Outcome Reporting Bias in Antipsychotic Medication Trials

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A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.

APA Recommends Reducing Antipsychotics for Children and Elderly Without Psychosis

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The American Psychiatric Association, as part of the American Board of Internal Medicine's "Choosing Wisely" initiative, released new practice guidelines yesterday that advise against...

Patients on Antipsychotics at High Risk for Cardiovascular Issues, Study Finds

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Antipsychotics present a known risk for major side effects. A new study suggests that certain antipsychotics may present a greater risk for cardiovascular disease than others.

Antipsychotics During Pregnancy Linked to Infant Problems

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ā€œLive, healthy babies are the most common outcome following the use of antipsychotic medication in pregnancy,ā€ conclude Australian researchers in a study that was...

In Chronic Patients, Antipsychotics Have Limited Efficacy in Reducing Symptoms

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A large review and meta-analysis of 167 studies across 60 years dissects placebo-controlled randomized controlled trials of antipsychotic drugs.

Antipsychotic Risperidone Raises Risk of Male Breast Enlargement

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Taking the antipsychotic medication risperidone significantly increases men's chances of developing gynecomastia, or breast enlargement, according to a study by University of British Columbia...

Atypicals Associated with Diabetes in Adults Without Schizophrenia or Bipolar Diagnoses

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Writing in Evidence Based Mental Health, researchers from Harvard Medical School and Massachusetts General Hospital found that use of medication for diabetes was significantly...

Industry Corruption in Systematic Review for Injectable Antipsychotics

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Researchers highlight how systematic reviews are compromised by pharmaceutical industry ties by exposing a study of injectable antipsychotics.

Rise of Antipsychotics in Children

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Researchers at Johns Hopkins explore the use of antipsychotics in children, finding a dramatic rise in off-label prescribing with little oversight or research into...

Review Finds FDA Approval of Digital Antipsychotic Misguided

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The approval of the digital antipsychotic may open the door for more pharmaceutical company profits without evidence of benefits to patients.

How Do We Test the Effects of Long-Term Exposure to Antipsychotics?

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A new attempt to study the neurological effects of long-term exposure to antipsychotics uses healthy volunteers on minimal doses for 15 days.

Common Parkinson’s Drugs Linked to Pathological Gambling and Hypersexuality

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"Pathological gambling, hypersexuality, compulsive shopping and other impulse control disorders were associated with the use of dopamine receptor agonists, often prescribed for Parkinsonā€™s disease,...

Mental Health Nurses Do Not Routinely Assess for Effects of Antipsychotic Medications

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Researchers believe that side-effect monitoring is critical because of the increase in the use of antipsychotics

Antipsychotics for Anorexia: Weight Gain and Sedation as Treatment

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A study published online today (May 26, 2012) in Current Psychiatry Reports recommends Zyprexa as "elusive" pharmacologic solution to anorexia nervosa. On the basis...

Claims That Long-term Antipsychotic Use Leads to Better Outcomes are Misleading, Researchers Argue

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Researchers reveal the limitations and misleading interpretations of two recent studies that claim to demonstrate that long-term antipsychotic use leads to better outcomes.

Antipsychotics are Common for the Mechanically Ventilated

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Annals of Pharmacotherapy reports in a study of patients undergoing mechanical ventilation that 39% were given antipsychotic medication to prevent or treat delirium despite...

Antipsychotics Not Helpful for Anorexia

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A review of all research on the use of antipsychotics for the treatment of anorexia nervosa found no demonstrable efficacy in terms of body...

The BBC, Harrow, and a Public Left in the Dark

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The recent report by the BBC on medication-free treatment in Norway, when viewed in conjunction with the media silence on Martin Harrow's latest publication, reveals why the public remains misinformed about the long-term effects of antipsychotics.

Children on Antipsychotics 50% More Likely to Develop Diabetes

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Antipsychotic drugs increased the risk of children developing diabetes by 50%, and with an antidepressant added, their risk doubled.

Antipsychotics Increase Retrovirus Activity in Humans

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Endogenous retroviruses, remnants of ancient infections that have become part of the human genome, have been associated with the development of schizophrenia. But researchers...

Large Study Confirms Elevated Risk of Diabetes When Prescribed Antipsychotics

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A large longitudinal study finds once more that being prescribed antipsychotics significantly increases the risk of diabetes.

FDA Defends Decision to Approve Digital Aripiprazole

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Members of the U.S. Food and Drug Administrationā€™s Psychiatry Products division go on the defensive in a new article, responding to concerns about the agencyā€™s approval of digital aripiprazole.

Researchers Struggle as Placebos Becoming More Effective & Antipsychotics Losing Power

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Since the 1960s, the positive response rates to antipsychotic medications have been dropping steadily, according to a meta-analysis published in JAMA Psychiatry by Columbia...

Children Diagnosed with ADHD Younger are More Likely to get Multiple Medications

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New research demonstrates that children diagnosed with ADHD at younger ages are more likely than those diagnosed later to receive multiple medications within five years of their diagnosis.

Study Shows Clozapine Can Result in Serious Gastrointestinal Complications

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A large observational study published in CNS Drugs sheds light on serious adverse effects of the ā€˜gold standardā€™ antipsychotic Clozapine.