Antipsychotics

According to researchers from Yale and the U.K., the improvements in extrapyramidal side effects expected from 2nd-generation antipsychotics has not been realized, while the...

A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.

Researchers in the U.S. and India reviewed the pharmacological treatment of schizophrenia since its introduction 50 years ago, trying to understand why it "remains...

Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.

A review of all research on the use of antipsychotics for the treatment of anorexia nervosa found no demonstrable efficacy in terms of body...

The US Food and Drug Administration is warning the public that the antipsychotic medication ziprasidone "is associated with a rare but serious skin reaction...

The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.

The popular smoking cessation drug Chantix is the medication that most frequently makes people feel suicidal or homicidal, according to figures gathered by the...

Research from London and Taipei finds that neuroleptic malignant syndrome (NMS) is associated with the number of different antipsychotics used (polypharmacy), rather than the overall...

Writing in Evidence Based Mental Health, researchers from Harvard Medical School and Massachusetts General Hospital found that use of medication for diabetes was significantly...

Researchers found some antipsychotics to be worse than others for causing sexual dysfunction.

A double-blind, randomized, placebo-controlled study comparing outcomes from risperidone, cognitive therapy, and supportive therapy in a cohort of 115 at-risk young adults over a...

In a study of 10,969 older patients treated with antipsychotics in Quebec, Canada, researchers found a 2.19 times greater risk of heart attack in...

Study finds that reduced cortical thickness and brain surface area associated with 'schizophrenia' may result from antipsychotic drug use.

Researchers at the University of Illinois College of Medicine found, in a 20-year prospective study of 139 psychotic patients, that patients had a far...

The researchers found that while antipsychotic drugs may be slightly more effective than alternative antidepressants, they come with a much higher side effect burden.

Researchers in Barcelona, Spain retrospectively reviewed the use of antipsychotics in 117,811 patients, of whom 9,855 were given combinations of antipsychotics and 13,763 were...

Researchers believe that side-effect monitoring is critical because of the increase in the use of antipsychotics

An article in JAMA Psychiatry advises very slow tapering for best results when discontinuing antipsychotic drugs.

Martin Harrow's study tracing the effects of antipsychotics on 139 schizophrenia (SZ) and mood-disordered patients over 20 years, just published in Psychological Medicine, finds...

Use of second-generation antipsychotics (SGA) alongside other medications is growing rapidly among youth who are less impaired, according to a study published online in...

A 5-year study funded by the National Institute of Mental Health and conducted by U.C. San Diego School of Medicine, Stanford University and the...

This review of the scientific literature, stretching across six decades, makes the case that antipsychotics, over the long-term, do more harm than good. The drugs lower recovery rates and worsen functional outcomes over longer periods of time.

Canadian researchers systematically reviewed all randomized controlled trials of second-generation antipsychotics (SGAs) and placebo in the treatment of disruptive behavior disorders in children, finding...

Large cohort study demonstrates that those with an intellectual disability are at an increased risk for movement disorder side effects of antipsychotics.