Science of Psychiatric Drugs

Information on PRN Medication Practices is Lacking

The authors of an article in Journal of Psychosocial Nursing reviewed the literature on psychotropic PRN medications in order to respond to a request to...

Prescription Drugs May Cause One Third of All Birth Defects

Up to a third of all birth defects may be linked to prescription drugs, according to a review of the evidence published in The...

Antidepressant is Toxic to Fungus

Zoloft isn't just for depression any more; it also kills fungal meningitis. Researchers from Texas A&M find that "The problem for many current antifungal...

Psychiatric Medication Use Associated with Triple the Risk of Stroke

Common psychiatric medications double the risk of heart attack and triple the risk of stroke, according to research presented at the Canadian Cardiovascular Congress...

Hypertension in Pregnancy 50% More Likely With SSRIs

Researchers in Montreal found in a sample of 1,216 pregnant women that those who used antidepressants were at least 50% more likely to experience...

Multiple Medications Associated With Poorer Outcomes

Research from Germany finds that people with schizophrenia or schizoaffective diagnoses given multiple medications - an antipsychotic plus a benzodiazepine or more than one...

Antidepressants Associated with Preterm Birth, Infant Convulsions

A study of 228,876 pregnancies, published in the July issue of the American journal of Obstetrics & Gynecology, finds that maternal antidepressant use is...

20-Year Data Show Antipsychotics Do Not Reduce Psychosis

Martin Harrow's study tracing the effects of antipsychotics on 139 schizophrenia (SZ) and mood-disordered patients over 20 years, just published in Psychological Medicine, finds...

US Government Reviews Antidepressants During and After Pregnancy

The U.S. Department of Health and Human Services’ Agency for Healthcare Research and Quality has released a meta-analysis “Evidence Report” of the studies into...

Anticonvulsant Implicated in Birth Defects in up to 4,100 Children, French Study Finds

Between 2,150 and 4,100 children suffered from severe malformations connected to valproate prescription.

SSRI Antidepressants Appear to Raise Risk of Serious Respiratory Disease in Newborns

A new study has reinforced earlier warnings that taking SSRI antidepressants late in pregnancy appears to put mothers at a slightly increased risk of having newborns with persistent pulmonary hypertension.

Researchers Discover How Antipsychotics Lead To Parkinsonism

A new study published this month in the journal Neuron identifies the mechanism by which antipsychotic drugs can induce parkinsonism, a condition involving movement...

Guidelines Recommending Antidepressants “in Contradiction with the Current Evidence”

Researchers critique the German S3 guidelines for depression promoting antidepressants.

Antipsychotics Rise in Youth, But Hospitalization Rates Stay the Same

Researchers from Tufts and Harvard find in a review of 233 medical charts of psychiatrically hospitalized youth at three points in time (1991, 1998...

Elderly With Dementia can be Withdrawn From Antipsychotics

The Cochrane Library reports that "many older people with Alzheimer's dementia and NPS (neuropsychiatric symptoms) can be withdrawn from chronic antipsychotic medication without detrimental effects...

Pharmacological Treatment of Schizophrenia: a Fifty-Year Review

Researchers in the U.S. and India reviewed the pharmacological treatment of schizophrenia since its introduction 50 years ago, trying to understand why it "remains...

Antidepressants Are Not More Effective for Severe Depression, Study Finds

A new study, published in Acta Psychiatrica Scandinavica, found that antidepressant efficacy was not dependent on severity.

Antidepressants Cause Autism-Like Gene Expression in Fish

Prozac, Effexor, and/or carbamazepine induce gene expression patterns in the brains of fathead minnows that mimic those thought to be associated with autism in...

Women on SSRIs Less Likely To Breastfeed

In a prospective cohort study of 466 pregnant women over 10 years, researchers at the California Teratogen Information Service found that women exposed to...

11% of U.S. on Antidepressants: Less than 1/2 See a Mental Health Professional

Data from the National Health and Nutrition Examination Surveys (2005-2008) show that 11% of Americans 12 and over take antidepressants. 60% of those have...

2X Risk of Postpartum Hemorrhage Antidepressants

A study of 106,000 pregnant women with a diagnosis of mood or anxiety disorder, by researchers from Harvard, Duke, Michigan State and the university...

Antipsychotics During Pregnancy Raise Diabetes Risk

Swedish researchers find, in a study of all women giving birth in Sweden from July 1, 2005 through December 31, 2009 that those taking...

Parents’ Goals Affect Choice of Medication vs. Behavior Therapy

Researchers find that parents who are focused on their child's academic achievement are twice as likely to start the child on ADHD medications as...

Antipsychotics Not Helpful for Anorexia

A review of all research on the use of antipsychotics for the treatment of anorexia nervosa found no demonstrable efficacy in terms of body...

High Doses of Antidepressants Increase Self-Harm in Children, Young Adults

A comprehensive meta-analysis of randomized trial data by researchers from the Harvard School of Public Health finds that children and young adults who start...