Antipsychotics

This review of the scientific literature, stretching across six decades, makes the case that antipsychotics, over the long-term, do more harm than good. The drugs lower recovery rates and worsen functional outcomes over longer periods of time.

In a recent interview, Nancy Andreasen, former editor-in-chief of the American Journal of Psychiatry, reaffirmed her earlier findings that antipsychotics shrink brain tissue. "We spent a couple...

People who take antipsychotic medications experience many side effects which have "major disruptive impact on their lives," according to research in the Journal of Mental Health Nursing.

New research published in the July issue of The Journal of Clinical Psychiatry found that the use of mood stabilizers, antipsychotics, antidepressants, and hypnotics during pregnancy is associated with increased health risks to the infant.

Researchers in Brazil find, in a meta-analysis, that only 30% of youth deemed to be of ultra high risk of psychosis do in fact...

In a featured article for Psychiatric Services, psychiatrists from Dartmouth raise the alarm on the increasing numbers of children prescribed dangerous antipsychotic drugs. Despite the fact that data on the safety of long-term use of these drugs in this vulnerable population “do not exist,” the rate of children and adolescents being prescribed antipsychotic drugs have continued to increase over the past fifteen years.

A study released online today by the British Journal of Psychiatry shows that the clinical profile of neuroleptic malignant syndrome (NMS) is similar in 1st- v....

People who take anticholinergic drugs, such as antidepressants and antipsychotics, are at a 50% higher risk of dementia.

Careful reductions in dosage levels of antipsychotic medications over time improved long-term rates of recovery and functional remission in patients diagnosed with a first-episode psychosis.

Since the 1960s, the positive response rates to antipsychotic medications have been dropping steadily, according to a meta-analysis published in JAMA Psychiatry by Columbia...

Researchers studying 309 6-month-olds at Emory University's Infant Development Laboratory found that infants prenatally exposed to antipsychotics showed significantly lower scores on a standardized...

"Even in an academic setting with active discussions among psychiatrists regarding issues of metabolic risk ... baseline lipid monitoring is disappointingly low" according to...

Only one out eight patients, out of 108 with tardive dyskinesia, recovered from the disorder in an Emory University Movement Disorders Clinic study. The...

Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

Yesterday, the US Food and Drug Administration (FDA) released a warning that the antipsychotic drug aripiprazole or Abilify is associated with compulsive and uncontrollable...

A new study in JAMA Neurology finds that the use of antipsychotic drugs more than doubled the risk of death in patients with Parkinson’s...

Endogenous retroviruses, remnants of ancient infections that have become part of the human genome, have been associated with the development of schizophrenia. But researchers...

A team of psychiatrists reviewed 654 cases in West Ireland to find that nearly 1% of all patients taking the antipsychotic clozapine had experienced clozapine-induced stuttering.

Children as young as four in foster care are taking three or more psychotropic medications, and the length of time that children aged six...

In an analysis of neuropsychiatric conditions in sub-Saharan Africa and South East Asia, the World Health Organization found that inpatient treatment of schizophrenia with...

Association found between long-term antipsychotic use and poorer performance on cognitive tasks in adults diagnosed with ‘schizophrenia.’

Study finds that reduced cortical thickness and brain surface area associated with 'schizophrenia' may result from antipsychotic drug use.

The use by mothers of any of four major classes of psychiatric medications during pregnancy significantly raises the risk that their babies will be born with low birth weights and will need to be hospitalized.

Antipsychotics present a known risk for major side effects. A new study suggests that certain antipsychotics may present a greater risk for cardiovascular disease than others.

One-third of adults with an intellectual or developmental disability are dispensed antipsychotics, despite having no existing psychiatric diagnosis.