Researchers Warn of “Brain Atrophy” in Children Prescribed Antipsychotics

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Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.

2nd-Generation Antipsychotics Cause Extrapyramidal Side Effects as Much as 1st-Generation

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According to researchers from Yale and the U.K., the improvements in extrapyramidal side effects expected from 2nd-generation antipsychotics has not been realized, while the...

Baseline Lipid Monitoring with Antipsychotics “Disappointingly Low”

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"Even in an academic setting with active discussions among psychiatrists regarding issues of metabolic risk ... baseline lipid monitoring is disappointingly low" according to...

Alberta Long-term Care Homes Reduce Antipsychotic Use by 50%

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The provincial government health service of Alberta, Canada recently concluded a successful pilot project that reduced the use of antipsychotic medications for patients with...

Antipsychotics for Poor Kids Soar, Mostly for Behavior Problems

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Cross-sectional analysis by the University of Maryland and Johns Hopkins University of 456,315 youths enrolled in Medicaid between 1997 and 2006 finds that the...

Antipsychotics Change the Architecture of the Colon

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Researchers in Singapore find that antipsychotic medications are associated with changes to colonic architecture, which could result in difficult colonoscopy and increased colonoscopy-related risks....

Researchers Call for Reappraisal of Adverse Mental Effects of Antipsychotics, NIDS

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In a study published yesterday, researchers from the Nippon Medical School in Tokyo bring attention to a condition known as neuroleptic-induced deficit syndrome (NIDS)...

Review Questions Long Term Use of Antipsychotics

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Patients who recover from a single episode of psychosis are often prescribed antipsychotics long-term, despite a lack of evidence for this practice

Half of First-Episode Patients Respond to Antipsychotics

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No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.

Researchers Struggle as Placebos Becoming More Effective & Antipsychotics Losing Power

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Since the 1960s, the positive response rates to antipsychotic medications have been dropping steadily, according to a meta-analysis published in JAMA Psychiatry by Columbia...

20-Year Data Show Antipsychotics Do Not Reduce Psychosis

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Martin Harrow's study tracing the effects of antipsychotics on 139 schizophrenia (SZ) and mood-disordered patients over 20 years, just published in Psychological Medicine, finds...

Children on Antipsychotics 50% More Likely to Develop Diabetes

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Antipsychotic drugs increased the risk of children developing diabetes by 50%, and with an antidepressant added, their risk doubled.

Off-Label Antipsychotic Use Among Children Soaring

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Researchers from Philadelphia and Baltimore find, in a study of Medicaid records for 50 states and the District of Columbia, that antipsychotic prescribing to...

More Evidence That Antipsychotics Shrink the Brain

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European researchers who reviewed 43 imaging studies of first-episode psychosis found evidence that antipsychotics cause a decrease in gray matter volumes in the brain....

New Rating Tool for Tapering Antidepressants and Antipsychotics

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Researchers developed a rating scale to better assess service users’ experiences tapering antidepressant and/or antipsychotic medication.

Reducing Antipsychotic Use May Improve Health for People with Mental Health Diagnoses

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A new study offers radical solutions for improving the cardiovascular health of people with mental health diagnoses: reducing antipsychotic prescriptions..

Schizophrenia Prevents Cancer; Antipsychotics May Cause It

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In a review of all 59,233 individuals diagnosed with schizophrenia in Sweden between 1965 and 2008, researchers from Sweden and the U.S. identified 6137...

Osteoporosis Associated with Antipsychotic Treatment

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Chinese researchers find, in a literature review for the International Journal of Endocrinology find an increased rate of osteoporosis among people with a schizophrenia...

Second-Generation Antipsychotics Just as Likely as Older Drugs to Cause EPS

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In a study of an earlier randomized controlled trial of antipsychotics, researchers from Yale and the U.K found that second-generation antipsychotics were as likely...

Researchers Challenge Industry-Friendly Depression Guideline

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Review of a new mixed depression guideline reveals financial bias of guideline developers and lack of evidence supporting recommendations for prescribing of antipsychotics.

Two-Thirds of Schizophrenia Patients Do Not Remit on Antipsychotics

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A new analysis of antipsychotic treatment of schizophrenia (published in Schizophrenia Bulletin) has found that two-thirds of patients treated this way do not experience symptom remission.