Science of Psychiatric Drugs

Off-Label Antipsychotic Use Among Children Soaring

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Researchers from Philadelphia and Baltimore find, in a study of Medicaid records for 50 states and the District of Columbia, that antipsychotic prescribing to...

Antipsychotic Drug Associated with Potentially Fatal Skin Rash

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The US Food and Drug Administration is warning the public that the antipsychotic medication ziprasidone "is associated with a rare but serious skin reaction...

Australia Reinforces Suicidality Warning on Strattera

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Australia's Therapeutic Goods Administration (TGA) has reinforced its warning to health professionals about the risk of suicidality associated with Straterra, after receiving reports of...

Antidepressants Not a ā€˜One Size Fits Allā€™ Solution, Researchers Find

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The largest ever study of the thoughts and reactions of antidepressant users reveals that many people have vastly different understandings and experiences of the...

Alberta Long-term Care Homes Reduce Antipsychotic Use by 50%

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The provincial government health service of Alberta, Canada recently concluded a successful pilot project that reduced the use of antipsychotic medications for patients with...

Benzo Discontinuation Improves Quality of Life and Reduces Symptoms of Schizophrenia

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Researchers in Japan find that tapering or reducing benzodiazepines has a positive effect on quality of life, verbal and working memory, and psychiatric symptoms...

SSRIs Can Impair New Learning About Anxiety

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Researchers from Columbia University and the New York State Psychiatric Institute test the behavioral effects of SSRIs on Pavlovian fear conditioning in rats, and...

Antipsychotics During Pregnancy Linked to Infant Problems

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ā€œLive, healthy babies are the most common outcome following the use of antipsychotic medication in pregnancy,ā€ conclude Australian researchers in a study that was...

Non-Drug Therapies Outperform Drug Therapies in Preventing Relapse

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In a study of 597 outpatients who were perceived as likely nonadherers to oral antipsychotic interventions, Spanish researchers found that relapse was lower in...

Benzos & Brain Tumors

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Researchers in Taiwan found a 3.33x greater risk of benign brain tumors in patients who had been prescribed benzodiazepines for at least 2 months....

SSRIs May Cause Bone Loss

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An Israeli study of 10,621 women found that those taking an SSRI more than 80% of the time were 1.4 times more likely to...

Majority of Anorexia Patients are Prescribed Psychotropics Despite Lack of Data

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Research from the medical schools of Harvard University and the University of Melbourne, reported in the December International Journal of Eating Disorders, found that...

Increased Risk of Preterm Birth in Women Taking Antidepressants

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A detailed meta-analysis of the published research on women taking antidepressants duringĀ pregnancyĀ finds that the rate of preterm birth is nearly doubled in the third...

Antidepressants Linked to Osteoporosis and Fractures

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Researchers from Switzerland, the U.K., Belgium, Denmark, Canada, Italy, Austria and the U.S. review the current evidence linking antidepressants to loss of bone mineral...

Quality of Relationship to Doctor Significantly Improves Antidepressant Efficacy

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The more that patients feel that they have a high-quality relationship with their prescribing physician, the more likely that they will regard their own responses to antidepressants as positive.

Women on SSRIs Less Likely To Breastfeed

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In a prospective cohort study of 466 pregnant women over 10 years, researchers at the California Teratogen Information Service found that women exposed to...

ADHD Stimulant Use Again Strongly Linked to School Accountability

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Wealthier children are more likely to take stimulants only during the school year and not during the summer, according to a study in American...

Antipsychotic Use Does Not Correlate With Conversion to Psychosis

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Researchers in Brazil find, in a meta-analysis, that only 30% of youth deemed to be of ultra high risk of psychosis do in fact...

Pentagon Was Warned Off Antipsychotic for PTSD

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Despite 2004 clinical guidelines issued by the Veterans' Administration that "there is insufficient evidence to recommend atypical antipsychotics for the treatment of PTSD," Ā ...

More Time in Foster Care Linked to More Psychotropic Medicating

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Children as young as four in foster care are taking three or more psychotropic medications, and the length of time that children aged six...

Psych Med Prescribing After Perinatal/Neonatal Death

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Research from MIA blogger Jeffrey Lacasse finds that "at present, there exists no rigorous evidence to support the prescription of Ads (antidepressants) in bereavement....

Common Parkinson’s Drugs Linked to Pathological Gambling and Hypersexuality

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"Pathological gambling, hypersexuality, compulsive shopping and other impulse control disorders were associated with the use of dopamine receptor agonists, often prescribed for Parkinsonā€™s disease,...

Antipsychotics for Poor Kids Soar, Mostly for Behavior Problems

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Cross-sectional analysis by the University of Maryland and Johns Hopkins University of 456,315 youths enrolled in Medicaid between 1997 and 2006 finds that the...

APA Recommends Reducing Antipsychotics for Children and Elderly Without Psychosis

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The American Psychiatric Association, as part of the American Board of Internal Medicine's "Choosing Wisely" initiative, released new practice guidelines yesterday that advise against...

Most Direct-to-Consumer Drug Advertisements Do Not Adhere to FDA Guidelines

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Few DTC drug advertisements fully adhere to FDA guidelines, the overall quality of information provided in DTC advertisements is low, and some advertisements market off-label indications.