Withdrawal Research Studies

Peer-Support Groups Were Right, Guidelines Were Wrong: Dr. Mark Horowitz on Tapering Off Antidepressants

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In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.

Surviving Antidepressants: An Interview with Adele Framer

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That is the truth about withdrawal syndrome: It’s like a 50-50 chance that you’re going to have a problem. If you’re in the unlucky half, you’re gonna be really unlucky.

Study Highlights Difficulty of Antipsychotic Withdrawal

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New research finds insomnia, anxiety, and depression are common symptoms of antipsychotic withdrawal, highlighting difficulties of discontinuation.
Pattern of blue and yellow pills or tablets on a pink background. concept of medicine, pharmacy and coronavirus. copy space

SSRI Withdrawal has Social, Cognitive, and Emotional Consequences

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New research finds that the non-physical aspects of withdrawal from SSRIs are often overlooked.
sertraline antidepressant withdrawal

Ambushed by Antidepressant Withdrawal: The Escape Story

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I’m alive. More than 30,000 veterans in the past decade alone are not. I was not warned of the risks of this drug. I was not told that once on it, I might never be able to get off it, or the nightmare that would ensue when I tried. I know millions of others were not told either.

Stopping SSRI Antidepressants Can Cause Long, Intense Withdrawal Problems

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In the first systematic review of withdrawal problems that patients experience when trying to get off SSRI antidepressant medications, researchers found that withdrawing from SSRIs was comparable to trying to quit addictive benzodiazepines.

Medication-Free Treatment in Norway: A Private Hospital Takes Center Stage

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At the Hurdalsj√łen Recovery Center in Norway, patients with a long history of psychiatric hospitalizations are tapering from their medications and, in a therapeutic environment that emphasizes a good diet, exercise, and asking patients "what do they want in life," are leaving their old lives as chronic patients behind.

New FDA Study Shows Benzodiazepines Can Cause Long-Term Injury

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The FDA has finally acknowledged the adverse effects of benzodiazepines, the dangers of withdrawal, and that the current packaging does not sufficiently warn of these harms.

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

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A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

Prescribing an Epidemic: A Veteran’s Story

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Had I known what I know now, I never would have taken any of these drugs, and I absolutely would not have taken a role in which my outreach efforts to get veterans into mental health treatment might place thousands of lives at risk.

Review Documents Severe Withdrawal Effects of Psychiatric Drugs

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Researchers find that most psychiatric drugs cause severe withdrawal despite attempt s to gradually decrease the dosage.

Withdrawal from ADHD Medications

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This guide to the scientific literature on withdrawal from ADHD drugs provides a review of animal studies, withdrawal syndromes, and possible tapering protocols.

Withdrawal from Benzodiazepines

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A review of the scientific literature related to withdrawal from benzodiazepines, including studies of protracted withdrawal symptoms and risk of relapse related to tapering procedures.

Very Slow Tapering Best For Antidepressant Withdrawal

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A new article in Lancet Psychiatry finds that slower tapering of SSRIs is better for preventing antidepressant withdrawal effects.

Psychiatry’s Top Experts Acknowledge Lasting Harms of Antidepressant Withdrawal

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Royal College of Psychiatrists’ former president demands support for patients coming off antidepressants.
the new yorker

The New Yorker Peers into the Psychiatric Abyss… And Loses Its Nerve

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The New Yorker's story on Laura Delano and psychiatric drug withdrawal is a glass-half-full story: It addresses a problem in psychiatry and yet hides the deeper story to be told. A story of how her recovery resulted from seeing herself within a counter-narrative that tells of the harm that psychiatry can do.

Very Slow Taper Best for Antipsychotic Discontinuation

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An article in JAMA Psychiatry advises very slow tapering for best results when discontinuing antipsychotic drugs.

Withdrawal from Mood Stabilizers

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A review of the scientific literature for withdrawal from mood stabilizers: mechanism of action, animal studies, withdrawal symptoms, discontinuation success rates, and relapse rates related to tapering speeds.

Withdrawal from Antidepressants

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A review of the scientific literature related to withdrawal from antidepressants: mechanism of action; long-term effects of exposure to antidepressants; discontinuation syndromes; relapse upon discontinuation; tapering protocols.

Researchers Provide Guidance for Reducing and Stopping Psychiatric Drugs

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New guidance on how to taper and discontinue from psychiatric drugs from leading researchers Mark Horowitz and David Taylor.

Researchers: Antidepressant Withdrawal, Not ‚ÄúDiscontinuation Syndrome‚ÄĚ

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Researchers suggest that the pharmaceutical industry had a vested interest in using the term ‚Äúdiscontinuation‚ÄĚ in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.

Antidepressant Withdrawal Misdiagnosed as Functional Disorder

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Adverse physiological symptoms of antidepressant withdrawal are regularly mistaken to be other problems to the detriment of the patient.

Gradual Tapering is Most Successful for Withdrawal from Antipsychotics

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Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.

Psychotherapy Can Prevent Relapse When Discontinuing Antidepressants

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‚ÄúShort and simple psychological programs can prevent people from relapsing when they stop their antidepressants.‚ÄĚ
Vector-style illustration depicting men and women chained to a giant pill bottle

Researchers Identify Factors to Predict Risk of Antidepressant Withdrawal

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Paroxetine, SNRIs, and MAOIs were associated with the highest risk of withdrawal, as was long duration of use and whether the person experienced withdrawal in the past.