.
Drug Treatment for Borderline Personality Disorder Not Supported By Evidence
New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”
Study Links SSRIs to Violent Crime in Youth
Individuals between the ages of 15 and 24 are more likely to commit a violent crime if they are taking an SSRI antidepressant than if they are not, according to new research out of Sweden. The study published in PLoS Medicine on Tuesday, suggests "warnings about the increased risk of violent behavior among young people taking SSRIs might be needed.”
Treating Anxiety by Tapering Off Antidepressants
Researchers from Samaritan Mental Health in Corvallis, Oregon successfully treated 12 patients for anxiety by discontinuing their antidepressant medications. Some received alternative medications for...
Legal Journal Says Antidepressants Can Cause Violence and Suicide
Antidepressants have been reported to cause a state called “akathisia,” where people feel extremely agitated and restless and may become preoccupied with thoughts of...
Bereaved Parents Prescribed Meds Quickly, Stay on Meds Long-Term
MiA blogger Jeffrey Lacasse's study of psychiatric prescribing in response to perinatal/neonatal death (co-authored with Joanne Cacciatore) finds that 37% of participants in an...
Youth Antidepressant Use Associated With Increased Suicide and Self-Harm
National data on rates of youth antidepressant prescription, suicide, and self-harm in Australia sparks public health debate about drug safety.
Antidepressant Exposure In Utero May Negatively Impact Motor Skills in 2-Year-Old Children
A new study in Frontiers of Pharmacology finds that antidepressant use during pregnancy is linked to reduced motor skills in children at 2 years...
Strategies for Tapering and Discontinuing Antidepressants
A new review of strategies to support both patients and practitioners through the process of discontinuing antidepressants.