Schizophrenia and Psychosis

Outcome Reporting Bias in Antipsychotic Medication Trials

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A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.

Antipsychotic Use Does Not Correlate With Conversion to Psychosis

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Researchers in Brazil find, in a meta-analysis, that only 30% of youth deemed to be of ultra high risk of psychosis do in fact...

Researchers Test Harms and Benefits of Long Term Antipsychotic Use

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Researchers from the City College of New York and Columbia University published a study this month testing the hypothesis that people diagnosed with schizophrenia treated long-term with antipsychotic drugs have worse outcomes than patients with no exposure to these drugs. They concluded that there is not a sufficient evidence base for the standard practice of long-term use of antipsychotic medications.

“Diagnostic Dissent”: Experiences of Individuals Who Disagreed With Their Diagnosis

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Researchers investigate the first-person experiences of people who disagreed with their psychiatric diagnosis of psychosis.

Study Explores Cognitive Effects of Antipsychotics

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Reduced usage of antipsychotics in first-episode psychosis was associated with improved executive functioning.

Have You Ever Taken an Experimental Antipsychotic Called Bifeprunox?

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In 2004, a patient was given an experimental antipsychotic called bifeprunox and died of hepatorenal failure nine days later. But the sponsor apparently did not investigate the death for three years. In late 2007 the sponsor issued a safety alert and suspended all bifeprunox studies. This is where things get interesting.

Psych Patients Who Resist Stigma Do Better

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A new study in press in the Journal of Schizophrenia Research finds that patients who actively resist the negative stigma associated with mental health...

Fact-Checking the General Counsel in the Markingson Case

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Ever since critics began asking questions about the death of Dan Markinson in a clinical trial at the University of Minnesota, the General Counsel for the university, Mark Rotenberg, has responded with a uniform message: the case has already been investigated many times, and no wrongdoing has ever been found. That's how Rotenberg responded to my article about the case in Mother Jones, and that's how he responded last week to the news that the Board of Social Work had issued a “corrective action” to the study coordinator for the clinical trial in which Markingson died.

J&J Loses $1.75 Million in Risperdal Male Breast Trial; Thousands of Cases Pending

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In the third major verdict of its kind, drug giant Johnson & Johnson was ordered to pay a Maryland man who grew female breasts while taking the antipsychotic Risperdal. The company failed to warn doctors, patients, and regulators of the risk of abnormal breast development in young males and now faces about 5,400 lawsuits involving the drug.

Social Recovery Therapy for First Episode Psychosis

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Social Recovery Therapy shows promising results for individuals who experience first-episode psychosis.

The Role of Context, Language, and Meaning in Hearing Voices

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Sociocultural context, language, and sense-making process are among concepts that can help hearers and providers better understand the phenomenon of hearing voices

As Lawyers and Bureaucrats Delay, The Body Count Rises

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It took over twenty years for the state medical board to sanction a Minnesota psychiatrist who was responsible for the deaths and injuries of 46 patients. Today, in the Markingson case, it looks as if history is repeating itself. How many patients die while bureaucrats delay?

Study Suggests Long-Term Antipsychotic Use May Result in Poorer Cognitive Functioning

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Association found between long-term antipsychotic use and poorer performance on cognitive tasks in adults diagnosed with ‘schizophrenia.’

Adderall Use Associated with Increased Risk of Psychosis

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Twice as many teenagers with ADHD experienced severe psychosis when taking Adderall, as compared to Ritalin, according to a new study.
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A Faux Test for a Faux Disease Promoted by Real Psychiatrists

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Influential psychiatrists recently called on the NHS to make a faux schizophrenia test available to patients and their families. What is most astounding about this is the complete lack of pretense. "We are so certain of our power and righteousness that we are going to tell you to your face that we are lying, and yet, we will still get our way."

In Patients Diagnosed with Schizophrenia, Depression Linked to More Accurate Assessments

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Participants diagnosed with schizophrenia with higher levels of self-reported depression have more accurate assessments of abilities.

20-Year Data Show Antipsychotics Do Not Reduce Psychosis

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Martin Harrow's study tracing the effects of antipsychotics on 139 schizophrenia (SZ) and mood-disordered patients over 20 years, just published in Psychological Medicine, finds...

Children with ‘ADHD’ Commonly Prescribed Antipsychotics

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Despite little evidence for benefit, and substantial risk of harm, antipsychotics are commonly prescribed to children diagnosed with ADHD

Exercise Effective for Early Psychosis, Studies Show

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A new study out of the University of Manchester found that personalized exercise programs reduced the symptoms for young people suffering from their first episode of psychosis. Researchers also conducted an accompanying qualitative analysis and found that the participants experienced improved mental health, confidence, and a sense of achievement and felt that autonomy and social support were critical to their success.

From Self Care to Collective Caring

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As a trauma survivor growing up in various adolescent mental health systems, I never learned any useful self-care tools or practices. I was taught that my current coping skills (self-injury, suicidal behavior, illicit drug use) were unacceptable, but not given any ideas as to what to replace them with. No one seemed to want to know much about the early childhood traumas that were driving these behaviors. Instead, I collected an assortment of diagnoses. I was told that I would be forever dependent on mediated relationships with professionals, and an ever-changing combination of pills. The message was that my troubles were chemical in nature and largely beyond my control.

Parachute NYC Peer Support Program Presents Challenges and Opportunities

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Anthropologists study Parachute NYC to identify challenges and opportunities for implementing peer support and Open Dialogue practices.

Increased Risk of Movement Disorders From Antipsychotics in Persons with Intellectual Disabilities

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Large cohort study demonstrates that those with an intellectual disability are at an increased risk for movement disorder side effects of antipsychotics.

Study Connects Environmental Risk Factors and Psychosis

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A meta-analysis of known risk factors for psychosis finds elevated risk with the presence of childhood trauma, adverse life events, and affective dysfunction.

Childhood Victimization Connected with Experiences of Psychosis

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Childhood victimization associated with experiences of psychosis later in life, and in persons without childhood victimization, there is a bidirectional association between psychosis and adult victimization.

Minority Discrimination Linked to Psychosis

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A study published in this month’s issue of the Social Psychiatry and Psychiatric Epidemiology found that perceived discrimination related to minority status may precede...