When Medication Changes More Than Symptoms: Antipsychotics’ Effect on Identity

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Recent research reveals how antipsychotic medications can significantly impact users' identity and self-image, challenging existing clinical approaches.

Mental Health Nurses Do Not Routinely Assess for Effects of Antipsychotic Medications

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Researchers believe that side-effect monitoring is critical because of the increase in the use of antipsychotics

Clozapine-induced Stuttering Affects 1% Of Patients

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A team of psychiatrists reviewed 654 cases in West Ireland to find that nearly 1% of all patients taking the antipsychotic clozapine had experienced clozapine-induced stuttering.

Breaking Blind: Antipsychotic Drug Efficacy May Be Overestimated

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Only 4 of 188 antipsychotic trials assessed blinding, and in all 4 cases, the blind was broken, potentially leading to an overestimation of the drug effect.

Antipsychotic Adherence Research Overlooks Key Information

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Researchers argue for a shift away from a focus on antipsychotic adherence toward understanding service users’ diverse patterns of use.

Half of First-Episode Patients Respond to Antipsychotics

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No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.

Some Avoid Antipsychotics Because They Value Psychosis

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Side effects, mistrust, stigma, forgetfulness and lack of insight have all been studied as reasons that up to 75% of people with a schizophrenia...

Increasing Use of Antipsychotics for Disruptive Behavior in Children

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Canadian researchers systematically reviewed all randomized controlled trials of second-generation antipsychotics (SGAs) and placebo in the treatment of disruptive behavior disorders in children, finding...

Industry Corruption in Systematic Review for Injectable Antipsychotics

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Researchers highlight how systematic reviews are compromised by pharmaceutical industry ties by exposing a study of injectable antipsychotics.

Common Parkinson’s Drugs Linked to Pathological Gambling and Hypersexuality

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"Pathological gambling, hypersexuality, compulsive shopping and other impulse control disorders were associated with the use of dopamine receptor agonists, often prescribed for Parkinson’s disease,...

Discussing The Meaning of Antipsychotics

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Research published in the Journal of Psychiatric Practice finds that a "shared discussion of beliefs about medication between patient and care provider allows wider...

Study Explores Cognitive Effects of Antipsychotics

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Reduced usage of antipsychotics in first-episode psychosis was associated with improved executive functioning.

Antipsychotics Increase Risk of Dementia; New Research Illuminates Why

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In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.

Psych Drugs May Increase Likelihood of Death in Schizophrenia

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The drugs, especially benzos and high doses of antipsychotics, led to an increased risk of death within five years. Antidepressants also did not reduce mortality.

“Should We Stop Using Antipsychotic Medication?”

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In a recent interview, Nancy Andreasen, former editor-in-chief of the American Journal of Psychiatry, reaffirmed her earlier findings that antipsychotics shrink brain tissue. "We spent a couple...

Exploding Myths About Schizophrenia: An Interview with Courtenay Harding

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The Vermont Longitudinal Study, led by Courtenay Harding, belied conventional beliefs about schizophrenia by showing remarkably good outcomes for patients discharged in the 1950s and '60s.

Researchers Struggle as Placebos Becoming More Effective & Antipsychotics Losing Power

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Since the 1960s, the positive response rates to antipsychotic medications have been dropping steadily, according to a meta-analysis published in JAMA Psychiatry by Columbia...

Off-Label Antipsychotic Use Among Children Soaring

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Researchers from Philadelphia and Baltimore find, in a study of Medicaid records for 50 states and the District of Columbia, that antipsychotic prescribing to...

Psychiatric Medication Use Associated with Triple the Risk of Stroke

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Common psychiatric medications double the risk of heart attack and triple the risk of stroke, according to research presented at the Canadian Cardiovascular Congress...

The Case Against Antipsychotics

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This review of the scientific literature, stretching across six decades, makes the case that antipsychotics, over the long-term, do more harm than good. The drugs lower recovery rates and worsen functional outcomes over longer periods of time.
Question mark inside a maze in the shape of human head.

New Study: The Clinical High Risk for Psychosis (CHR-P) Model Is Flawed

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The CHR-P model focuses on “attenuated psychosis” to predict “transition” to schizophrenia and ignores other factors. But new research shows that the model is a poor predictor.

NMS in 2nd Gen. Antipsychotics: Similar, But Younger

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A study released online today by the British Journal of Psychiatry shows that the clinical profile of neuroleptic malignant syndrome (NMS) is similar in 1st- v....
antipsychotic drugs

Antipsychotic Augmentation Increases Risk of Death

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A new study finds that adding an antipsychotic to existing antidepressant treatment is associated with a 45% increased risk of early death.

Call to Monitor Adverse Effects of Antipsychotics in Youth

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Researchers point to the risks of using antipsychotics with youth and caution against the practice.

Schizophrenia Prevents Cancer; Antipsychotics May Cause It

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In a review of all 59,233 individuals diagnosed with schizophrenia in Sweden between 1965 and 2008, researchers from Sweden and the U.S. identified 6137...