Closeup of pills in hand, a magnifying glass

Psychiatric Drugs “A Crude Form of Chemical Restraint”

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Mental health nursing has a key role to play in helping people discontinue the drugs, writes Timothy Wand.

Psychotherapy Can Prevent Relapse When Discontinuing Antidepressants

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“Short and simple psychological programs can prevent people from relapsing when they stop their antidepressants.”

“Relapse” in Antidepressant Trials Likely Caused by Sudden Withdrawal

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A new study investigates how antidepressant withdrawal effects often get confounded with depression relapse in clinical trials.

Many Service Users Interested in Decreasing Antipsychotic Use with Professional Help

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New research examines service user attitudes on discontinuing and reducing antipsychotic drugs.
Doctor welcoming a patient

How Providers Can Support Psychiatric Drug Discontinuation

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Supportive patient-practitioner relationships are crucial to the successful discontinuation of psychiatric medication.

New Study Examines Successful Discontinuation of Antipsychotics

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A new study to be published in the next issue of Schizophrenia Research examines patients suffering from a first-episode of psychosis who stop taking any antipsychotic drugs. The researchers attempt to identify variables that can serve as predictors of the successful discontinuation of antipsychotics. They find, for example, that those who discontinue the drugs have, on average, the same outcomes as those who stay on them, and that those who have better social integration are more likely to discontinue without relapse.

Social Support Improves Antipsychotic Discontinuation, Study Finds

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A new study explores how people manage to discontinue antipsychotic medication and examines how social supports may improve outcomes.

The Ethics of Antipsychotic Dose Reduction and Patient Rights

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New research highlights the ethical responsibilities of clinicians in supporting patients who choose to reduce or discontinue antipsychotic medication.

Antidepressants Linked to Doubling of Failure of Dental Implants

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People who take SSRI antidepressants are twice as likely to have their dental implants fail, according to McGill University researchers. In a press release,...

Smoking Cessation and Psychiatric Drugs Cause the Most Suicidal and Homicidal Reactions

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The popular smoking cessation drug Chantix is the medication that most frequently makes people feel suicidal or homicidal, according to figures gathered by the...

Different Antipsychotics Have Different Effects on Brain Volume

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First generation antipsychotics seem to cause general brain volume loss, while second generation antipsychotics seem to both increase and decrease the thickness of different parts of the brain.

More Evidence Antidepressants Might Induce Sexual Dysfunction Even After Stopping Them

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A retrospective study in the Journal of Clinical Psychiatry examined cases of people who suffered sexual dysfunction that endured even after stopping taking SSRI antidepressants.
Illustration of person with hand to their head, which is dissolving into squares

Post-Acute Withdrawal Syndrome (PAWS): Why Don’t We Know More About It?

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Persistent antidepressant withdrawal is a debilitating experience, but little research exists about its prevalence and treatment.

Autism, Antidepressants, and Pregnancy: The Basics

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This month, the seventh study and eighth study came out on the topic of antidepressant exposure during pregnancy and autism.  And these studies showed, as essentially all of the others have, that antidepressant use during pregnancy (principally with selective serotonin reuptake inhibitors or SSRIs) is associated with autism in the exposed children. With so many children being diagnosed with autism and so many women taking antidepressants during pregnancy, everyone wants to know: are these things (the antidepressants) associated with autism or not?  Quite frankly no one has the time to read through all eight scientific papers (and dozens more animal and basic science studies) to understand this important area, so I will do my best to briefly summarize it here.

Psychiatric Medication Use Associated with Triple the Risk of Stroke

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Common psychiatric medications double the risk of heart attack and triple the risk of stroke, according to research presented at the Canadian Cardiovascular Congress...

Semen Abnormalities Associated with SSRI Antidepressants

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The French non-profit organization Prescrire has produced a special report about the impacts of SSRI antidepressants on male fertility.

African American and Hispanic Youth Discontinue ADHD Treatment at Higher Rates than White Youth

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Study examines racial and ethnic disparities in the quality of care for Medicaid-enrolled children starting ADHD medication.

Major Risks from Drug Interactions in Common Psychiatric Polypharmacy

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It is very common for psychiatric patients, especially those diagnosed with schizophrenia, to be prescribed two or more psychiatric medications at once, and this...

Over One Thousand Boys Grew Breasts “Probably” Caused By Common Psychiatric Medication

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According to an ex-chief of the FDA, Johnson & Johnson knew long before it started warning people that Risperdal could cause boys to grow breasts.

Neuroleptic Drugs and Violence

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Neuroleptic Drugs and Violence by Catherine Clarke SRN, SCM, MSSCH, MBChA. and Jan Evans MCSP. Grad Dip Phys.

Waking Blackouts On Sleep Drugs Can Lead to Dangerous Mishaps

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In her blog on USC Annenberg's Reporting on Health, journalist Martha Rosenberg reviews some of the quantitative evidence and qualitatively bizarre anecdotal evidence of...

Eli Lilly Defeats “Bellwether” Cymbalta Withdrawal Lawsuit

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The Federal jury hearing the first of 5000 claims against Eli Lilly for hiding the risks of withdrawal symptoms associated with Cymbalta found that Lilly did not...

Cognitive Function Improved by Reducing Antipsychotics

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A 28-week randomized controlled study by researchers in Japan, Canada and the United States finds that a 50% reduction of risperidone or olanzapine significantly...

Alarming Report on Antidepressant Side Effects

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Drawing on analysis of data from websites such as Paxilprogress.org, ehealthforum.com, depression forums.org, about.com, medhelp.org, drugLib.com, topic.com and survivingantidepressants.org, researchers from the University of...

Pfizer Sued Over Zoloft’s Failure to Beat Placebo

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A lawsuit filed Wednesday in San Jose, California seeks federal approval for two class-action lawsuits representing all U.S. users of the antidepressant Zoloft, accusing...