Wednesday, September 23, 2020

Inappropriate Use of Antipsychotics on Adults with Intellectual and Developmental Disabilities

One-third of adults with an intellectual or developmental disability are dispensed antipsychotics, despite having no existing psychiatric diagnosis.

Increased Risk of Movement Disorders From Antipsychotics in Persons with Intellectual Disabilities

Large cohort study demonstrates that those with an intellectual disability are at an increased risk for movement disorder side effects of antipsychotics.

Patients With Schizophrenia Show Better Work Functioning Off Antipsychotics

20-year follow-up study finds that after four years, patients not prescribed antipsychotics have significantly better work functioning.

In Chronic Patients, Antipsychotics Have Limited Efficacy in Reducing Symptoms

A large review and meta-analysis of 167 studies across 60 years dissects placebo-controlled randomized controlled trials of antipsychotic drugs.

Half of First-Episode Patients Respond to Antipsychotics

No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.

Large Study Confirms Elevated Risk of Diabetes When Prescribed Antipsychotics

A large longitudinal study finds once more that being prescribed antipsychotics significantly increases the risk of diabetes.

Study Shows Clozapine Can Result in Serious Gastrointestinal Complications

A large observational study published in CNS Drugs sheds light on serious adverse effects of the ‘gold standard’ antipsychotic Clozapine.

Psychiatry Defends Its Antipsychotics: A Case Study of Institutional Corruption

Jeffrey LIeberman and colleagues have published a paper in the American Journal of Psychiatry stating that there is no evidence that psychiatric drugs cause long-term harm, and that the evidence shows that these drugs provide a great benefit to patients. A close examination of their review reveals that it is a classic example of institutional corruption, which was meant to protect guild interests.

Study Explores Cognitive Effects of Antipsychotics

Reduced usage of antipsychotics in first-episode psychosis was associated with improved executive functioning.

Danish Study Finds Better 10-year Outcomes in Patients Off Antipsychotics

Study finds that 74% of patients with a psychotic disorder off antipsychotics at end of 10 years are in remission.

Acute Respiratory Failure More Likely in COPD Patients Prescribed Antipsychotics

Researchers recommend that healthcare professionals be vigilant regarding the signs of respiratory failure among patients with COPD who are receiving antipsychotics, especially during the initial treatment phase.

Mental Health Nurses Do Not Routinely Assess for Effects of Antipsychotic Medications

Researchers believe that side-effect monitoring is critical because of the increase in the use of antipsychotics

Withdrawal from Antipsychotics

A review of the scientific literature related to the withdrawal of antipsychotics: animal studies, withdrawal symptoms, tapering success rates, and consumer accounts of discontinuation.

Study Suggests Long-Term Antipsychotic Use May Result in Poorer Cognitive Functioning

Association found between long-term antipsychotic use and poorer performance on cognitive tasks in adults diagnosed with ‘schizophrenia.’

Review Questions Long Term Use of Antipsychotics

Patients who recover from a single episode of psychosis are often prescribed antipsychotics long-term, despite a lack of evidence for this practice

Safety Analysis Weighs Harms and Benefits of Antipsychotic Drugs

The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.

A Guide to Minimal Use of Neuroleptics

This guide, by psychiatrists Volkmar Aderhold and Peter Stastny, provides a comprehensive review of antipsychotics and an evidence-based rationale for avoiding their use in first-episode psychosis, and for minimizing their long-term use.

Study Finds Improved Functioning for ‘Schizophrenia’ Without Antipsychotics

Long-term treatment with antipsychotic drugs is currently considered the standard treatment for patients diagnosed with ‘schizophrenia.’ A new study challenges this practice, however. The...

The Case Against Antipsychotics

This review of the scientific literature, stretching across six decades, makes the case that antipsychotics, over the long-term, do more harm than good. The drugs lower recovery rates and worsen functional outcomes over longer periods of time.

Researchers Discover How Antipsychotics Lead To Parkinsonism

A new study published this month in the journal Neuron identifies the mechanism by which antipsychotic drugs can induce parkinsonism, a condition involving movement...

Review Links Antipsychotics with Risk for Heart Attacks

A systematic review published this week in the British Journal of Clinical Pharmacology found that patients taking antipsychotic drugs were at nearly twice the risk...

Olanzapine Can Cause Serious Skin Reaction, FDA Warns

The US FDA has issued a new warning for the atypical antipsychotic Olanzapine, also known by the brand names Zyprexa and Symbyax. The agency...

FDA Warns About New Impulse-Control Problems Associated With Abilify

Yesterday, the US Food and Drug Administration (FDA) released a warning that the antipsychotic drug aripiprazole or Abilify is associated with compulsive and uncontrollable...

Antipsychotics Increase Mortality Risk in Patients with Parkinson’s Disease

A new study in JAMA Neurology finds that the use of antipsychotic drugs more than doubled the risk of death in patients with Parkinson’s...

Researchers Call for Reappraisal of Adverse Mental Effects of Antipsychotics, NIDS

In a study published yesterday, researchers from the Nippon Medical School in Tokyo bring attention to a condition known as neuroleptic-induced deficit syndrome (NIDS)...

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