Wednesday, September 18, 2019

Opioid Use in Pregnancy Dangerous and Understudied

Nora Volkow, the director of the National Institute on Drug Abuse (NIDA), authored an editorial for BMJ this month warning that the opioid abuse epidemic could have dangerous consequences for pregnant women. While the effects of opioid exposure on the developing brain are yet unknown, research suggests that infants may suffer from withdrawal syndrome, nervous system defects, and impaired attachment with the mother.

Report Calls For Policy Changes In Response To Dependence and Withdrawal From Prescribed Drugs

Statistics from the UK reveal that prescriptions for painkillers and antidepressants continue to rise despite concerns over dependence and debilitating withdrawal effects. The British Medical Association (BMA) Board of Science has released a report that acknowledges changes to medical practice, research and policy necessary for addressing the dependence and withdrawal effects of benzodiazepines, opioids, and antidepressants.

Eli Lilly Defeats “Bellwether” Cymbalta Withdrawal Lawsuit

The Federal jury hearing the first of 5000 claims against Eli Lilly for hiding the risks of withdrawal symptoms associated with Cymbalta found that Lilly did not...

Lilly Faces First Week of “Bellwether” Cymbalta Withdrawal Lawsuit

Calling it “Poison,” plaintiff Claudia Herrera testified she would not have taken Eli Lilly's drug Cymbalta had she known the risks. Lilly hid the risks of...

Antipsychotic Dose Reduction Linked To Long-term Improvements In First-Episode Schizophrenia Patients

Careful reductions in dosage levels of antipsychotic medications over time improved long-term rates of recovery and functional remission in patients diagnosed with a first-episode psychosis.

More Discussion of Antidepressant Withdrawal Effects

-Forensic psychiatrist Andrew Shepherd reviews a recent study on withdrawal effects from coming off antidepressant drugs.

Antipsychotic-induced Sexual Dysfunction Underreported

Researchers found some antipsychotics to be worse than others for causing sexual dysfunction.

Lithium May Cause Sexual Dysfunction — More Research Needed

Lithium appears to reduce libido and sexual function, and more research into the problem is needed.

Antidepressant Caused Six-fold Artery Plaque Build-up in Monkeys

Zoloft caused up to six-fold increases in build-up of atherosclerosis plaque in the coronary arteries of monkeys.

PTSD and Antidepressants Linked to Diabetes

A JAMA Psychiatry study found links between PTSD, type 2 diabetes, and antidepressants.

Children on Antipsychotics 50% More Likely to Develop Diabetes

Antipsychotic drugs increased the risk of children developing diabetes by 50%, and with an antidepressant added, their risk doubled.

Pfizer Accused of Knowing Zoloft Antidepressant Caused Birth Defects

The first of more than 1,000 lawsuits about Zoloft and birth defects has gotten underway.

“Treatment Resistant” Schizophrenia Strongly Linked to Dopamine Supersensitivity

Over 70% of schizophrenia patients who are "treatment resistant" have apparently developed dopamine supersensitivity psychosis from long-term use of antipsychotic medications.

More Evidence Antidepressants Might Induce Sexual Dysfunction Even After Stopping Them

A retrospective study in the Journal of Clinical Psychiatry examined cases of people who suffered sexual dysfunction that endured even after stopping taking SSRI antidepressants.

Psychotropics During Pregnancy Raise Risk of Babies with Low Birth Weight, Hospitalizations

The use by mothers of any of four major classes of psychiatric medications during pregnancy significantly raises the risk that their babies will be born with low birth weights and will need to be hospitalized.

Researcher: 60,000 Americans Now Taking Antipsychotics Will Die Prematurely

-A fired government health economist says that his research was showing that 60,000 Americans now taking antipsychotic medications will die prematurely.

Health Canada Adds Suicide Warning to ADHD Medications

Stronger warnings on the risk of suicidal thoughts and behaviors are being incorporated into the prescribing information for ADHD drugs in Canada.

Long-term Use of Lithium Can Cause Kidney Failure

A third of patients who have taken the common psychiatric medication lithium for over ten years have developed "chronic renal failure" from the drug.

Some Common Psychiatric Medications Associated With Pneumonia

Pneumonia cases in the elderly are strongly associated with use of anticholinergic medications, including benzodiazepines and tricyclic antidepressants.

J&J Loses Case Over Risperdal Antipsychotic Causing Male Breast Growth

A jury decided Johnson & Johnson must pay a Philadelphia man $2.5 million in damages "for failing to warn that its Risperdal antipsychotic could cause gynecomastia."

Antidepressants Actually Reduce Serotonin Levels

Common scientific beliefs about serotonin levels in depression and how antidepressants act on the brain appear to be completely backwards.

Stopping SSRI Antidepressants Can Cause Long, Intense Withdrawal Problems

In the first systematic review of withdrawal problems that patients experience when trying to get off SSRI antidepressant medications, researchers found that withdrawing from SSRIs was comparable to trying to quit addictive benzodiazepines.

FDA System for Recording Adverse Drug Effects Perilously Deficient

The system that the US FDA is using to gather and report on information about dangerous side effects from medications is extremely unreliable and...

Over One Thousand Boys Grew Breasts “Probably” Caused By Common Psychiatric Medication

According to an ex-chief of the FDA, Johnson & Johnson knew long before it started warning people that Risperdal could cause boys to grow breasts.

Certain Antidepressants, Sleep Aids Associated with Higher Dementia Risk

Greater cumulative doses of drugs that are anticholinergic or block the neurotransmitter acetylcholine are associated with significant increases in dementia and Alzheimer's.

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