No Benefit for Adding Antidepressants to CBT in Severe Depression

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For those with severe depression, inpatient CBT was effective but the adding antidepressants did not improve treatment outcomes.

Adverse Reactions to Psychiatric Medications Hospitalize 17,000 Annually

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Nearly 90,000 American adults are going to emergency rooms every year in response to adverse events from psychiatric medications, according to a study in...

Antidepressants & Sexual Function

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Two studies of the effects of antidepressants on sexual function - one on the relative effects across classes of antidepressants on men, the other...

JAMA Psychiatry Retracts Antidepressant Study

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Once an appropriate statistical method was used, the study findings were “no longer valid,” according to the editors of JAMA and JAMA Psychiatry.

Prescription Drugs May Cause One Third of All Birth Defects

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Up to a third of all birth defects may be linked to prescription drugs, according to a review of the evidence published in The...

Antidepressants and Diabetes Risk

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A meta-analysis by researchers from the U.K. finds an association between antidepressant use and a modestly increased risk of diabetes. “Our research shows that...

Antidepressants Increase Risk of Death in ICU

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An analysis of electronic records from admissions to four ICU's in 2001-2008 showed that the 1,876 patients who were on an SSRI or SNRI...

Internet Data Mining Reveals Unreported Side Effect

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Scientists at Microsoft, Stanford and Columbia University, using automated software to mine data from 82 million internet searches for information related to, found a...

New Zealand Asks: “How is Your Antidepressant Working For You?”

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Researchers at Auckland University have launched a study that "positions the people who are prescribed antidepressants as the experts" and which aims at asking...

Antidepressant Use Associated with Brain Atrophy and Lesions in Elderly

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In a study of 630 elderly Manhattanites without dementia, researchers from the Netherlands found that antidepressant use was associated with significantly more brain atrophy,...

Quality of Relationship to Doctor Significantly Improves Antidepressant Efficacy

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The more that patients feel that they have a high-quality relationship with their prescribing physician, the more likely that they will regard their own responses to antidepressants as positive.

Evidence Lacking for Antidepressant Safety in Nursing Mothers

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A scientific review says we need to know much more about the risks of nursing mothers taking SSRIs.

Researchers Investigate Antidepressant-Induced Suicidal Ideation

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An increase in suicidal thoughts is a known and serious side-effect for various types of antidepressants. Recent studies suggest that there may be some...

Fish Exposed to Prozac Exhibit Significantly Altered Behavior

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Concentrations of Prozac as low as 1 microgram per liter (μg/L), a concentration that has been found in many freshwater environments, were found to significantly...

Antidepressants, Not Depression, Raise Risk of Preeclampsia in Pregnancy

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In a study of 69,448 pregnant women with depression, researchers from the Harvard school of public health found that use of SSRI (selective serotonin...

Psychotropics During Pregnancy Raise Risk of Babies with Low Birth Weight, Hospitalizations

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The use by mothers of any of four major classes of psychiatric medications during pregnancy significantly raises the risk that their babies will be born with low birth weights and will need to be hospitalized.

Autism Linked to Antidepressants During Pregancy

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A study of the Swedish medical birth registry, conducted by researchers from Sweden, the U.K., and the U.S.A., found a 3.3X greater risk of...

Risk of Bone Fractures With SSRIs Greater Than Thought

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Researchers from McMaster University's Department of Medicine, presenting at this year's American Society for Bone and Mineral Research's annual meeting, found that the magnitude...

Increased Risk of Heart Defects with SSRIs

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Danish research found a significantly increased risk of congenital heart defects in both the 4,183 pregnancies exposed to SSRIs throughout the first trimester and the...

Antidepressant is Toxic to Fungus

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Zoloft isn't just for depression any more; it also kills fungal meningitis. Researchers from Texas A&M find that "The problem for many current antifungal...

Psych Med Prescribing After Perinatal/Neonatal Death

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Research from MIA blogger Jeffrey Lacasse finds that "at present, there exists no rigorous evidence to support the prescription of Ads (antidepressants) in bereavement....

Antidepressants Cause Autism-Like Gene Expression in Fish

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Prozac, Effexor, and/or carbamazepine induce gene expression patterns in the brains of fathead minnows that mimic those thought to be associated with autism in...

SSRIs: More Harm Than Good

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Beginning with an "evolutionary analysis" and a review of serotonin's role in the body, researchers from Canada and the U.S. conduct a thorough review...

Fluoxetine in Adolescence Raises Sensitivity to Stress in Adults

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Research on neurochemicals associated with moods in mice and rats finds that, while less depression-like behavior was observed in those receiving fluoxetine (Prozac) administration...

SSRIs Increase Post-Surgical Complications

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A study of 530,000 patients who underwent surgery at 375 U.S. hospitals found a 10% increased risk of post-operative complications including bleeding, transfusion, hospital...