Reimagining Healthcare

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The conventional Western classification systems of health conditions are based on flawed science shaped by reductionist, hierarchical, and profit-driven ideologies. THEN wants to create a new paradigm built upon principles drawn from systems science, the life course perspective, developmental neurobiology, and other evidence-informed studies.

Transcranial Magnetic Stimulation No Better Than Placebo for Treatment-Resistant Depression

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A new study in JAMA Psychiatry found that transcranial magnetic stimulation was no better than placebo for treatment-resistant depression.

Adverse Effects: The Perils of Deep Brain Stimulation for Depression

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Hundreds of people have been given remote control deep brain stimulation implants for psychiatric disorders such as depression, OCD and Tourette’s. Yet DBS specialists still have no clue about its mechanisms of action and research suggests its hefty health and safety risks far outweigh benefits.

New Data on the Adverse Effects of Meditation and Mindfulness

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Study reports on the less-examined findings of difficult and painful meditation-related experiences.

Researcher Acknowledges His Mistakes in Understanding Schizophrenia

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Sir Robin Murray, a professor at the Institute of Psychiatry, Psychology, and Neuroscience in London, states that he ignored social factors that contribute to ‘schizophrenia’ for too long. He also reports that he neglected the negative effects antipsychotic medication has on the brain.

No Brain Connectivity Differences Between Autism, ADHD, and “Typical Development”

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Neuroscience researchers find no differences in brain connectivity between children with diagnoses of autism, ADHD, and those with no diagnoses.

Brain Scans Cannot Differentiate Between Mental Health Conditions

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A new study analyzing over 21,000 participants found that differences in activation of brain regions in different psychological “disorders” may have been overestimated, and confirms that there is still no brain scan capable of diagnosing a mental health concern.

Mental Health Concerns Not “Brain Disorders,” Say Researchers

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The latest issue of the journal Behavioral and Brain Sciences features several prominent researchers arguing that mental health concerns are not “brain disorders.”

United Nations Report Calls for Revolution in Mental Health Care

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In a new report, the United Nations Special Rapporteur on the right to health, Dr. Dainius Pūras, calls for a move away from the biomedical model and “excessive use of psychotropic medicines.”

Trauma Resiliency Model: A New Somatic Therapy for Treating Trauma

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Report presents new body-based therapeutic approach for shock and complex developmental trauma.

Ioannidis Questions Strength of Psychology and Neuroscience Literature

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Last week, well-known Stanford scientist John Ioannidis and his colleague Denes Szucs released a new analysis online. They examined research published in eighteen prominent...

Can a Conceptual Competence Curriculum Bring Humility to Psychiatry?

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Training for conceptual competence in psychiatry provides a new way forward to address theoretical and philosophical issues in mental health research and practice.

Meditation and Exercise Reduce Depression Symptoms 40%

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A combination of exercise and meditation done twice a week over two months may reduce depression symptoms by 40 percent, according to a new study published open-access this month in Translational Psychiatry. Following the eight-week intervention, the student participants that had previously been diagnosed with major depressive disorder (MDD) reported significantly less symptoms and ruminative thoughts and students without any such diagnoses also showed remarkable improvements.

Brain Imaging Reveals Psychiatric Disorders are Not Neurological Disorders

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Some researchers have been arguing to reclassify all psychiatric disorders as diseases of the brain and nervous system, similar to epilepsy or Parkinson's disease. Neuroimaging research, however, reveals that psychiatric disorders appear to be distinct from neurological disorders, according to a new study published in this month’s issue of the British Journal of Psychiatry.

The Genetics of Schizophrenia: A Left Brain Theory about a Right Brain Deficit in...

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In recent months, two teams of researchers in the UK and the US published complementary findings about the epigenetic origins of schizophrenia that have scientific communities who indulge in ‘genetic conspiracy theories’ abuzz. While these results are intriguing, and no doubt involve pathbreaking research methodologies, this line of thought represents a decontextualized understanding both of the symptoms that are typically associated with schizophrenia, and their causes.

New Evidence for Brain-Gut Link in Depression and Quality of Life

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The first ever population-level study of the brain-gut connection in humans finds evidence for a link between gut bacteria and mental health.

Madness and the Family, Part III: Practical Methods for Transforming Troubled Family Systems

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We are profoundly social beings living not as isolated individuals but as integral members of interdependent social systems—our nuclear family system, and the broader social systems of extended family, peers, our community and the broader society. Therefore, psychosis and other forms of human distress often deemed “mental illness” are best seen not so much as something intrinsically “wrong” or “diseased” within the particular individual who is most exhibiting that distress, but rather as systemic problems that are merely being channeled through this individual.

German Psychologists Declare “the Drugs Don’t Work”

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Jürgen Margraf and Silvia Schneider, both well-known psychologists at the University of Bochum in Germany, claim that psychotropic drugs are no solution to mental...

Research Shows Mindfulness can Decrease Anxiety

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A new study explores the impact of a Mindfulness-Based intervention on stress-related biomarkers in individuals diagnosed with Generalized Anxiety Disorder (GAD).

Researchers Develop New Model for Understanding Depression

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Acknowledging that current depression treatments are failing many people, researchers from Michigan State and MIT have developed a new model for understanding how multiple psychological, biological, social and environmental factors contribute to depression.

Moral Enhancement Technologies are Reportedly Ineffective, Impractical, and Unwise

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A new paper published in Bioethics assesses proposals to “enhance morality” through neuropharmacological and neurotechnological interventions.

Thoughts on the Meaning of Neuroscience

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For me there are at least four separate questions to be addressed. The first is whether neuroscience is capable of understanding human emotion and higher level cognitive experiences. The second is the extent to which that understanding - even if it is achievable - is critical to our being able to help people in distress. The third is whether is it is correct to assume, as many people seem to do, that if we come to some basic understanding of brain function as it pertains to core human emotion and suffering that this will automatically translate into treatments that are commonly thought of as "biological," such as drug treatment. The fourth relates to the limitations and relevance of studying the brain in isolation when we are constantly in interaction with our environment.

Large Rigorous Study Debunks Popular Gene-Environment Theory of Depression

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A large and rigorous meta-analysis fails to find support for the gene-environment interaction theory of depression.

Neurosexism: Study Questions Validity of Gender-based Neuroscientific Results

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Neuroscientific results that class humans into two categories, “male” and “female,” tend to reify gender stereotypes by giving them the appearance of objective scientific truth.

Mindfulness Pain Relief Distinct from Placebo Effect

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A new study demonstrates that the practice of mindfulness may ease pain in a way that is mechanistically distinct from the placebo effect. Research, published in the Journal of Neuroscience, found that mindfulness meditation not only outperformed placebo and fake meditation for pain relief but that it also activated different brain regions than the placebo treatments.