Antidepressant Use Associated With Menstruation Disorders

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In a study of 793 women taking antidepressants and 639 not taking them, researchers in Turkey found that menstruation disorders were significantly associated with...

Most Cases of Tardive Dyskinesia are Permanent

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Only one out eight patients, out of 108 with tardive dyskinesia, recovered from the disorder in an Emory University Movement Disorders Clinic study. The...

Long-Term Benzos Worsen Anxiety

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Long-term use of benzodiazepines for anxiety remains a widespread, despite guidelines that recommend against it, according to a roundtable discussion at the annual conference of...

Prescription Drugs May Cause One Third of All Birth Defects

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Up to a third of all birth defects may be linked to prescription drugs, according to a review of the evidence published in The...

Benzos Fail to Prevent, May Increase PTSD

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In a review of the evidence regarding benzodiazepines, researchers from the University of Michigan find that benzodiazepines used in the treatment of PTSD are...

SSRIs: More Harm Than Good

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Beginning with an "evolutionary analysis" and a review of serotonin's role in the body, researchers from Canada and the U.S. conduct a thorough review...

Publication Bias in Literature on Antidepressants for Autism

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Researchers at the University of Michigan reviewed published and unpublished trials of serotonin receptor inhibitors (SRI) for the treatment of autism spectrum disorders (ASD)....

Schizophrenia Prevents Cancer; Antipsychotics May Cause It

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In a review of all 59,233 individuals diagnosed with schizophrenia in Sweden between 1965 and 2008, researchers from Sweden and the U.S. identified 6137...

Do Benzos Deserve a Major Role in the Treatment of Psychiatric Disorders?

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Researchers at the University of Milan and King's College, London thoroughly reviewed the literature available on Medline and Cochrane regarding the use of benzodiazepines...

Pharmacological Treatment of Schizophrenia: a Fifty-Year Review

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Researchers in the U.S. and India reviewed the pharmacological treatment of schizophrenia since its introduction 50 years ago, trying to understand why it "remains...

Minimal Empirical Support for Antidepressant Treatment in Young People

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Researchers from Australia reviewed the existing literature for good-quality evidence of effective prevention and treatment of depression in young people. Prevention research was dominated...

SSRIs Significantly Increase Falls in Dementia, Even at Low Doses

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Researchers in the Netherlands followed 248 nursing home residents with dementia for two years, finding that even 25% of the defined daily dose of...

Multiple Medications Associated With Poorer Outcomes

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Research from Germany finds that people with schizophrenia or schizoaffective diagnoses given multiple medications - an antipsychotic plus a benzodiazepine or more than one...

Benzodiazepine & SSRI Addiction and Withdrawal

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The May issue of Addiction includes a review of pharmacological and phenomenological issues around benzodiazepine (BZD) and SSRI discontinuation.  Definitions, perceptions and management of the...

Study of Antidepressants and Suicide is Retracted

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A controversial 2010 paper, "Antidepressant Medication Prevents Suicide in Depression", has been retracted by Acta Psychiatrica Scandinavica. In a contemporaneous issue of British Journal of...

No Advantage for Second-Generation Antipsychotics

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In a study of 720 consecutive hospital admissions in a specific catchment area from 1991 to 2005, researchers found that there was no difference...

Prenatal Antipsychotic Exposure Causes Neuromotor Deficits

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Researchers studying 309 6-month-olds at Emory University's Infant Development Laboratory found that infants prenatally exposed to antipsychotics showed significantly lower scores on a standardized...

Antidepressants and Advertising: Psychopharmaceuticals in Crisis

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An article by written by faculty of the Harvard History of Science Department and the Program in Placebo Studies explores how "drug marketing portrays...

Antipsychotics Increase Risk of Heart Attack in the Elderly

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In a study of 10,969 older patients treated with antipsychotics in Quebec, Canada, researchers found a 2.19 times greater risk of heart attack in...

Antidepressants, Not Depression, Raise Risk of Preeclampsia in Pregnancy

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In a study of 69,448 pregnant women with depression, researchers from the Harvard school of public health found that use of SSRI (selective serotonin...

Second-Generation Antipsychotics Just as Likely as Older Drugs to Cause EPS

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In a study of an earlier randomized controlled trial of antipsychotics, researchers from Yale and the U.K found that second-generation antipsychotics were as likely...

Psychiatric Drugs, Especially Antipsychotics, Contribute to Increasing Drug Costs

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Antipsychotics have overtaken antidepressants as the most costly class of psychiatric medication in England, according to a study by Stephen Ilyas and Joanna Moncrieff...

Hypertension in Pregnancy 50% More Likely With SSRIs

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Researchers in Montreal found in a sample of 1,216 pregnant women that those who used antidepressants were at least 50% more likely to experience...

Living Alone Nearly Doubles Antidepressant Use

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Finnish researchers found that in a study of 3471 men and women, those living alone were almost twice as likely to use an antidepressant....

Contribution of Antipsychotics to Suicidality and Depression

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Peter Lehmann reviews the contribution of antipsychotics to suicide and depression in schizophrenia in the current International Journal of Psychotherapy.  Publications about the intrinsic effects of...