Multiple Medications Associated With Poorer Outcomes

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Research from Germany finds that people with schizophrenia or schizoaffective diagnoses given multiple medications - an antipsychotic plus a benzodiazepine or more than one...

Benzodiazepine & SSRI Addiction and Withdrawal

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The May issue of Addiction includes a review of pharmacological and phenomenological issues around benzodiazepine (BZD) and SSRI discontinuation.  Definitions, perceptions and management of the...

Study of Antidepressants and Suicide is Retracted

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A controversial 2010 paper, "Antidepressant Medication Prevents Suicide in Depression", has been retracted by Acta Psychiatrica Scandinavica. In a contemporaneous issue of British Journal of...

No Advantage for Second-Generation Antipsychotics

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In a study of 720 consecutive hospital admissions in a specific catchment area from 1991 to 2005, researchers found that there was no difference...

Prenatal Antipsychotic Exposure Causes Neuromotor Deficits

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Researchers studying 309 6-month-olds at Emory University's Infant Development Laboratory found that infants prenatally exposed to antipsychotics showed significantly lower scores on a standardized...

Antidepressants and Advertising: Psychopharmaceuticals in Crisis

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An article by written by faculty of the Harvard History of Science Department and the Program in Placebo Studies explores how "drug marketing portrays...

Antipsychotics Increase Risk of Heart Attack in the Elderly

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In a study of 10,969 older patients treated with antipsychotics in Quebec, Canada, researchers found a 2.19 times greater risk of heart attack in...

Antidepressants, Not Depression, Raise Risk of Preeclampsia in Pregnancy

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In a study of 69,448 pregnant women with depression, researchers from the Harvard school of public health found that use of SSRI (selective serotonin...

Second-Generation Antipsychotics Just as Likely as Older Drugs to Cause EPS

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In a study of an earlier randomized controlled trial of antipsychotics, researchers from Yale and the U.K found that second-generation antipsychotics were as likely...

Psychiatric Drugs, Especially Antipsychotics, Contribute to Increasing Drug Costs

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Antipsychotics have overtaken antidepressants as the most costly class of psychiatric medication in England, according to a study by Stephen Ilyas and Joanna Moncrieff...

Hypertension in Pregnancy 50% More Likely With SSRIs

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Researchers in Montreal found in a sample of 1,216 pregnant women that those who used antidepressants were at least 50% more likely to experience...

Living Alone Nearly Doubles Antidepressant Use

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Finnish researchers found that in a study of 3471 men and women, those living alone were almost twice as likely to use an antidepressant....

Contribution of Antipsychotics to Suicidality and Depression

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Peter Lehmann reviews the contribution of antipsychotics to suicide and depression in schizophrenia in the current International Journal of Psychotherapy.  Publications about the intrinsic effects of...

Seroquel Abuse Rising, Along With Ambulance Calls

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Australian researchers have uncovered an alarming increase of Seroquel-related ambulances calls. Rising prescriptions of of the drug along with its developing use as a drug...

High Cost to Medicaid Programs For Off-Label Use of Antipsychotics

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A study of 42 state Medicaid programs found that 58% of prescriptions for antipsychotics  were not for schizophrenia or bipolar disorder. Off-label prescribing was most prevalent...

45% of Children and Adolescent Inpatients Prescribed Antipsychotics

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In a rare long-term study of antipsychotics used in children and adolescent inpatients, the Institute of Living in Hartford, CT followed 3,851 consecutive admissions...

Ritalin Impairs Learning and Memory

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Ritalin reduced impulsive responses and increased the amount of time willing to stay on task of Rhesus monkeys in a study from the University...

Women on SSRIs Less Likely To Breastfeed

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In a prospective cohort study of 466 pregnant women over 10 years, researchers at the California Teratogen Information Service found that women exposed to...

Activity-Based Therapies Reduce Antipsychotic Use

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Researchers from the University of North Carolina found that activity-based therapy and care reduced the use of antipsychotics in a study of 107 people...

Overprescribing of Benzodiazepines

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Norwegian researchers found that 14.6% (27,861) of patients who were prescribed benzodiazepines used two simultaneously, despite the fact that all benzodiazepines have essentially the...

Brain Volume Recovers With Remission, Not With Medication

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In a prospective study of 28 outpatients with major depression, Canadian researchers investigated whether brain volume changes stabilized with antidepressant treatment and/or reversed with...

WHO Says Newer Antipsychotics Most Costly, Least Effective Strategy

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In an analysis of neuropsychiatric conditions in sub-Saharan Africa and South East Asia, the World Health Organization found that inpatient treatment of schizophrenia with...

ADHD Overtreated in Relatively Younger Children

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An 11-year study of 937,943 children in British Columbia found that boys who were relatively younger than their classmates were 41% more likely to...

SSRIs Cause Delayed Head Growth and Premature Birth

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In a study of 7,696 pregnant women, researchers in the Netherlands and the U.S. found that SSRIs caused slower head growth and premature birth....

Rise of Antipsychotics in Children

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Researchers at Johns Hopkins explore the use of antipsychotics in children, finding a dramatic rise in off-label prescribing with little oversight or research into...