Understanding the Neurobiology of Post-SSRI Sexual Dysfunction
Post-SSRI sexual dysfunction (PSSD) may be a common adverse effect of antidepressants. Researchers are now attempting to understand the neurobiology behind it.
Did Psychiatry Ever Endorse the Chemical Imbalance Theory of Depression?
With the chemical imbalance theory falling out of fashion, researchers examine the claim that psychiatry never truly endorsed it.
Overuse of Psychiatric Drugs is Worsening Public Mental Health, Doctor Argues
A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.
Lexapro for Children: Drug With No Meaningful Benefit and Increased Suicidality Gets FDA Approval
Response and remission rates were the same in the drug versus placebo groups, and Lexapro increased suicidality sixfold.
Antidepressants Linked to Lasting Sexual Dysfunction, Study Finds
New research highlights the challenges in quantifying the prevalence of Post-SSRI Sexual Dysfunction (PSSD), a condition that continues to affect patients long after they stop taking antidepressants.
New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmfulā
A new study published in Frontiers in Psychiatry concludes that āantidepressants are largely ineffective and potentially harmful.ā
Screening + Drug Treatment = Increase in Veteran Suicides
For the past 15 years, the VA's suicide prevention efforts have focused on getting veterans screened and treated for psychiatric disorders, with antidepressants a first-line therapy. This effort has caused veteran suicide rates to steadily rise.
An Open Letter to VA Secretary Robert Wilkie: A Plan for Deprescribing Veteran Suicides
Through my research and experiences, I've found that what the Veterans Administration has been doing to fight the veteran suicide epidemic isn't working and appears to be unintentionally exacerbating it. These problems are fixable. But I need your help.
What Is the Risk of Permanent Sexual Dysfunction from Antidepressants?
Males taking antidepressants were at 100 times the risk of erectile dysfunction compared with the healthy population and more than three times the risk even after controlling for other variables.
William Styron: His Struggles with Psychiatry and Its Pills
Author William Styron is often remembered for speaking about depression as an illness. But a review of his life reveals that psychiatric drugs may have triggered and even worsened his depressive episodes.
Placebo EffectāNot AntidepressantsāResponsible for Depression Improvement
In adolescent depression treatment, those who received a placebo but thought they received Prozac improved more than those who received the drug and knew it.
How to Distinguish Antidepressant Withdrawal from Relapse
Mark Horowitz and David Taylor provide advice on how to tell the difference between antidepressant withdrawal and depression relapse.
NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal
A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.
Antidepressant Trials āHijacked for Marketing Purposes,ā Researchers Say
About half of the large antidepressant trials are biased enough to be considered āseeding trials,ā according to the researchers.
Antidepressant Use Leads to Worse Long Term Outcomes, Study Finds
Results from a 30-year prospective study demonstrated worse outcomes for people who took antidepressants, even after controlling for gender, education level, marriage, baseline severity, other affective disorders, suicidality, and family history of depression.
Less Than a Quarter of Those with Depression Respond to Treatment in Real Life
In a real-world setting, less than a quarter of patients diagnosed with depression improved with medication, hospitalization, and therapy.
Antidepressants Increase Suicide Attempts in Youth; No Preventative Effect
Researchers find that SSRIs increase suicide attempts up to age 24, and have no preventative effect at any age, even for those at high risk of suicide.
Giovanni Fava – A Different Psychiatry is Possible
In this podcast, we hear from the renowned clinician and researcher Dr. Giovanni Fava about his latest book entitled āDiscontinuing Antidepressant Medicationsā.
New Research Questions Safety of Esketamine for Depression
An analysis of FDA adverse event reports related to esketamine shows the potential for negative effects such as suicidal and self-injurious ideation.
Researchers: It’s Time to Stop Recommending Antidepressants for Depression
Researchers review a new synthesis of the existing evidence and conclude that the harms of antidepressants outweigh any benefits.
Antidepressants Overprescribed to Post-Menopausal Women Despite Risks
A new study reveals that antidepressants, commonly prescribed to post-menopausal women, may increase risks of falls, cognitive decline, and cardiovascular issues, raising questions about their overuse in this population.
Withdrawal Symptoms Common for Those who Stop Taking Antidepressants
A new study, published in Molecular Psychiatry, investigates the prevalence and typical characteristics of antidepressant withdrawal syndrome (AWS) through analyzing available research. Researchers found...
Prescribing an Epidemic: A Veteranās Story
Had I known what I know now, I never would have taken any of these drugs, and I absolutely would not have taken a role in which my outreach efforts to get veterans into mental health treatment might place thousands of lives at risk.
The Whistleblower and Penn: A Final Accounting of Study 352
After 18 years, the full story of the scientific corruption in a study of paroxetine for bipolar disorder, and the psychiatrist who blew the whistle.
Internet Forum for Tapering Psychiatric Drugs Provides Novel Insights
After 15 years, the founder of SurvivingAntidepressants.org, Adele Framer, shares what she has learned about the science of withdrawing from psychiatric drugs.
