Study Highlights Difficulty of Antipsychotic Withdrawal

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New research finds insomnia, anxiety, and depression are common symptoms of antipsychotic withdrawal, highlighting difficulties of discontinuation.

Common Side Effects Leading to Antidepressant Discontinuation

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New research finds the negative drug effects most commonly associated with initiating antidepressant discontinuation are anxiety, suicidal thoughts, vomiting, and rashes.
Pattern of blue and yellow pills or tablets on a pink background. concept of medicine, pharmacy and coronavirus. copy space

SSRI Withdrawal has Social, Cognitive, and Emotional Consequences

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New research finds that the non-physical aspects of withdrawal from SSRIs are often overlooked.

Mental Health Staff Reluctant to Support Service Users in Tapering Antipsychotics, Study Finds

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Study reveals schizophrenia patients find little support from mental health staff in reducing side effects-heavy drugs.
The young patient at the reception in the hospital

Patients Express Anger at Doctors’ Ignorance About Antidepressant Withdrawal Effects

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Antidepressant users share their frustrations towards a healthcare system that overprescribes but is ill-equipped to support with discontinuation and withdrawal symptoms.

Hyperbolic Tapering off Antidepressants Limits Withdrawal

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New research by Jim van Os and Peter Groot finds that using hyperbolic tapering to discontinue antidepressants reduces withdrawal effects.

Prescribers Often Fail to Support Patients Discontinuing Antidepressants, Study Finds

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Study reveals most patients are dissatisfied with prescribers' support when discontinuing antidepressants.

Global Survey Leads to New Recommendations for Deprescribing Psychiatric Drugs

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Growing rates of long-term psychiatric drug prescriptions and documented issues with withdrawal demonstrate a need for safe deprescribing practices.

New Guidance on Antidepressant Withdrawal for Doctors in the UK

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New guidance for primary care doctors in the UK on antidepressant discontinuation acknowledges severe and long-lasting withdrawal symptoms.

Researchers Seek Standardized and Safe Antidepressant Tapering Protocol

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A new study promotes the use of a standardized approach to antidepressant tapering.

Gradual Tapering Recommended for Antidepressant Discontinuation

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A new literature review reinforces the need to “down-titrate” or taper antidepressants, especially drugs like Celexa and Paxil.

Antidepressant Withdrawal Linked to Suicide Attempt in Case Study

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Researchers suggest that antidepressant withdrawal can be a possible precipitant of suicide.

Research Explores the Experience of Benzodiazepine Withdrawal

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A new study reveals many benzodiazepine users are misinformed about the risks of withdrawal and experience devastating consequences.

How to Distinguish Antidepressant Withdrawal from Relapse

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Mark Horowitz and David Taylor provide advice on how to tell the difference between antidepressant withdrawal and depression relapse.

Many Service Users Interested in Decreasing Antipsychotic Use with Professional Help

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New research examines service user attitudes on discontinuing and reducing antipsychotic drugs.
Girl, looking confused, holding pill bottle

Official Guidelines on Antidepressant Discontinuation Fail Practitioners and Patients

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A review of clinical practice guidelines for antidepressant discontinuation from across the English-speaking world reveals major pitfalls.
Doctor welcoming a patient

How Providers Can Support Psychiatric Drug Discontinuation

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Supportive patient-practitioner relationships are crucial to the successful discontinuation of psychiatric medication.
Picture of distressed man facing pills

What Helps Long-Term Users of Benzodiazepines and Z-Drugs Discontinue?

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Current long-term users of benzodiazepines and Z-drugs identify barriers and facilitators for discontinuation.

Withdrawal Symptoms Cloud Findings of Antidepressant “Relapse” Trial

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Leading researchers point out that a new antidepressant study in NEJM failed to account for withdrawal symptoms, casting doubt on the results.

Researchers Provide Guidance for Reducing and Stopping Psychiatric Drugs

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New guidance on how to taper and discontinue from psychiatric drugs from leading researchers Mark Horowitz and David Taylor.

New Rating Tool for Tapering Antidepressants and Antipsychotics

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Researchers developed a rating scale to better assess service users’ experiences tapering antidepressant and/or antipsychotic medication.

Tapered Antipsychotic Withdrawal Mitigates Risk of Psychotic Symptoms

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Research suggests that slowly tapering off an antipsychotic reduces the risk of withdrawal psychosis compared to abrupt discontinuation.

“Relapse” in Antidepressant Trials Likely Caused by Sudden Withdrawal

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A new study investigates how antidepressant withdrawal effects often get confounded with depression relapse in clinical trials.

Sudden Antipsychotic Withdrawal—Not Low Dose—Leads to Relapse

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A new article in Lancet Psychiatry debunks past studies claiming that those on low doses of antipsychotics are more likely to relapse.

Four Essential Studies on Antidepressant Withdrawal Every Prescriber Must Read

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A researcher and service user Stevie Lewis recounts her own experience with antidepressant withdrawal and what she wishes her doctors knew.