Reimagining Healthcare

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The conventional Western classification systems of health conditions are based on flawed science shaped by reductionist, hierarchical, and profit-driven ideologies. THEN wants to create a new paradigm built upon principles drawn from systems science, the life course perspective, developmental neurobiology, and other evidence-informed studies.

Adverse Effects: The Perils of Deep Brain Stimulation for Depression

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Hundreds of people have been given remote control deep brain stimulation implants for psychiatric disorders such as depression, OCD and Tourette’s. Yet DBS specialists still have no clue about its mechanisms of action and research suggests its hefty health and safety risks far outweigh benefits.

Transcranial Magnetic Stimulation No Better Than Placebo for Treatment-Resistant Depression

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A new study in JAMA Psychiatry found that transcranial magnetic stimulation was no better than placebo for treatment-resistant depression.

New Data on the Adverse Effects of Meditation and Mindfulness

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Study reports on the less-examined findings of difficult and painful meditation-related experiences.

Researcher Acknowledges His Mistakes in Understanding Schizophrenia

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Sir Robin Murray, a professor at the Institute of Psychiatry, Psychology, and Neuroscience in London, states that he ignored social factors that contribute to ‘schizophrenia’ for too long. He also reports that he neglected the negative effects antipsychotic medication has on the brain.

Experts Question the Benefits of Brain Imaging Research for OCD

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Two experts—a leading neuroscientist studying OCD, and a psychiatrist specializing in OCD treatment—question whether expensive brain imaging research has added anything to the treatment of OCD.

New Medications Fail to Show Efficacy for Alzheimer’s Disease

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Three phase III clinical trials assessing the efficacy of Lundbeck’s investigational drug idalopirdine for Alzheimer’s disease have failed

No Brain Connectivity Differences Between Autism, ADHD, and “Typical Development”

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Neuroscience researchers find no differences in brain connectivity between children with diagnoses of autism, ADHD, and those with no diagnoses.

Trauma Resiliency Model: A New Somatic Therapy for Treating Trauma

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Report presents new body-based therapeutic approach for shock and complex developmental trauma.

Thoughts on the Meaning of Neuroscience

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For me there are at least four separate questions to be addressed. The first is whether neuroscience is capable of understanding human emotion and higher level cognitive experiences. The second is the extent to which that understanding - even if it is achievable - is critical to our being able to help people in distress. The third is whether is it is correct to assume, as many people seem to do, that if we come to some basic understanding of brain function as it pertains to core human emotion and suffering that this will automatically translate into treatments that are commonly thought of as "biological," such as drug treatment. The fourth relates to the limitations and relevance of studying the brain in isolation when we are constantly in interaction with our environment.

Questioning the Philosophical Assumptions of Neuroscience Research

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Are philosophical misunderstandings behind the failure of neuroscience to provide useful clinical research?

Ioannidis Questions Strength of Psychology and Neuroscience Literature

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Last week, well-known Stanford scientist John Ioannidis and his colleague Denes Szucs released a new analysis online. They examined research published in eighteen prominent...

Brain Scans Cannot Differentiate Between Mental Health Conditions

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A new study analyzing over 21,000 participants found that differences in activation of brain regions in different psychological “disorders” may have been overestimated, and confirms that there is still no brain scan capable of diagnosing a mental health concern.

The Genetics of Schizophrenia: A Left Brain Theory about a Right Brain Deficit in...

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In recent months, two teams of researchers in the UK and the US published complementary findings about the epigenetic origins of schizophrenia that have scientific communities who indulge in ‘genetic conspiracy theories’ abuzz. While these results are intriguing, and no doubt involve pathbreaking research methodologies, this line of thought represents a decontextualized understanding both of the symptoms that are typically associated with schizophrenia, and their causes.

Mental Health Concerns Not “Brain Disorders,” Say Researchers

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The latest issue of the journal Behavioral and Brain Sciences features several prominent researchers arguing that mental health concerns are not “brain disorders.”

Madness and the Family, Part III: Practical Methods for Transforming Troubled Family Systems

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We are profoundly social beings living not as isolated individuals but as integral members of interdependent social systems—our nuclear family system, and the broader social systems of extended family, peers, our community and the broader society. Therefore, psychosis and other forms of human distress often deemed “mental illness” are best seen not so much as something intrinsically “wrong” or “diseased” within the particular individual who is most exhibiting that distress, but rather as systemic problems that are merely being channeled through this individual.

United Nations Report Calls for Revolution in Mental Health Care

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In a new report, the United Nations Special Rapporteur on the right to health, Dr. Dainius Pūras, calls for a move away from the biomedical model and “excessive use of psychotropic medicines.”

Brief Trauma-Focused Psychotherapies Effective for Children with PTSD

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Eye Movement Desensitization and Reprocessing Therapy and Cognitive Behavioral Writing Therapy both reduce PTSD symptoms in children who experienced a single traumatic event.

Non-Medical Treatments for PTSD Effective, Study Suggests

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Group-based MBSR and PCGT therapies effective as a complementary treatment for PTSD.

New Study Raises Doubts About fMRI Neuroimaging Research

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More than forty thousand papers have been published using functional magnetic resonance imaging (fMRI) technology to explore the brain. A new analysis of the common...

Mindfulness Therapy Can Prevent Depression Relapse, Review Finds

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Mindfulness-based cognitive therapy (MBCT) may be more effective at reducing the risk of depressive relapse compared to current standard treatments with antidepressant drugs. A...

Misconceptions About Brain Science Very Common, Study Finds

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Researchers investigate commonly held misconceptions about brain research among Americans.

Mindfulness Pain Relief Distinct from Placebo Effect

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A new study demonstrates that the practice of mindfulness may ease pain in a way that is mechanistically distinct from the placebo effect. Research, published in the Journal of Neuroscience, found that mindfulness meditation not only outperformed placebo and fake meditation for pain relief but that it also activated different brain regions than the placebo treatments.

A Blueprint for an ‘Ecosocial’ Person-Centered Psychiatry

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New article pushes for a shift from a psychiatry centered on brain circuitry toward an 'ecosocial' view of mind, brain, and culture.

Neurosexism: Study Questions Validity of Gender-based Neuroscientific Results

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Neuroscientific results that class humans into two categories, “male” and “female,” tend to reify gender stereotypes by giving them the appearance of objective scientific truth.