Monday, February 17, 2020

Four Leading Antipsychotics Aren’t Safe or Effective in Older Adults

A 5-year study funded by the National Institute of Mental Health and conducted by U.C. San Diego School of Medicine, Stanford University and the...

NMS in 2nd Gen. Antipsychotics: Similar, But Younger

A study released online today by the British Journal of Psychiatry shows that the clinical profile of neuroleptic malignant syndrome (NMS) is similar in 1st- v....

A Guide to Minimal Use of Neuroleptics

This guide, by psychiatrists Volkmar Aderhold and Peter Stastny, provides a comprehensive review of antipsychotics and an evidence-based rationale for avoiding their use in first-episode psychosis, and for minimizing their long-term use.

Elderly With Dementia can be Withdrawn From Antipsychotics

The Cochrane Library reports that "many older people with Alzheimer's dementia and NPS (neuropsychiatric symptoms) can be withdrawn from chronic antipsychotic medication without detrimental effects...

Smoking Cessation and Psychiatric Drugs Cause the Most Suicidal and Homicidal Reactions

The popular smoking cessation drug Chantix is the medication that most frequently makes people feel suicidal or homicidal, according to figures gathered by the...

Pentagon Was Warned Off Antipsychotic for PTSD

Despite 2004 clinical guidelines issued by the Veterans' Administration that "there is insufficient evidence to recommend atypical antipsychotics for the treatment of PTSD,"  ...

Antipsychotics Not Helpful for Anorexia

A review of all research on the use of antipsychotics for the treatment of anorexia nervosa found no demonstrable efficacy in terms of body...

Antipsychotics Even Riskier For The Elderly Than Previously Thought

Antipsychotic medications that are commonly being used to help control behaviors in elderly people with dementia seem to be causing premature deaths at high rates.

Drug Treatment for Borderline Personality Disorder Not Supported By Evidence

New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”

Children on Antipsychotics 50% More Likely to Develop Diabetes

Antipsychotic drugs increased the risk of children developing diabetes by 50%, and with an antidepressant added, their risk doubled.

Antipsychotics for Dementia: Not Justified and Risky

In a study of antipsychotics used to treat 75,445 patients in nursing homes in the United States, researchers from Harvard Medical School, Columbia and...

Patients on Antipsychotics at High Risk for Cardiovascular Issues, Study Finds

Antipsychotics present a known risk for major side effects. A new study suggests that certain antipsychotics may present a greater risk for cardiovascular disease than others.

Antipsychotics Associated with High Risk of Death in Children

A new study has found that children and adolescents taking a high dose of antipsychotics are almost twice as likely to die of any cause than children on other types of medications.

Discussing The Meaning of Antipsychotics

Research published in the Journal of Psychiatric Practice finds that a "shared discussion of beliefs about medication between patient and care provider allows wider...

Major Risks from Drug Interactions in Common Psychiatric Polypharmacy

It is very common for psychiatric patients, especially those diagnosed with schizophrenia, to be prescribed two or more psychiatric medications at once, and this...

Therapy Without Drugs May Ward Off Psychosis

A double-blind, randomized, placebo-controlled study comparing outcomes from risperidone, cognitive therapy, and supportive therapy in a cohort of 115 at-risk young adults over a...

Researchers Test Harms and Benefits of Long Term Antipsychotic Use

Researchers from the City College of New York and Columbia University published a study this month testing the hypothesis that people diagnosed with schizophrenia treated long-term with antipsychotic drugs have worse outcomes than patients with no exposure to these drugs. They concluded that there is not a sufficient evidence base for the standard practice of long-term use of antipsychotic medications.

How Exercise Can Help With First Episode Psychosis

New study examines the experiences of people utilizing an exercise program following a first-episode psychosis.

A History of Rapid Tranquilization

A paper by Joanna Moncrieff and Laura Allison in the journal History of Psychiatry reviews "the theory and practice of emergency sedation for behavioural...

Sexual Dysfunction from Antipsychotics Common — But Poorly Monitored by Physicians

Describing the prevalence and management of adverse effects from antipsychotics as "a neglected area" of study, a team of researchers from the UK has published a systematic review in the Journal of Psychopharmacology. They aimed to identify the prevalence of, and management strategies for nine categories of adverse effects, including sedation, weight gain, metabolic syndrome, sexual dysfunction and cardiovascular effects.

Adverse Reactions to Psychiatric Medications Hospitalize 17,000 Annually

Nearly 90,000 American adults are going to emergency rooms every year in response to adverse events from psychiatric medications, according to a study in...

Review Questions Long Term Use of Antipsychotics

Patients who recover from a single episode of psychosis are often prescribed antipsychotics long-term, despite a lack of evidence for this practice

Scientists Clarify Risks of Augmenting with Antipsychotic Medications for Depression

The researchers found that while antipsychotic drugs may be slightly more effective than alternative antidepressants, they come with a much higher side effect burden.

APA Recommends Reducing Antipsychotics for Children and Elderly Without Psychosis

The American Psychiatric Association, as part of the American Board of Internal Medicine's "Choosing Wisely" initiative, released new practice guidelines yesterday that advise against...

Antipsychotics Ineffective Against Cocaine, Stimulant Addictions

Although cocaine and psychostimulant dependence are thought to be related to increased dopamine release, research from Tokyo and Long Island finds that the effect...

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