Osteoporosis Associated with Antipsychotic Treatment
Chinese researchers find, in a literature review for the International Journal of Endocrinology find an increased rate of osteoporosis among people with a schizophrenia...
Antipsychotic Medications Are Causing Obsessive Compulsive Disorders
Common second-generation antipsychotic medications are causing symptoms of obsessive-compulsive disorder to emerge in many people who previously only had schizophrenia symptoms, according to a...
Baseline Lipid Monitoring with Antipsychotics “Disappointingly Low”
"Even in an academic setting with active discussions among psychiatrists regarding issues of metabolic risk ... baseline lipid monitoring is disappointingly low" according to...
Vitamin B6 Effective in Reducing Antipsychotic Induced Akathisia
A recent RCT showed that vitamin B6 is as effective as propranolol for the treatment of akathisia.
“Janssen Accused of Withholding Data on Risperdal Side Effect in Autism”
MedPageToday reports that Janssen Pharmaceuticals omitted data from a 2003 study that connected Risperdal with serious side effects. Janssen was previously sued by the FDA for marketing Risperdal for off-label uses and settled for $2.2 billion in 2013. Earlier this year, a man with autism was awarded $2.5 million after growing breasts while on Risperdal. According to MedPage, documents from this latest case reveal missing data tables from a 2003 study “designed to ferret out potential adverse effects of long-term risperidone use.” The missing tables were related to elevated prolactin levels and side effects, including gynecomastia in men.
Antipsychotics Triple the Risk of Diabetes in Children and Youth
Researchers from Vanderbilt and Columbia Universities and the FDA find that, through a retrospective cohort study of 28,858 patients of the Tennessee Medicaid program...
Drug Treatment for Borderline Personality Disorder Not Supported By Evidence
New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”
Study Shows Clozapine Can Result in Serious Gastrointestinal Complications
A large observational study published in CNS Drugs sheds light on serious adverse effects of the ‘gold standard’ antipsychotic Clozapine.
Patients Complain about Antipsychotic Medications Inducing “Zombie-like” State
People who take antipsychotic medications experience many side effects which have "major disruptive impact on their lives," according to research in the Journal of Mental Health Nursing.
Study Explores Cognitive Effects of Antipsychotics
Reduced usage of antipsychotics in first-episode psychosis was associated with improved executive functioning.
Researchers Warn of “Brain Atrophy” in Children Prescribed Antipsychotics
Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.
Inappropriate Use of Antipsychotics on Adults with Intellectual and Developmental Disabilities
One-third of adults with an intellectual or developmental disability are dispensed antipsychotics, despite having no existing psychiatric diagnosis.
Study Links Prenatal Antipsychotic Exposure to Developmental Delays and ADHD
A comprehensive review indicates that children exposed to antipsychotics in the womb face an increased risk of ADHD and developmental delays.
Alarm About Antipsychotics as Sleep Aids
Canadian sleep researchers, writing in The Lancet, warn that weight gain, lipid and glucose dysregulation, restless leg syndrome, sleep-walking and eating while asleep, and...
45% of Children and Adolescent Inpatients Prescribed Antipsychotics
In a rare long-term study of antipsychotics used in children and adolescent inpatients, the Institute of Living in Hartford, CT followed 3,851 consecutive admissions...
Scientists Clarify Risks of Augmenting with Antipsychotic Medications for Depression
The researchers found that while antipsychotic drugs may be slightly more effective than alternative antidepressants, they come with a much higher side effect burden.
Researchers Struggle as Placebos Becoming More Effective & Antipsychotics Losing Power
Since the 1960s, the positive response rates to antipsychotic medications have been dropping steadily, according to a meta-analysis published in JAMA Psychiatry by Columbia...
Pentagon Was Warned Off Antipsychotic for PTSD
Despite 2004 clinical guidelines issued by the Veterans' Administration that "there is insufficient evidence to recommend atypical antipsychotics for the treatment of PTSD," ...
Disconnect Between Antipsychotic Prescribing and Metabolic Screening
Despite American Diabetes Association and APA recommendations of glucose and lipid testing for all patients started on antipsychotics, there is a disconnect between prescribing...
Risk of Death in the Elderly Trebled With Antipsychotics
In a nine-year study of all 2,224 residents of Leppävirta, Finland who were 65 years old or older, researchers found that the 332 residents...
Infants Exposed to Psychotropic Drugs During Pregnancy At Risk
New research published in the July issue of The Journal of Clinical Psychiatry found that the use of mood stabilizers, antipsychotics, antidepressants, and hypnotics during pregnancy is associated with increased health risks to the infant.
Antipsychotics Change the Architecture of the Colon
Researchers in Singapore find that antipsychotic medications are associated with changes to colonic architecture, which could result in difficult colonoscopy and increased colonoscopy-related risks....
Majority of Anorexia Patients are Prescribed Psychotropics Despite Lack of Data
Research from the medical schools of Harvard University and the University of Melbourne, reported in the December International Journal of Eating Disorders, found that...
Study Reduces Over-prescription of Antipsychotics in Older Adults
New intervention shows promise in reducing over-prescription of off-label antipsychotics in older adults.
Antipsychotics Not Helpful for Anorexia
A review of all research on the use of antipsychotics for the treatment of anorexia nervosa found no demonstrable efficacy in terms of body...