New Study Casts Doubt on Efficacy of Ketamine for Depression

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A new study, published this month in the Journal of Affective Disorders, investigated the effectiveness of weekly intravenous ketamine injections as a treatment for...

Researchers Expose Pharmaceutical Industry Misconduct and Corruption

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Corruption of pharmaceutical industry sponsored clinical trials identified as a “major obstacle” facing evidence-based medicine.

Long-term Usage of ADHD Drugs Linked to Growth Suppression

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Findings suggest that treatment not only fails to reduce the severity of “ADHD” symptoms in adulthood but is associated with decreased height.

The “Shotgun Method” – A Story of Mental Health Crisis in Iceland

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"Let's try the shotgun method," my psychiatrist said — meaning that you load the gun with a bunch of pellets and hope that one of them hits the target. I went through 16 different psychiatric medications in five years, and they were not the right choice for me.

Feral Psychiatry: The Case of Garth Daniels

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Garth Daniels, a 39-year-old Melbourne man, has been shackled for 110 days and forced to undergo ECT 94 times at three times a week against his will. Last year, his family asked me to provide a second opinion on Garth’s case. As predicted, my recommendations against continued ECT were quickly dismissed by the hospital. There are critically important issues at stake in this case.

Researchers: Antidepressant Withdrawal, Not “Discontinuation Syndrome”

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Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.

Children with ‘ADHD’ Commonly Prescribed Antipsychotics

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Despite little evidence for benefit, and substantial risk of harm, antipsychotics are commonly prescribed to children diagnosed with ADHD

Prominent Researcher and Psychotherapist Questions “Evidence-Based Therapy”

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Dr. Johnathan Shedler recently published a paper critiquing how the term “evidence-based” is being used in the field of psychotherapy.

Violence Caused by Antidepressants: An Update after Munich  

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The media is now reporting details about the 18-year-old who shot and killed nine and wounded many others before killing himself on July 22 in Munich. My clinical and forensic experience leads to a distinction among people who murder under the influence of psychiatric drugs. Those who kill only one or two people, or close family members, often have little or no history of mental disturbance and violent tendencies. The drug itself seems like the sole cause of the violent outburst. On the other hand, most of those who commit mass violence while taking psychiatric drugs often have a long history of mental disturbance and sometimes violence. For these people, the mental health system seems to have provoked increasing violence without recognizing the danger.

Researchers Warn of “Brain Atrophy” in Children Prescribed Antipsychotics

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Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.

Hallucinations Reported as Side Effect of ADHD Medication

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Hallucinations and other psychotic symptoms have been reported after methylphenidate (Ritalin) treatment for ADHD.

Safety Analysis Weighs Harms and Benefits of Antipsychotic Drugs

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The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.

Antidepressants Increase Risk of Death, Study Finds

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Antidepressants are commonly considered safe and effective treatments. However, research has questioned their efficacy, and now, their safety.

Philosophers Challenge Psychiatry and its Search for Mechanisms of Disorder

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Attempting to locate the mechanisms of psychiatric disorder is a step in the wrong direction and fails to challenge potentially unjust social practices.
risk versus reward

Randomized Controlled Trials of Psychiatric Drugs Tell of Harm Done

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The most important data in an RCT is not whether the drug provides a statistically significant benefit over placebo. The most important data is the “number needed to treat” calculation (NNT). For the person considering taking an antidepressant or an antipsychotic, the NNT data provides the “math” needed to weigh the potential benefit of taking the drug against the potential harm of doing so.

Treating Metabolic Conditions May Resolve Some Depressive Symptoms

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New research suggests that treatable metabolic abnormalities underlie some treatment-resistant cases of depression—and treating the metabolic condition has the possibility of dramatically reducing depressive symptoms

Epilepsy Drugs Can Induce Psychosis in Some Patients, Study Finds

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In this month’s issue of the journal Brain a new study investigates whether the drugs prescribed to control seizures can increase the risk of...

Antidepressant Use Linked to Longer, More Frequent Psychiatric Rehospitalization

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New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.

Transcranial Magnetic Stimulation No Better Than Placebo for Treatment-Resistant Depression

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A new study in JAMA Psychiatry found that transcranial magnetic stimulation was no better than placebo for treatment-resistant depression.

Scientists Clarify Risks of Augmenting with Antipsychotic Medications for Depression

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The researchers found that while antipsychotic drugs may be slightly more effective than alternative antidepressants, they come with a much higher side effect burden.

Researchers Ask, ‘Why Do Antidepressants Stop Working?’

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An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.

Lancet Psychiatry’s Controversial ADHD Study: Errors, Criticism, and Responses

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Amid calls for a retraction, Lancet Psychiatry publishes articles criticizing the original finding and a response from the authors.

Study Finds Improved Functioning for ‘Schizophrenia’ Without Antipsychotics

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Long-term treatment with antipsychotic drugs is currently considered the standard treatment for patients diagnosed with ‘schizophrenia.’ A new study challenges this practice, however. The...

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

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A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

Study Suggests Long-Term Antipsychotic Use May Result in Poorer Cognitive Functioning

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Association found between long-term antipsychotic use and poorer performance on cognitive tasks in adults diagnosed with ‘schizophrenia.’