More Evidence Antipsychotics Reduce Brain Volume

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People diagnosed with schizophrenia experience reductions in brain volume that increase over time, and the amount of those reductions increases in proportion to the...

Antipsychotics do not Result in Neurocognitive Improvement

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Researchers in London and Spain, in a prospective, randomized, study of long-term (3 year) effects of first- and second-generation antipsychotics on neurocognition in 79...

Call to Monitor Adverse Effects of Antipsychotics in Youth

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Researchers point to the risks of using antipsychotics with youth and caution against the practice.

“Should We Stop Using Antipsychotic Medication?”

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In a recent interview, Nancy Andreasen, former editor-in-chief of the American Journal of Psychiatry, reaffirmed her earlier findings that antipsychotics shrink brain tissue. "We spent a couple...

A Short History of Tardive Dyskinesia: 65 Years of Drug-Induced Brain Damage That Rolls...

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Psychiatry has long turned a blind eye to the full scope of harm associated with TD. New TD drugs "work" by further impairing brain function.

“Antipsychotic Use in Youth Without Psychosis: A Double-edged Sword”

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This month’s issue of JAMA Psychiatry ran an editorial commenting on recent research revealing that the majority of youth prescribed antipsychotics have not been diagnosed with a mental disorder.

Slew of New Studies Spot Links Between Psychiatric Medications and Bone Loss, Fractures

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Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.

Does Longer Duration of Untreated Psychosis Cause Worse Outcomes?

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New research counters the long-held assumption that a longer duration of untreated psychosis is associated with worse outcomes.

Outcome Reporting Bias in Antipsychotic Medication Trials

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A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.

Less-impaired Youth Using Antipsychotics with Other Medications More Often

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Use of second-generation antipsychotics (SGA) alongside other medications is growing rapidly among youth who are less impaired, according to a study published online in...

Identifying Psychiatric Drugs Leading to Emergency Room Visits

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More than ten-percent of adults in the United States are currently prescribed at least one psychiatric medication but there is currently a lack of research on the prevalence of adverse drug events (ADEs) associated with these prescriptions outside of clinical trials.

Majority of Anorexia Patients are Prescribed Psychotropics Despite Lack of Data

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Research from the medical schools of Harvard University and the University of Melbourne, reported in the December International Journal of Eating Disorders, found that...

Antipsychotics Aren’t Helpful to Children

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Researchers from London, writing in European Psychiatry, reviewed "all RCTs involving children and young people with a diagnosis of childhood onset schizophrenia comparing any...

Psychiatrists’ Prescriptions for First-time Psychosis Often Don’t Follow Guidelines

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"Many patients with first-episode psychosis receive medications that do not comply with recommended guidelines for first-episode treatment," states a National Institute of Mental Health...

Family Economic Context Linked to Adolescents’ Antipsychotic Use

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In a study of the Swedish Medical Birth Registry published in the British Medical Journal, researchers identified all 324,510 single children born between 1988...

A Guide to Minimal Use of Neuroleptics

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This guide, by psychiatrists Volkmar Aderhold and Peter Stastny, provides a comprehensive review of antipsychotics and an evidence-based rationale for avoiding their use in first-episode psychosis, and for minimizing their long-term use.

WHO Says Newer Antipsychotics Most Costly, Least Effective Strategy

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In an analysis of neuropsychiatric conditions in sub-Saharan Africa and South East Asia, the World Health Organization found that inpatient treatment of schizophrenia with...

Discontinuing Psychotropics Reduces Falls in Elderly

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Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

NMS in 2nd Gen. Antipsychotics: Similar, But Younger

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A study released online today by the British Journal of Psychiatry shows that the clinical profile of neuroleptic malignant syndrome (NMS) is similar in 1st- v....

Better Recovery and Less Relapse Without Meds: A 20-Year Study

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Researchers at the University of Illinois College of Medicine found, in a 20-year prospective study of 139 psychotic patients, that patients had a far...

Patients Complain about Antipsychotic Medications Inducing “Zombie-like” State

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People who take antipsychotic medications experience many side effects which have "major disruptive impact on their lives," according to research in the Journal of Mental Health Nursing.

Antipsychotics Ineffective Against Cocaine, Stimulant Addictions

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Although cocaine and psychostimulant dependence are thought to be related to increased dopamine release, research from Tokyo and Long Island finds that the effect...

Antipsychotics Triple the Risk of Diabetes in Children and Youth

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Researchers from Vanderbilt and Columbia Universities and the FDA find that, through a retrospective cohort study of 28,858 patients of the Tennessee Medicaid program...
Doctor and patient

Barriers to Shared Decision Making in the Prescription of Antipsychotics

Researchers push for a renewed focus on true shared decision-making for patients diagnosed with psychosis.

Antipsychotic Drug Associated with Potentially Fatal Skin Rash

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The US Food and Drug Administration is warning the public that the antipsychotic medication ziprasidone "is associated with a rare but serious skin reaction...