Withdrawal from Mood Stabilizers

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A review of the scientific literature for withdrawal from mood stabilizers: mechanism of action, animal studies, withdrawal symptoms, discontinuation success rates, and relapse rates related to tapering speeds.

Withdrawal from Antipsychotics

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A review of the scientific literature related to the withdrawal of antipsychotics: animal studies, withdrawal symptoms, tapering success rates, and consumer accounts of discontinuation.

Withdrawal from Antidepressants

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A review of the scientific literature related to withdrawal from antidepressants: mechanism of action; long-term effects of exposure to antidepressants; discontinuation syndromes; relapse upon discontinuation; tapering protocols.

Withdrawal from ADHD Medications

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This guide to the scientific literature on withdrawal from ADHD drugs provides a review of animal studies, withdrawal syndromes, and possible tapering protocols.

Study Suggests Long-Term Antipsychotic Use May Result in Poorer Cognitive Functioning

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Association found between long-term antipsychotic use and poorer performance on cognitive tasks in adults diagnosed with ‘schizophrenia.’

Review Questions Long Term Use of Antipsychotics

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Patients who recover from a single episode of psychosis are often prescribed antipsychotics long-term, despite a lack of evidence for this practice

FDA Safety Warning For Citalopram Did Not Improve Outcomes for Vets

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Instead of reducing risk, the dose reduction recommendation made by the FDA in their safety message was associated with an increase in hospitalizations.

Safety Analysis Weighs Harms and Benefits of Antipsychotic Drugs

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The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.

Exploring Psychiatry’s “Black Hole”: The International Institute on Psychiatric Drug Withdrawal

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When Carina Håkansson sent out an invitation for a symposium on "Pharmaceuticals: Risks and Alternatives," some of the world's top scientists, along with experts-by-experience, came from 13 countries to explore better ways to respond to people in crisis.

When Psychiatric Medications Cause Psychiatric Symptoms

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Dr. Yolande Lucire, a psychiatrist from Australia, recently published a paper about the iatrogenic effects of psychiatric drugs.

What Animal Research Says About Sexual Side-effects of SSRIs

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A group of researchers in Denmark examines what existing animal studies can tell us about the sexual side-effects of SSRI antidepressants.

Antidepressant Use Linked to Dementia

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A new study finds that elderly individuals using antidepressants are at significantly higher risk for dementia compared to depressed individuals who did not take the drugs.

Study Finds Antidepressants in Pregnancy Increase Risk for Speech Disorders

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A new study published this week in JAMA Psychiatry indicates that infants are more likely to develop speech or language disorders if they are exposed to antidepressants during pregnancy.

Hypnotic Medications Linked to Suicide Risk

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A recent review found that hypnotic medications are associated with risks of suicide and suicidal ideation.

Systematic Review Finds Antidepressants Double the Risk for Agitation and Violence in Healthy Volunteers

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The Nordic Cochrane Center conducted a systematic review of existing research trials on antidepressants and found that the drugs doubled the risk of feelings...

Use of Antidepressants Linked to Diabetes

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Selective serotonin reuptake inhibitors (such as Prozac and Zoloft) are the most commonly prescribed medication for depression. SSRIs have long been associated with an...

Clinical Trials Underreport Harms of Antidepressant Medications

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A group of researchers recently found serious bias in the reporting of harm due to adverse events in antidepressant medication clinical trials. They report...

Antidepressants in Pregnancy: Risks to the Fetus and Long-term Health of the Child

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The research literature reveals that antidepressant use in pregnancy poses considerable risks to the fetus and the long-term health of the child. These risks include preterm birth, birth defects, abnormal brain development, and behavioral abnormalities in early childhood.

A Guide to Minimal Use of Neuroleptics

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This guide, by psychiatrists Volkmar Aderhold and Peter Stastny, provides a comprehensive review of antipsychotics and an evidence-based rationale for avoiding their use in first-episode psychosis, and for minimizing their long-term use.

How Do Antidepressants Really ‘Work’?

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A recent review, published in Neuroscience & Biobehavioral Reviews, challenges the dominant assumptions about the neurochemical and therapeutic effects of Selective Serotonin Reuptake Inhibitors...

Antidepressant Effects Thwarted by Stressful Environments

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A new study, about to be published in the journal Brain, Behavior, and Immunity, investigates the role a stressful environment plays in antidepressant effectiveness....

German Psychologists Declare “the Drugs Don’t Work”

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Jürgen Margraf and Silvia Schneider, both well-known psychologists at the University of Bochum in Germany, claim that psychotropic drugs are no solution to mental...

STOP or GO? Tapering Pregnant Women off of Antidepressants

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A team in the Netherlands is currently investigating the effects of tapering off of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) during pregnancy....

The ADHD Drug Epidemic: Addiction, Abuse, and Death

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A new analysis of FDA data, published on September 10th by the Milwaukee Journal Sentinel/MedPage Today, reveals the dangers of the common prescription of...

Review Calls for Critical look at Prescribing Antidepressant Drugs

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The August issue of Psychotherapy and Psychosomatics published a review conducted by André F. Carvalho and colleagues regarding the literature around the long-term use...