The Power of Placebo is Strengthened by Having a Warm and Competent Practitioner
The effect of individual expectations on treatment outcomes is found to be influenced by physician attributes.
SSRI Ineffective at Treating Depression in Individuals with Chronic Kidney Disease
Dr. Madhukar Trivedi and colleagues find that the SSRI sertraline does not reduce depressive symptoms any more than placebo in people with Chronic Kidney Disease.
Rigorous Study Finds Antidepressants Worsen Long-Term Outcomes
A new study conducted by Jeffrey Vittengl at Truman University has found that taking antidepressant medications resulted in more severe depression symptoms after nine years.
Antidepressant Use May Increase Risk of Diabetes
New study confirms previous evidence that antidepressant use is linked to developing type 2 diabetes.
Researchers Confirm That Relative Age Impacts ADHD Diagnosis
The youngest children in a class are more likely to receive an ADHD diagnosis than their peers.
New Research Documents Widening Mortality Gap for Bipolar and Schizophrenia
Analysis of longitudinal data from 2000-2014 demonstrate mortality gap is widening between persons with a diagnosis of bipolar or schizophrenia compared to the general population
Antidepressants Increase Risk of Death, Study Finds
Antidepressants are commonly considered safe and effective treatments. However, research has questioned their efficacy, and now, their safety.
Challenges in Measuring Low-Value Healthcare
Differences in patient-centric versus service-centric measures make quantifying low-value care difficult.
Stimulant Medication Use Linked to Sharp Increase in BMI by Eighth Grade
New evidence suggests that children on ADHD medication may have stunted growth initially but more rapid increases in body mass over time.
Review Finds Little Evidence that Electroconvulsive Therapy is Effective for Depression
Researchers examined the dearth of support for Electroconvulsive therapy (ECT) for depressive symptoms in light of studies detailing the associated risks.
Thou Shall Not Criticize Our Drugs
A medical journal is expected to promote an open-minded discussion of treatments, even if findings—or criticisms—threaten conventional beliefs. But the American Journal of Psychiatry will not find space for criticism even if it comes from one of the best-known psychiatrists in the world.
More Follow Up Needed for Drugs Granted Accelerated FDA Approval
Drugs to treat serious or life-threatening conditions can receive accelerated FDA approval, but may expose patients to increased safety risks and reduced efficacy.
Replacing Pain with Pain: Hazards of Antidepressant Use for Chronic Pain Relief
The paradox of relieving chronic pain with an antidepressant (and a new set of symptoms).
The Most Promoted Drugs are Those with Little Therapeutic Value, Study Finds
Majority of top-selling and most promoted drugs in Canada are rated as having very limited safety and efficacy.
Researchers Question Add-On Treatment for ‘Schizophrenia’
A common practice when antipsychotics are found to be ineffective for schizophrenia is to prescribe a second, additional psychoactive medication. Now, a new study suggests that this practice is not supported by the research.
Inappropriate Use of Antipsychotics on Adults with Intellectual and Developmental Disabilities
One-third of adults with an intellectual or developmental disability are dispensed antipsychotics, despite having no existing psychiatric diagnosis.
Ethical Failings in Experimental Drug Safety Trials
Leading human subjects ethics researcher questions exploitation of uninsured minorities in experimental drug trials.
Increased Risk of Movement Disorders From Antipsychotics in Persons with Intellectual Disabilities
Large cohort study demonstrates that those with an intellectual disability are at an increased risk for movement disorder side effects of antipsychotics.
Patients With Schizophrenia Show Better Work Functioning Off Antipsychotics
20-year follow-up study finds that after four years, patients not prescribed antipsychotics have significantly better work functioning.
Researchers Find Inadequate Reporting of the Dangers of Ketamine Treatment for Depression
Researchers report that dangerous side effects are not being adequately reported in the trials of ketamine for depression.
Prenatal Exposure to Psychotropic Medication Linked to Long Term Cognitive Impairment
School aged children exposed prenatally to psychotropic medication show poorer outcomes in cognitive ability.
Study Suggests Mania More Common in Psychosis When Antidepressants Used
A prospective cohort study of those labeled high risk for psychosis finds a higher prevalence of antidepressant use among those who develop manic symptoms.
In Chronic Patients, Antipsychotics Have Limited Efficacy in Reducing Symptoms
A large review and meta-analysis of 167 studies across 60 years dissects placebo-controlled randomized controlled trials of antipsychotic drugs.
New Study Asks Doctors About Barriers to Deprescribing
Researchers interviewed doctors about the barriers that prevent them from being able to decrease excess medications.
Half of First-Episode Patients Respond to Antipsychotics
No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.
