Tuesday, February 7, 2023
Vector-style illustration depicting men and women chained to a giant pill bottle

Researchers Identify Factors to Predict Risk of Antidepressant Withdrawal

2
Paroxetine, SNRIs, and MAOIs were associated with the highest risk of withdrawal, as was long duration of use and whether the person experienced withdrawal in the past.

Common Statistical Method Conflates Withdrawal with Relapse

4
Researchers argue that common study methods for psychiatric drugs may inadvertently minimize withdrawal effects and inflate drug efficacy.
Picture of distressed man facing pills

What Helps Long-Term Users of Benzodiazepines and Z-Drugs Discontinue?

3
Current long-term users of benzodiazepines and Z-drugs identify barriers and facilitators for discontinuation.

Researchers Provide Guidance for Reducing and Stopping Psychiatric Drugs

28
New guidance on how to taper and discontinue from psychiatric drugs from leading researchers Mark Horowitz and David Taylor.

Tapered Antipsychotic Withdrawal Mitigates Risk of Psychotic Symptoms

15
Research suggests that slowly tapering off an antipsychotic reduces the risk of withdrawal psychosis compared to abrupt discontinuation.

“Relapse” in Antidepressant Trials Likely Caused by Sudden Withdrawal

3
A new study investigates how antidepressant withdrawal effects often get confounded with depression relapse in clinical trials.

Psychotherapy Can Prevent Relapse When Discontinuing Antidepressants

15
“Short and simple psychological programs can prevent people from relapsing when they stop their antidepressants.”

Internet Forum for Tapering Psychiatric Drugs Provides Novel Insights

2
After 15 years, the founder of SurvivingAntidepressants.org, Adele Framer, shares what she has learned about the science of withdrawing from psychiatric drugs.

Antidepressant Withdrawal Misdiagnosed as Functional Disorder

15
Adverse physiological symptoms of antidepressant withdrawal are regularly mistaken to be other problems to the detriment of the patient.

Online Experts on Withdrawal

18
Online communities are stepping in to help people facing withdrawal effects amass information and receive support for their withdrawal experiences.

Researchers Document Protracted Withdrawal from Antidepressants

1
Protracted Withdrawal Syndrome characterized by long-term adverse experiences after coming off of antidepressants.

Facebook Groups Provide Psychiatric Drug Withdrawal Help When Doctors Don’t

7
A new study looks at how online communities provide information and support for patients experiencing psychiatric drug withdrawal.

Listening to the Patient Voice: The Antidepressant Withdrawal Experience

24
Patient advocates join with researchers and service users to present first-hand experiences of antidepressant withdrawal.
Correnn Stormcrow-And I Drown-Flickr

Literally Indescribable: Are Antidepressants Addictive?

24
“My life was very, very good.” That’s how Michael sums up how things were for him—prior to his suffering from devastating withdrawal effects after discontinuing GlaxoSmithKline’s blockbuster drug Paxil.

New FDA Study Shows Benzodiazepines Can Cause Long-Term Injury

41
The FDA has finally acknowledged the adverse effects of benzodiazepines, the dangers of withdrawal, and that the current packaging does not sufficiently warn of these harms.

Surviving Antidepressants: An Interview with Adele Framer

22
That is the truth about withdrawal syndrome: It’s like a 50-50 chance that you’re going to have a problem. If you’re in the unlucky half, you’re gonna be really unlucky.

Psychiatry’s Top Experts Acknowledge Lasting Harms of Antidepressant Withdrawal

7
Royal College of Psychiatrists’ former president demands support for patients coming off antidepressants.

Tapering Strips Help People Stop Using Antidepressants, Study Finds

7
A new study by Peter Groot and Jim van Os investigated whether tapering strips can help people stop using antidepressants.

Very Slow Taper Best for Antipsychotic Discontinuation

12
An article in JAMA Psychiatry advises very slow tapering for best results when discontinuing antipsychotic drugs.

Strategies for Tapering and Discontinuing Antidepressants

5
A new review of strategies to support both patients and practitioners through the process of discontinuing antidepressants.

Service-User Knowledge Helps Researchers Develop Psychiatric Drug Tapering Approaches

9
New strategies for tapering psychiatric drugs achieved by acknowledging withdrawal symptoms and valuing service-users’ first-hand knowledge.

Review Documents Severe Withdrawal Effects of Psychiatric Drugs

14
Researchers find that most psychiatric drugs cause severe withdrawal despite attempt s to gradually decrease the dosage.

Neuropsychological Tests Reveal Consequences of Polypharmacy

13
Neuropsychological assessments reveal the cognitive, occupational, and social impact of polypharmacy in psychiatry.

Researchers: Antidepressant Withdrawal, Not “Discontinuation Syndrome”

20
Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.

Prescribing an Epidemic: A Veteran’s Story

14
Had I known what I know now, I never would have taken any of these drugs, and I absolutely would not have taken a role in which my outreach efforts to get veterans into mental health treatment might place thousands of lives at risk.