Friday, January 17, 2020

The Case Against Antipsychotics

This review of the scientific literature, stretching across six decades, makes the case that antipsychotics, over the long-term, do more harm than good. The drugs lower recovery rates and worsen functional outcomes over longer periods of time.

“Should We Stop Using Antipsychotic Medication?”

In a recent interview, Nancy Andreasen, former editor-in-chief of the American Journal of Psychiatry, reaffirmed her earlier findings that antipsychotics shrink brain tissue. "We spent a couple...

Patients Complain about Antipsychotic Medications Inducing “Zombie-like” State

People who take antipsychotic medications experience many side effects which have "major disruptive impact on their lives," according to research in the Journal of Mental Health Nursing.

Infants Exposed to Psychotropic Drugs During Pregnancy At Risk

New research published in the July issue of The Journal of Clinical Psychiatry found that the use of mood stabilizers, antipsychotics, antidepressants, and hypnotics during pregnancy is associated with increased health risks to the infant.

Antipsychotic Use Does Not Correlate With Conversion to Psychosis

Researchers in Brazil find, in a meta-analysis, that only 30% of youth deemed to be of ultra high risk of psychosis do in fact...

Experts Decry Dangerous Use of Antipsychotics in Children

In a featured article for Psychiatric Services, psychiatrists from Dartmouth raise the alarm on the increasing numbers of children prescribed dangerous antipsychotic drugs. Despite the fact that data on the safety of long-term use of these drugs in this vulnerable population “do not exist,” the rate of children and adolescents being prescribed antipsychotic drugs have continued to increase over the past fifteen years.

NMS in 2nd Gen. Antipsychotics: Similar, But Younger

A study released online today by the British Journal of Psychiatry shows that the clinical profile of neuroleptic malignant syndrome (NMS) is similar in 1st- v....

Anticholinergic Psychiatric Drugs Linked to a 50% Increase in Dementia

People who take anticholinergic drugs, such as antidepressants and antipsychotics, are at a 50% higher risk of dementia.

Antipsychotic Dose Reduction Linked To Long-term Improvements In First-Episode Schizophrenia Patients

Careful reductions in dosage levels of antipsychotic medications over time improved long-term rates of recovery and functional remission in patients diagnosed with a first-episode psychosis.

Researchers Struggle as Placebos Becoming More Effective & Antipsychotics Losing Power

Since the 1960s, the positive response rates to antipsychotic medications have been dropping steadily, according to a meta-analysis published in JAMA Psychiatry by Columbia...

Prenatal Antipsychotic Exposure Causes Neuromotor Deficits

Researchers studying 309 6-month-olds at Emory University's Infant Development Laboratory found that infants prenatally exposed to antipsychotics showed significantly lower scores on a standardized...

Baseline Lipid Monitoring with Antipsychotics “Disappointingly Low”

"Even in an academic setting with active discussions among psychiatrists regarding issues of metabolic risk ... baseline lipid monitoring is disappointingly low" according to...

Most Cases of Tardive Dyskinesia are Permanent

Only one out eight patients, out of 108 with tardive dyskinesia, recovered from the disorder in an Emory University Movement Disorders Clinic study. The...

Discontinuing Psychotropics Reduces Falls in Elderly

Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

FDA Warns About New Impulse-Control Problems Associated With Abilify

Yesterday, the US Food and Drug Administration (FDA) released a warning that the antipsychotic drug aripiprazole or Abilify is associated with compulsive and uncontrollable...

Antipsychotics Increase Mortality Risk in Patients with Parkinson’s Disease

A new study in JAMA Neurology finds that the use of antipsychotic drugs more than doubled the risk of death in patients with Parkinson’s...

Antipsychotics Increase Retrovirus Activity in Humans

Endogenous retroviruses, remnants of ancient infections that have become part of the human genome, have been associated with the development of schizophrenia. But researchers...

Clozapine-induced Stuttering Affects 1% Of Patients

A team of psychiatrists reviewed 654 cases in West Ireland to find that nearly 1% of all patients taking the antipsychotic clozapine had experienced clozapine-induced stuttering.

More Time in Foster Care Linked to More Psychotropic Medicating

Children as young as four in foster care are taking three or more psychotropic medications, and the length of time that children aged six...

WHO Says Newer Antipsychotics Most Costly, Least Effective Strategy

In an analysis of neuropsychiatric conditions in sub-Saharan Africa and South East Asia, the World Health Organization found that inpatient treatment of schizophrenia with...

Study Suggests Long-Term Antipsychotic Use May Result in Poorer Cognitive Functioning

Association found between long-term antipsychotic use and poorer performance on cognitive tasks in adults diagnosed with ‘schizophrenia.’

New Research Suggests Brain Abnormalities in ‘Schizophrenia’ May Result From Antipsychotics

Study finds that reduced cortical thickness and brain surface area associated with 'schizophrenia' may result from antipsychotic drug use.

Psychotropics During Pregnancy Raise Risk of Babies with Low Birth Weight, Hospitalizations

The use by mothers of any of four major classes of psychiatric medications during pregnancy significantly raises the risk that their babies will be born with low birth weights and will need to be hospitalized.

Patients on Antipsychotics at High Risk for Cardiovascular Issues, Study Finds

Antipsychotics present a known risk for major side effects. A new study suggests that certain antipsychotics may present a greater risk for cardiovascular disease than others.

Inappropriate Use of Antipsychotics on Adults with Intellectual and Developmental Disabilities

One-third of adults with an intellectual or developmental disability are dispensed antipsychotics, despite having no existing psychiatric diagnosis.

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