Saturday, November 27, 2021

Children on Antipsychotics 50% More Likely to Develop Diabetes

Antipsychotic drugs increased the risk of children developing diabetes by 50%, and with an antidepressant added, their risk doubled.

Antipsychotic Risperidone Raises Risk of Male Breast Enlargement

Taking the antipsychotic medication risperidone significantly increases men's chances of developing gynecomastia, or breast enlargement, according to a study by University of British Columbia...

Antipsychotics for Depression: Added Risk for Little Benefit

A review of research on antipsychotic medications as an adjunctive treatment for depression published this week in PLoS Medicine finds that the widespread practice...

Neuroleptic Malignant Syndrome Linked to Polypharmacy, Benzos, and Race

Research from London and Taipei finds that neuroleptic malignant syndrome (NMS) is associated with the number of different antipsychotics used (polypharmacy), rather than the overall...

Antipsychotics Ineffective Against Cocaine, Stimulant Addictions

Although cocaine and psychostimulant dependence are thought to be related to increased dopamine release, research from Tokyo and Long Island finds that the effect...

Osteoporosis Associated with Antipsychotic Treatment

Chinese researchers find, in a literature review for the International Journal of Endocrinology find an increased rate of osteoporosis among people with a schizophrenia...

Antipsychotics Again Strongly Linked to Falls and Fractures

Three independent studies in two journals reported strong links between antipsychotics and falls and fractures.

Antipsychotics Rise in Youth, But Hospitalization Rates Stay the Same

Researchers from Tufts and Harvard find in a review of 233 medical charts of psychiatrically hospitalized youth at three points in time (1991, 1998...

Glucose Metabolism “Derangements” from Second Generation Antipsychotics Clarified

New Zealand and Chinese investigators believe they have clarified the mechanisms by which second generation antipsychotics cause serious "derangements" in glucose metabolism in the...

Antipsychotic Use Does Not Correlate With Conversion to Psychosis

Researchers in Brazil find, in a meta-analysis, that only 30% of youth deemed to be of ultra high risk of psychosis do in fact...

Pharmacology Gets More Cooperation Than Psychosocial Advice

In a study of conformance to evidence-based treatment recommendations at mental health clinics among people diagnosed with schizophrenia, Canadian researchers found that conformance to...

Non-Drug Therapies Outperform Drug Therapies in Preventing Relapse

In a study of 597 outpatients who were perceived as likely nonadherers to oral antipsychotic interventions, Spanish researchers found that relapse was lower in...

Cognitive Function Improved by Reducing Antipsychotics

A 28-week randomized controlled study by researchers in Japan, Canada and the United States finds that a 50% reduction of risperidone or olanzapine significantly...

Seroquel Abuse Rising, Along With Ambulance Calls

Australian researchers have uncovered an alarming increase of Seroquel-related ambulances calls. Rising prescriptions of of the drug along with its developing use as a drug...

Psychiatrists’ Prescriptions for First-time Psychosis Often Don’t Follow Guidelines

"Many patients with first-episode psychosis receive medications that do not comply with recommended guidelines for first-episode treatment," states a National Institute of Mental Health...

Disconnect Between Antipsychotic Prescribing and Metabolic Screening

Despite American Diabetes Association and APA recommendations of glucose and lipid testing for all patients started on antipsychotics, there is a disconnect between prescribing...

Antipsychotics do not Result in Neurocognitive Improvement

Researchers in London and Spain, in a prospective, randomized, study of long-term (3 year) effects of first- and second-generation antipsychotics on neurocognition in 79...

Nurses Confront the Myths of Psychiatric Drugs

The July issue of Nursing Ethics takes on the myths of psychiatric drugs, saying that "psychiatric drugs are used only to control ‘patient’ behaviour...

APA Recommends Reducing Antipsychotics for Children and Elderly Without Psychosis

The American Psychiatric Association, as part of the American Board of Internal Medicine's "Choosing Wisely" initiative, released new practice guidelines yesterday that advise against...

Scant Evidence for Combining Antipsychotics

Researchers in Barcelona, Spain retrospectively reviewed the use of antipsychotics in 117,811 patients, of whom 9,855 were given combinations of antipsychotics and 13,763 were...

Antipsychotics for Poor Kids Soar, Mostly for Behavior Problems

Cross-sectional analysis by the University of Maryland and Johns Hopkins University of 456,315 youths enrolled in Medicaid between 1997 and 2006 finds that the...

NMS in 2nd Gen. Antipsychotics: Similar, But Younger

A study released online today by the British Journal of Psychiatry shows that the clinical profile of neuroleptic malignant syndrome (NMS) is similar in 1st- v....

No Advantage for Second-Generation Antipsychotics

In a study of 720 consecutive hospital admissions in a specific catchment area from 1991 to 2005, researchers found that there was no difference...

Antipsychotics Increase Retrovirus Activity in Humans

Endogenous retroviruses, remnants of ancient infections that have become part of the human genome, have been associated with the development of schizophrenia. But researchers...

Multiple Medications Associated With Poorer Outcomes

Research from Germany finds that people with schizophrenia or schizoaffective diagnoses given multiple medications - an antipsychotic plus a benzodiazepine or more than one...

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