Antipsychotics

A new study has found a strong association between antipsychotic drugs and higher rates of severe cases of COVID-19.

In a recent interview, Nancy Andreasen, former editor-in-chief of the American Journal of Psychiatry, reaffirmed her earlier findings that antipsychotics shrink brain tissue. "We spent a couple...

There is a lack of consensus in the definition of ‘relapse’ across randomized controlled trials of antipsychotic maintenance treatment for schizophrenia and psychosis.

Review of a new mixed depression guideline reveals financial bias of guideline developers and lack of evidence supporting recommendations for prescribing of antipsychotics.

The July issue of Nursing Ethics takes on the myths of psychiatric drugs, saying that "psychiatric drugs are used only to control ‘patient’ behaviour...

A review of research on antipsychotic medications as an adjunctive treatment for depression published this week in PLoS Medicine finds that the widespread practice...

Researchers found some antipsychotics to be worse than others for causing sexual dysfunction.

In a study of 10,969 older patients treated with antipsychotics in Quebec, Canada, researchers found a 2.19 times greater risk of heart attack in...

A partnership designed to decrease antipsychotic use in elderly patients may have led to increased use of medications with even worse risk/benefit profiles.

A review of all research on the use of antipsychotics for the treatment of anorexia nervosa found no demonstrable efficacy in terms of body...

Although cocaine and psychostimulant dependence are thought to be related to increased dopamine release, research from Tokyo and Long Island finds that the effect...

One-third of adults with an intellectual or developmental disability are dispensed antipsychotics, despite having no existing psychiatric diagnosis.

Elderly people in Sweden are five times more likely to be taking antipsychotics if they have a diagnosis of dementia, according to research published in Acta Psychiatrica Scandinavica. And among those people with dementia, the lower their education the higher the likelihood they’re taking antipsychotics.

A new study published this month in the journal Neuron identifies the mechanism by which antipsychotic drugs can induce parkinsonism, a condition involving movement...

The percentage of seniors in the United States prescribed potentially deadly antipsychotic drugs increases with age. A new study reveals that in the face of serious risks of strokes, fractures, kidney injuries, and death, over seventy-five percent of seniors given antipsychotics do not have a diagnosis for a mental disorder.

Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

Three independent studies in two journals reported strong links between antipsychotics and falls and fractures.

Nearly 90,000 American adults are going to emergency rooms every year in response to adverse events from psychiatric medications, according to a study in...

A team of psychiatrists reviewed 654 cases in West Ireland to find that nearly 1% of all patients taking the antipsychotic clozapine had experienced clozapine-induced stuttering.

Researchers from the City College of New York and Columbia University published a study this month testing the hypothesis that people diagnosed with schizophrenia treated long-term with antipsychotic drugs have worse outcomes than patients with no exposure to these drugs. They concluded that there is not a sufficient evidence base for the standard practice of long-term use of antipsychotic medications.

A study published today in the American Medical Association's journal JAMA Psychiatry reports that patients whose antipsychotic treatment was reduced or discontinued (DR) experienced a recovery...

"Pathological gambling, hypersexuality, compulsive shopping and other impulse control disorders were associated with the use of dopamine receptor agonists, often prescribed for Parkinson’s disease,...

A 28-week randomized controlled study by researchers in Japan, Canada and the United States finds that a 50% reduction of risperidone or olanzapine significantly...

Antipsychotic medications that are commonly being used to help control behaviors in elderly people with dementia seem to be causing premature deaths at high rates.

Despite American Diabetes Association and APA recommendations of glucose and lipid testing for all patients started on antipsychotics, there is a disconnect between prescribing...