Benzo Discontinuation Improves Quality of Life and Reduces Symptoms of Schizophrenia

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Researchers in Japan find that tapering or reducing benzodiazepines has a positive effect on quality of life, verbal and working memory, and psychiatric symptoms...

Non-Drug Therapies Outperform Drug Therapies in Preventing Relapse

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In a study of 597 outpatients who were perceived as likely nonadherers to oral antipsychotic interventions, Spanish researchers found that relapse was lower in...

Antidepressants Have No Effect On Bipolar Depression

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In a review of 68 articles published between 2005 and 2011, Israeli researchers found that most well-controlled studies failed to show a significant effect of...

Antipsychotic Use Does Not Correlate With Conversion to Psychosis

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Researchers in Brazil find, in a meta-analysis, that only 30% of youth deemed to be of ultra high risk of psychosis do in fact...

Suicidal Thoughts and Behavior With Antidepressant Treatment: A Reanalysis

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In 2004 and 2006, the FDA concluded that SSRI antidepressants increased the risk of suicidal ideation in children and adolescents. However, in this month's...

Assessing Increased Mortality Risks of Antipsychotics and Mood Stabilizers in Dementia

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An article in January's American Journal of Psychiatry weighs the relative risk of mortality associated with various antipsychotics and mood stabilizers used in the treatment of...

Medications May Add to Mortality Rate in Schizophrenia

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Dutch researchers write in the Journal of Clinical Psychopharmacology that, in a prospective study of 7415 persons with diagnoses of schizophrenia, use of a first-generation...

Antidepressants Increase Suicide Risk in Children and Adolescents

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In a meta-analysis of studies of 6039 individuals, researchers in the UK determined that, consistent with previous meta-analysses, antidepressants increased "suicide-related outcomes."  Read more    ...

Discontinuing Psychotropics Reduces Falls in Elderly

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Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

Antipsychotics Increase Retrovirus Activity in Humans

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Endogenous retroviruses, remnants of ancient infections that have become part of the human genome, have been associated with the development of schizophrenia. But researchers...

Alarm About Antipsychotics as Sleep Aids

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Canadian sleep researchers, writing in The Lancet, warn that weight gain, lipid and glucose dysregulation, restless leg syndrome, sleep-walking and eating while asleep, and...