Biological Explanations for Antidepressant Withdrawal

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Two South African researchers review scientific understanding of the brain changes that lead to antidepressant discontinuation syndrome (ADS) in Human Psycho-pharmacology: Clinical and Experimental....

Antipsychotics Again Strongly Linked to Falls and Fractures

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Three independent studies in two journals reported strong links between antipsychotics and falls and fractures.

Differentiation of SSRI and Benzo Dependence/Withdrawal “Not Rational”

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Researchers from the Cochrane Center and University of Copenhagen in Denmark, publishing in the May issue of Addiction, "explore the rationale for claiming that...

Thoughtful Insight, Not Lack of It, Drives Some Patients to Quit Psychiatric Medications

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Rather than a "lack of insight," it is actually a thoughtful weighing of complex risks and benefits that ultimately drives some people diagnosed with bipolar disorder to eschew psychiatric medications, according to a qualitative study in the Journal of Affective Disorders. And these people often develop sophisticated strategies in their efforts to manage without medications.

New Form of Mice Experiment Reveals Antidepressant’s Dangers Earlier

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Scientists from the University of Utah say they have discovered a new way of doing mice experiments that more sensitively and quickly reveals negative...

ADHD Medication Slows Growth, Increases Obesity

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Treating attention deficit/hyperactivity disorder (ADHD) with stimulants affects growth and is likely to cause a higher BMI in later adolescence, according to research from...

Lilly Faces First Week of “Bellwether” Cymbalta Withdrawal Lawsuit

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Calling it “Poison,” plaintiff Claudia Herrera testified she would not have taken Eli Lilly's drug Cymbalta had she known the risks. Lilly hid the risks of...

FDA-approved Ads Misinform Patients About Antipsychotics and Motor Dysfunction

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Food and Drug Administration-approved information and public advertisements are misleading the public about the actual neurodegenerative risks from second-generation antipsychotics.

Health Canada Adds Suicide Warning to ADHD Medications

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Stronger warnings on the risk of suicidal thoughts and behaviors are being incorporated into the prescribing information for ADHD drugs in Canada.

British Medical Association Takes On Prescription Drug Dependence

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Last year the British Medical Association (BMA) released a report on dependence and withdrawal from prescription drugs including benzodiazepines, z-drugs, opioids, and antidepressants. Now,...

Antipsychotics During Pregnancy Linked to Infant Problems

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“Live, healthy babies are the most common outcome following the use of antipsychotic medication in pregnancy,” conclude Australian researchers in a study that was...

“Serious Breakdown” on Cymbalta Withdrawal Warnings

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"The last four years have seen a 90% increase in the number of serious adverse drug reports received by the Food and Drug Administration," according to a report by the Institute for Safe Medication Practices." Among them, a "signal" that Cymbalta causes "an array of problems such as crying, suicidal ideation, and anger, and other symptoms including effects on appetite and weight gain."

Benzos Fail to Prevent, May Increase PTSD

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In a review of the evidence regarding benzodiazepines, researchers from the University of Michigan find that benzodiazepines used in the treatment of PTSD are...

Prenatal Exposure to SSRIs Significantly Increases Autism & Developmental Delays

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Research on 966 mother-child pairs from the Childhood Autism Risks from Genetics and the Environment (CHARGE) Study finds that prenatal SSRI exposure was nearly 3...

Children on Antipsychotics 50% More Likely to Develop Diabetes

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Antipsychotic drugs increased the risk of children developing diabetes by 50%, and with an antidepressant added, their risk doubled.

2X Risk of Postpartum Hemorrhage Antidepressants

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A study of 106,000 pregnant women with a diagnosis of mood or anxiety disorder, by researchers from Harvard, Duke, Michigan State and the university...

Opioid Use in Pregnancy Dangerous and Understudied

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Nora Volkow, the director of the National Institute on Drug Abuse (NIDA), authored an editorial for BMJ this month warning that the opioid abuse epidemic could have dangerous consequences for pregnant women. While the effects of opioid exposure on the developing brain are yet unknown, research suggests that infants may suffer from withdrawal syndrome, nervous system defects, and impaired attachment with the mother.

Recovery by Taking Psychiatric Drugs versus Recovery by Coming Off of Psychiatric Drugs

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German author and activist Peter Lehmann presents "Recovery by Taking Psychiatric Drugs versus Recovery by Coming Off of Psychiatric Drugs" at the 2012 International Society for Ethical Psychology and Psychiatry (ISEPP) Conference in Philadelphia, PA.

Evidence Lacking for Antidepressant Safety in Nursing Mothers

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A scientific review says we need to know much more about the risks of nursing mothers taking SSRIs.

Autism Linked to Antidepressants During Pregancy

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A study of the Swedish medical birth registry, conducted by researchers from Sweden, the U.K., and the U.S.A., found a 3.3X greater risk of...

Doctors Rarely Warn about Benzo Withdrawal

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The Boston Globe interviews people who became ever more severely dependent on sedating benzodiazepines without realizing it, because as they tried to stop taking...

Elderly With Dementia can be Withdrawn From Antipsychotics

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The Cochrane Library reports that "many older people with Alzheimer's dementia and NPS (neuropsychiatric symptoms) can be withdrawn from chronic antipsychotic medication without detrimental effects...

Pfizer Accused of Knowing Zoloft Antidepressant Caused Birth Defects

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The first of more than 1,000 lawsuits about Zoloft and birth defects has gotten underway.

Psychotropics During Pregnancy Raise Risk of Babies with Low Birth Weight, Hospitalizations

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The use by mothers of any of four major classes of psychiatric medications during pregnancy significantly raises the risk that their babies will be born with low birth weights and will need to be hospitalized.

Withdrawal studies up to 9/23/2005

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M.W. Agelink, A Zitselsberger, E. Kleiser, Withdrawal symptoms after discontinuation of Venlafaxine (letter), Am. J. Psychiatry, 154, 10, October 1997, 1473-1474. G.W. Amsden, F. Georgian,...