Antidepressants Do Not Prevent Suicides, May Increase Risk

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When the CDC released data revealing an increasing suicide rate in the US, some experts, speaking to major media outlets, speculated that the increase...

Antidepressants Linked to Lasting Sexual Dysfunction, Study Finds

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New research highlights the challenges in quantifying the prevalence of Post-SSRI Sexual Dysfunction (PSSD), a condition that continues to affect patients long after they stop taking antidepressants.

Did Psychiatry Ever Endorse the Chemical Imbalance Theory of Depression?

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With the chemical imbalance theory falling out of fashion, researchers examine the claim that psychiatry never truly endorsed it.

Overuse of Psychiatric Drugs is Worsening Public Mental Health, Doctor Argues

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A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.

Understanding the Neurobiology of Post-SSRI Sexual Dysfunction

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Post-SSRI sexual dysfunction (PSSD) may be a common adverse effect of antidepressants. Researchers are now attempting to understand the neurobiology behind it.
veteran suicides

Screening + Drug Treatment = Increase in Veteran Suicides

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For the past 15 years, the VA's suicide prevention efforts have focused on getting veterans screened and treated for psychiatric disorders, with antidepressants a first-line therapy. This effort has caused veteran suicide rates to steadily rise.
VA Secretary Robert Wilkie

An Open Letter to VA Secretary Robert Wilkie: A Plan for Deprescribing Veteran Suicides

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Through my research and experiences, I've found that what the Veterans Administration has been doing to fight the veteran suicide epidemic isn't working and appears to be unintentionally exacerbating it. These problems are fixable. But I need your help.

How to Distinguish Antidepressant Withdrawal from Relapse

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Mark Horowitz and David Taylor provide advice on how to tell the difference between antidepressant withdrawal and depression relapse.

What Is the Risk of Permanent Sexual Dysfunction from Antidepressants?

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Males taking antidepressants were at 100 times the risk of erectile dysfunction compared with the healthy population and more than three times the risk even after controlling for other variables.

Giovanni Fava – A Different Psychiatry is Possible

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In this podcast, we hear from the renowned clinician and researcher Dr. Giovanni Fava about his latest book entitled “Discontinuing Antidepressant Medications”.

New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”

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A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”

Antidepressant Use Leads to Worse Long Term Outcomes, Study Finds

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Results from a 30-year prospective study demonstrated worse outcomes for people who took antidepressants, even after controlling for gender, education level, marriage, baseline severity, other affective disorders, suicidality, and family history of depression.
3D render of placebo pills isolated over wood background

Placebo Effect—Not Antidepressants—Responsible for Depression Improvement

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In adolescent depression treatment, those who received a placebo but thought they received Prozac improved more than those who received the drug and knew it.
Top View of Girl Sits on Bed with Scattered Pills. Little Child Sitting on Gray Badcover Near Opened Packing of Medicines Keeps Head with Hands. Unhappy Childhood Concept

Antidepressants Increase Suicide Attempts in Youth; No Preventative Effect

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Researchers find that SSRIs increase suicide attempts up to age 24, and have no preventative effect at any age, even for those at high risk of suicide.

William Styron: His Struggles with Psychiatry and Its Pills

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Author William Styron is often remembered for speaking about depression as an illness. But a review of his life reveals that psychiatric drugs may have triggered and even worsened his depressive episodes.

Antidepressants Overprescribed to Post-Menopausal Women Despite Risks

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A new study reveals that antidepressants, commonly prescribed to post-menopausal women, may increase risks of falls, cognitive decline, and cardiovascular issues, raising questions about their overuse in this population.

Zoloft Does Not Improve Depression, Even in Severe Cases, Study Finds

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Despite their finding, the researchers suggest that SSRIs be given to people who do not meet criteria for depression or anxiety.

Antidepressant Trials “Hijacked for Marketing Purposes,” Researchers Say

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About half of the large antidepressant trials are biased enough to be considered “seeding trials,” according to the researchers.
Illustration of a shape of a baby crawling made out of various types of pills, on a black background

Health Risks to Babies When Antidepressants Used During Pregnancy

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Babies born to mothers taking antidepressants during pregnancy were more than six times as likely to have neonatal withdrawal syndrome—including breathing problems, irritability/agitation, tremors, feeding problems, and seizures—than those born to mothers taking other types of drugs.

The Whistleblower and Penn: A Final Accounting of Study 352

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After 18 years, the full story of the scientific corruption in a study of paroxetine for bipolar disorder, and the psychiatrist who blew the whistle.

Newborn Babies Go Through Antidepressant Withdrawal

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A new study finds that newborn babies experience antidepressant withdrawal after birth if their mothers take SSRIs when pregnant.

Withdrawal Symptoms Common for Those who Stop Taking Antidepressants

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A new study, published in Molecular Psychiatry, investigates the prevalence and typical characteristics of antidepressant withdrawal syndrome (AWS) through analyzing available research. Researchers found...

Antidepressant Misinformation Promoted on Popular Websites

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A new study indicates that popular online resources do not accurately present the scientific evidence on the risks and benefits of antidepressants.

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

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A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

New Data Reveal the Full Extent of STAR*D Failure

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The initial study, which has been used to promote antidepressants, employed outcome switching to hide poor results.