Friday, January 17, 2020

Half of First-Episode Patients Respond to Antipsychotics

No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.

Slew of New Studies Spot Links Between Psychiatric Medications and Bone Loss, Fractures

Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.

Acute Respiratory Failure More Likely in COPD Patients Prescribed Antipsychotics

Researchers recommend that healthcare professionals be vigilant regarding the signs of respiratory failure among patients with COPD who are receiving antipsychotics, especially during the initial treatment phase.

Scant Evidence for Combining Antipsychotics

Researchers in Barcelona, Spain retrospectively reviewed the use of antipsychotics in 117,811 patients, of whom 9,855 were given combinations of antipsychotics and 13,763 were...

Antipsychotics During Pregnancy Linked to Infant Problems

“Live, healthy babies are the most common outcome following the use of antipsychotic medication in pregnancy,” conclude Australian researchers in a study that was...

Children on Antipsychotics 50% More Likely to Develop Diabetes

Antipsychotic drugs increased the risk of children developing diabetes by 50%, and with an antidepressant added, their risk doubled.

45% of Children and Adolescent Inpatients Prescribed Antipsychotics

In a rare long-term study of antipsychotics used in children and adolescent inpatients, the Institute of Living in Hartford, CT followed 3,851 consecutive admissions...

Discussing The Meaning of Antipsychotics

Research published in the Journal of Psychiatric Practice finds that a "shared discussion of beliefs about medication between patient and care provider allows wider...

Study Shows Clozapine Can Result in Serious Gastrointestinal Complications

A large observational study published in CNS Drugs sheds light on serious adverse effects of the ‘gold standard’ antipsychotic Clozapine.

Psychiatry Defends Its Antipsychotics: A Case Study of Institutional Corruption

Jeffrey LIeberman and colleagues have published a paper in the American Journal of Psychiatry stating that there is no evidence that psychiatric drugs cause long-term harm, and that the evidence shows that these drugs provide a great benefit to patients. A close examination of their review reveals that it is a classic example of institutional corruption, which was meant to protect guild interests.

Antipsychotics Increase Retrovirus Activity in Humans

Endogenous retroviruses, remnants of ancient infections that have become part of the human genome, have been associated with the development of schizophrenia. But researchers...

Review Questions Long Term Use of Antipsychotics

Patients who recover from a single episode of psychosis are often prescribed antipsychotics long-term, despite a lack of evidence for this practice

Call to Monitor Adverse Effects of Antipsychotics in Youth

Researchers point to the risks of using antipsychotics with youth and caution against the practice.

More Time in Foster Care Linked to More Psychotropic Medicating

Children as young as four in foster care are taking three or more psychotropic medications, and the length of time that children aged six...

Antipsychotics Linked to Cognitive & Memory Impairments

Finnish reseachers report in Schizophrenia Research that antipsychotic use is associated with cognitive and memory impairments. The University of Oulu team studied forty people...

Long-Acting Risperidone (Consta) Increases Costs, Lowers Outcomes

Writing in the Journal of Clinical Psychiatry, researchers from the Health Economics Resource Center studied the effects of long-acting injectable risperidone (Consta) on 369 patients...

WHO Says Newer Antipsychotics Most Costly, Least Effective Strategy

In an analysis of neuropsychiatric conditions in sub-Saharan Africa and South East Asia, the World Health Organization found that inpatient treatment of schizophrenia with...

“Antipsychotic Use in Youth Without Psychosis: A Double-edged Sword”

This month’s issue of JAMA Psychiatry ran an editorial commenting on recent research revealing that the majority of youth prescribed antipsychotics have not been diagnosed with a mental disorder.

Anticholinergic Medications Linked to Dementia Similar to Early Alzheimer’s

A new study, published in the Journal of Clinical Psychiatry, investigates the effects of anticholinergic medications, such as antidepressants and antipsychotics, on cognition in older adults diagnosed with schizophrenia.

Pentagon Was Warned Off Antipsychotic for PTSD

Despite 2004 clinical guidelines issued by the Veterans' Administration that "there is insufficient evidence to recommend atypical antipsychotics for the treatment of PTSD,"  ...

Four Leading Antipsychotics Aren’t Safe or Effective in Older Adults

A 5-year study funded by the National Institute of Mental Health and conducted by U.C. San Diego School of Medicine, Stanford University and the...

Antipsychotics Aren’t Helpful to Children

Researchers from London, writing in European Psychiatry, reviewed "all RCTs involving children and young people with a diagnosis of childhood onset schizophrenia comparing any...

Antipsychotics Associated with High Risk of Death in Children

A new study has found that children and adolescents taking a high dose of antipsychotics are almost twice as likely to die of any cause than children on other types of medications.

Second-Generation Antipsychotics Just as Likely as Older Drugs to Cause EPS

In a study of an earlier randomized controlled trial of antipsychotics, researchers from Yale and the U.K found that second-generation antipsychotics were as likely...

Psychiatric Drugs, Especially Antipsychotics, Contribute to Increasing Drug Costs

Antipsychotics have overtaken antidepressants as the most costly class of psychiatric medication in England, according to a study by Stephen Ilyas and Joanna Moncrieff...

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