Medication Tapering/Withdrawal

After long-term use, most people are going to have serious symptoms when stopping SSRIs. Many people are going to have transient, mild to moderate difficulty and some are going to end up falling down the akathisia rabbit hole. That is a long, difficult drop.

In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.

A new study by Peter Groot and Jim van Os has found that tapering strips help people successfully discontinue antidepressant medications.

Nobody told me what it would be like when I first stopped taking antidepressants. The worst is definitely over, but I’m still experiencing some lingering side effects. When the hyper-arousal to sights and sounds kicks in and my head starts buzzing, I’ve learned some ways to cope.

In the first systematic review of withdrawal problems that patients experience when trying to get off SSRI antidepressant medications, researchers found that withdrawing from SSRIs was comparable to trying to quit addictive benzodiazepines.

A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

“What I’d really like to do is stop everything,” I say. The reality is that psychiatrists are not the experts when it comes to getting people off psychiatric drugs.

My doctor insisted that my symptoms could not be associated with withdrawal – they had to be symptoms of an underlying condition. I have since learned from legitimate sources that protracted withdrawal syndrome from benzodiazepines can intensify long before it abates, with some symptoms lasting for years.

My study, in which I slowly withdrew people from prescribed antipsychotics and antidepressants, found that it is possible to decrease both spending on psychiatric drugs and patients' chronic exposure to them. In general, the drug-reduction process was well-tolerated and well-accepted among those treated.

People who reduced antipsychotic use by tapering were doing just as well after five years as those who continued using the drugs.

Confronting existential anxiety through “Basal Exposure Therapy” shows promising results in people withdrawing from psychotropic drugs.

Effects of discontinuing SSRIs and SNRIs reported on an online forum indicate significant and long-lasting withdrawal symptoms.

Medically-induced harm—affecting tens of millions of people worldwide—has taken the field decades to take seriously.

It is hard to believe that a year has gone past since I posted Playing the Odds: Antidepressant Withdrawal and the Problem of Informed Consent. The feedback I received underscored the more controversial aspects of SSRI toxicity.  Common themes concerned the abrupt onset of new symptoms 3 to 12 months after stopping the drug, reinstatement of the drug failing to help withdrawal related symptoms, the possibility that withdrawal-related symptoms can persist indefinitely and concerns about using benzodiazepines to help with tardive akathisia.

When Carina Håkansson sent out an invitation for a symposium on "Pharmaceuticals: Risks and Alternatives," some of the world's top scientists, along with experts-by-experience, came from 13 countries to explore better ways to respond to people in crisis.

A new study to be published in the next issue of Schizophrenia Research examines patients suffering from a first-episode of psychosis who stop taking any antipsychotic drugs. The researchers attempt to identify variables that can serve as predictors of the successful discontinuation of antipsychotics. They find, for example, that those who discontinue the drugs have, on average, the same outcomes as those who stay on them, and that those who have better social integration are more likely to discontinue without relapse.

Here I was, 15 years old and already in a long-term treatment facility. I was, on paper: crazy! This entire time, all the adults in my life had been speaking for me. I never felt like I was any of the things they said, but I went along with it. What else could I have done? Every time I rebelled, it only confirmed to my mother what she thought of me.

The authors conclude that the risk of treatment failure or relapse after discontinuation of antipsychotics does not decrease during the first eight years of illness, and that long-term antipsychotic treatment is associated with increased survival. This is a sobering finding and the paper warrants careful review.

I live a slow paced life. I meditate every morning, refuse to get a smart phone (yet), and it takes me generous amounts of time to do things. This isn't because I am “stupid” or slow to get things. Sometimes I wonder how others get so much done each day - yet the quality and vibration of what I do is unique. It needs time. How does this relate with psychiatric drugs? Psych drugs are rooted in impatience, urgency, emergency.

Revealing the false information provided about psychiatry should cause any thinking person, patient, thought-leader or politician to wonder: “how many otherwise normal or potentially curable people over the last half century of psych drug propaganda have actually been mis-labeled as mentally ill (and then mis-treated) and sent down the convoluted path of therapeutic misadventures – heading toward oblivion?”

I was a psychiatrist who participated in the Recovery After an Initial Schizophrenia Episode Early Treatment Program (RAISE ETP). Although I welcomed the positive headlines that heralded the study's results, the reports left me with mixed feelings. What happened to render the notion that talking to people about their experiences and helping them find jobs or go back to school is something novel?

I believe that an Intensive Psychotherapy can lead to healing and, often, a cure of psychotic states. By cure I mean the cessation of delusions and hallucinations, and a gradual titration off of antipsychotic medication, with the cure lasting—even without continuing psychotherapy.

Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.

Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.

Statistics from the UK reveal that prescriptions for painkillers and antidepressants continue to rise despite concerns over dependence and debilitating withdrawal effects. The British Medical Association (BMA) Board of Science has released a report that acknowledges changes to medical practice, research and policy necessary for addressing the dependence and withdrawal effects of benzodiazepines, opioids, and antidepressants.