Antidepressants

Researchers from Australia find that chronic treatment with SSRIs significantly increases the rate of epileptogenesis in rats.  Although SSRIs are commonly prescribed to people...

Infants exposed to SSRIs and benzodiazepines during pregnancy show impaired neurologic functioning in the first month after birth, according to a new study published in the American Journal of Psychiatry. While infants exposed SSRIs alone showed neurobehavioral effects throughout the first month, those exposed to an SSRI and a benzodiazepine had more significant problems.

STAT recently published an opinion piece arguing that the black box warning on antidepressants has led to an increase in adolescent suicide. It is easily debunked, and reveals once again how our society is regularly misled about research findings related to psychiatric drugs. STAT has lent its good name to a false story that, unfortunately, will resonate loudly with the public.

“It’s hap­pening," said researchers at Northeastern University, "Kids are becoming irri­tated, aggres­sive, impul­sive, agi­tated, hos­tile. So you ask the ques­tion: Why?” They found (through study...

When the CDC released data revealing an increasing suicide rate in the US, some experts, speaking to major media outlets, speculated that the increase...

Continuing to take antidepressants during pregnancy was associated with higher rates of depressive relapses and hospitalizations than discontinuing.

Research sheds light on the impact of antidepressants on sexual dysfunction, emphasizing the need for patient-physician communication.

Antidepressant trials with negative results are still more likely than not to either be misleadingly spun as positive or unpublished.

A new study investigated whether participants guessing if they have an antidepressant or placebo affects response rates.

Recent claims about antidepressant effectiveness have been based on misleading statements and misunderstandings of the science.

A new study suggests that taking antidepressants impairs empathy, while the experience of depression itself does not.

Researchers found that 25% of elderly patients taking antidepressants had serotonin syndrome, which is potentially life-threatening.

A study comparing the effects on cognition of major depression (MDD) vs. SSRIs finds that healthy subjects learn significantly better from positive feedback than...

We interview Dr. Stuart Shipko, a psychiatrist and author who has a particular interest in the side effects and withdrawal effects of SSRI antidepressants and the need for informed consent when prescribing.

Researchers, publishing in Toxicology Research, review the evidence that antidepressant exposure in the womb is linked to autism spectrum disorders (ASD) in humans.

Study finds antidepressant use is linked to increase in hip fractures in community-dwelling older adults with and without Alzheimer’s disease.

A systematic review of literature and meta-analysis indicates that there is no clinically or statistically significant effect of antidepressant dose increase after nonresponse to initial treatment.

An article by written by faculty of the Harvard History of Science Department and the Program in Placebo Studies explores how "drug marketing portrays...

People who take SSRI antidepressants are twice as likely to have their dental implants fail, according to McGill University researchers. In a press release,...

New research, based on data from almost a million children in Denmark, suggests that children of mothers who use antidepressants during pregnancy are more likely to be diagnosed with autism and psychiatric disorders.

Researchers suggest that because most antidepressant “success” is due to the placebo effect, they may never find a way to predict outcomes.

A new study found that taking antidepressants did not improve quality of life.

Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

Scientists at Microsoft, Stanford and Columbia University, using automated software to mine data from 82 million internet searches for information related to, found a...

The use of antidepressants has risen quickly among older adults but the rate of depressive symptoms in this population has not declined as a result.