Wednesday, December 6, 2023

Schizophrenia and Psychosis

Adderall Use Associated with Increased Risk of Psychosis

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Twice as many teenagers with ADHD experienced severe psychosis when taking Adderall, as compared to Ritalin, according to a new study.

Study Deems Support, Not Drugs, Best for Youth at Risk of Psychosis

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Research by five U.K. universities across multiple sites for up to two years divided 288 young adults (14-35 years) deemed at risk for psychosis...

The Role of Context, Language, and Meaning in Hearing Voices

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Sociocultural context, language, and sense-making process are among concepts that can help hearers and providers better understand the phenomenon of hearing voices

Recovery Is Resiliency

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Recovery is not a bridge we cross and never return to. Rather, it is more like crossing a stream we ford by side-stepping on different stones. Not all of the stones are as sturdy as some of the others. Yes, we slip at times, only to regain our footing and forge ahead.

Long-Term Social Supports Needed After Onset of Psychosis

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New data on the effects of social support after early onset of psychosis suggests that patients with intense social support function better than those without such help, but than once supports are removed the effects diminish.

Researchers Question Add-On Treatment for ‘Schizophrenia’

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A common practice when antipsychotics are found to be ineffective for schizophrenia is to prescribe a second, additional psychoactive medication. Now, a new study suggests that this practice is not supported by the research.

No Treatments Have “Clinically Meaningful” Impacts On Negative Symptoms of Schizophrenia

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While most treatments have had "statistically significant" success in clinical trials, no common psychiatric or psychological treatments improve the negative symptoms of schizophrenia at levels that are "clinically meaningful."
definition of relapse

What Does ‘Relapse’ Mean? Definitions Used in Antipsychotic Trials Are Unclear

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Antipsychotic drugs are prescribed on the basis of trials that demonstrate a higher rate of ‘relapse’ in people who are withdrawn from these drugs compared to those who continue to take them. Yet, incredibly, there is no consensus about what ‘relapse’ means in this situation.

Omega-3 Screening for Psychiatric Symptoms?

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There is a substantial body of evidence suggesting that not getting enough omega-3 fatty acids in your diet may be connected to a diverse array of psychiatric symptoms. In a new study published this month, psychiatrist Robert McNamara and Erik Messamore provide an overview of the evidence and call for screening of omega-3 deficiency in people experiencing symptoms associated with ADHD, depression, mood disorders, and psychosis.

Study Finds First-Episode Psychosis Patients Fare Better with Vitamin D

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Researchers examine the relationship between vitamin D and clinical and cognitive symptoms in first-episode psychosis.

Individuals with Psychosis Symptoms More Likely to be Victimized

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Individuals diagnosed with a psychotic disorder are 4-6 times more likely than the general population to experience victimization.

Researchers Call for Reappraisal of Adverse Mental Effects of Antipsychotics, NIDS

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In a study published yesterday, researchers from the Nippon Medical School in Tokyo bring attention to a condition known as neuroleptic-induced deficit syndrome (NIDS)...

Epilepsy Drugs Can Induce Psychosis in Some Patients, Study Finds

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In this month’s issue of the journal Brain a new study investigates whether the drugs prescribed to control seizures can increase the risk of...

The Dopamine Hypothesis of Schizophrenia – Version III

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The Division of Clinical Psychology of the British Psychological Society published a paper titled Understanding Psychosis and SchizophreniaThe central theme of the paper is that the condition known as psychosis is better understood as a response to adverse life events rather than as a symptom of neurological pathology. The paper was wide-ranging and insightful and, predictably, drew support from most of us on this side of the issue and criticism from psychiatry.  Section 12 of the paper is headed "Medication" and under the subheading "Key Points" you'll find this quote: "[Antipsychotic] drugs appear to have a general rather than a specific effect: there is little evidence that they are correcting an underlying biochemical abnormality."

Researchers Make the Case to Rename Schizophrenia

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The authors outline reasons for renaming schizophrenia and the way a change can reform practice.

Half of Government-Insured Colorado Children Prescribed Antipsychotics are not Psychotic

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According to a report prepared by Colorado University and released to the Denver Post, half of the children on government insurance in Colorado who...

Childhood Victimization Connected with Experiences of Psychosis

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Childhood victimization associated with experiences of psychosis later in life, and in persons without childhood victimization, there is a bidirectional association between psychosis and adult victimization.

Researchers Suggest Traumatic Experiences May Cause Psychotic Symptoms

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A new study in JAMA Psychiatry investigates the relationship between trauma and psychotic experiences.

Study Shows Success With Reduced Antipsychotic Use

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People who reduced antipsychotic use by tapering were doing just as well after five years as those who continued using the drugs.

CAFÉ Study: Real Science or Marketing Exercise?

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I received the following question from a reader regarding the controversial CAFÉ – Comparisons of Atypicals in First Episode of Psychosis - study. (This was the study in which Dan Markingson committed suicide.) "It appears that there was no head-to-head with a control group taking a placebo pill. Nor was there a control group featuring 'old' types of 'antipsychotic'. If that was the case then it is very poor study . . . what on earth can you hope to show from the data?" I started to write a response, but the subject is complex, and my response became the following article.

Cannabis May Precipitate Psychosis

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In a study of 785 patients with a psychotic disorder, researchers from The Netherlands found that cannabis us was associated with an earlier onset...

Review Questions Long Term Use of Antipsychotics

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Patients who recover from a single episode of psychosis are often prescribed antipsychotics long-term, despite a lack of evidence for this practice

Large German Anti-Stigma Campaign Shows Little Effect on Attitudes

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“Overall, this study showed that the information and awareness campaign had almost no significant effects on the general public's attitudes toward people affected by either schizophrenia or depression,” the researchers, led by German medical sociologist Anna Makowski, wrote. “One could assume that deeply rooted convictions cannot be modified by rather time-limited and general activities targeted at the public.”

Of FEP’s, DUP’s and BS

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First episode psychosis (FEP) and duration of untreated psychosis (DUP) remain the foci of great numbers of early intervention programs in Western countries. “Untreated” in DUP-anese is synonymous with unmedicated, which often creates a sense of urgency and a myopic fixation on getting these youth started on anti-psychotics and keeping them on. What is the impact of this medical model and its accompanying chemical imbalance narrative on these emerging adults? How often does it set them on a course of regained functioning and restored hope, or does it serve as a gateway into a lifetime of disability and discouragement?

Psychiatrist Describes Role in Open Dialogue Model of Care

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Psychiatrist outlines varying roles in Open Dialogue model, fostering service-user and family agency through meaningful conversations with a team of providers.