Drug Page

Study reviews psychological interventions for antidepressant discontinuation.

While most treatments have had "statistically significant" success in clinical trials, no common psychiatric or psychological treatments improve the negative symptoms of schizophrenia at levels that are "clinically meaningful."

Correcting unnecessary long-term antidepressant use is difficult and met with apprehension by providers and service-users.

The Scientific American reports on a new analysis of antidepressant trials revealing that the vast majority of meta-analyses have industry links and suppress negative results.

Organizations, advocates, scholars, and practitioners had a chance to give feedback regarding FDA processes.

The American Psychological Association (APA) recently published a study finding that patients assigned to drug-only treatments were more likely to refuse treatment, and more likely to drop out before treatment completion, than patients assigned to psychotherapy only.

The U.S. Preventive Services Task Force (USPSTF) recently issued a controversial recommendation that all adolescent and adult patients undergo depression screening in primary care. The...

A new paper, published in the British Medical Journal, explains how the pharmaceutical industry has publicly denounced ghostwriting while still finding ways to engage...

If academic psychiatry is evidence-based, why did it take two decades to recognize SSRI withdrawal as widespread and chronic among patients?

Important assessment tool found to underestimate the risk for fracture in patients on psychiatric medication.

A recent RCT showed that vitamin B6 is as effective as propranolol for the treatment of akathisia.

More than ten-percent of adults in the United States are currently prescribed at least one psychiatric medication but there is currently a lack of research on the prevalence of adverse drug events (ADEs) associated with these prescriptions outside of clinical trials.

The Psychiatric Advisor reports on new research from King’s College London that suggests that antipsychotics can cause serious harm to people with Parkinson’s.

Writing for the Atlantic, David Dobbs examines how much harm has been done in the 14 years since Paxil was wrongly determined to be safe and effective. “Study 329, as it became known, helped spur a huge increase in Paxil prescriptions,” Dobbs writes. “In 2002 alone, over 2 million prescriptions were written for children and teens, and many more for adults.” “Thousands of children, teens, and young adults attempted or committed suicide while on Paxil,” and the reanalysis of Study 329 in BMJ makes it seem “more likely than ever” that many did because of the drug.

Implementing policies that regulate pharmaceutical sales representatives’ interaction with physicians may reduce prescription of promoted drugs.

Primary care clinicians and mental health providers face a particular set of challenges when treating individuals with chronic pain. These problems are compounded by...

In part six of a seven-part “Drugging Our Kids” series by The Mercury News, Karen de Sa and Tracy Seipel unveil California’s top foster...

Recently, major researchers, including David Healy, Jon Juriedini, Mickey Nardo, and their colleagues, have brought a great deal of attention to issues of corruption...

Well known Stanford University researcher John Ioannidis published a new paper this week criticizing the use and production of systematic reviews and meta-analyses, often...

In 2004, the FDA added a black-box warning to SSRI antidepressants on the increased risk of suicide among children taking these drugs. A new study suggests that this warning has increased the proportion of children who begin an antidepressant on a low dose, but the majority are still receiving higher than recommended doses.

Contrary to widely-held belief, a new rigorous trial finds that ketamine is ineffective for delirium and pain associated with surgery, and the drug carries harmful side effects.

Wendy Dolin sued GSK after her husband committed suicide after taking a generic version of Paxil. The US District Court has declined GSK’s motions...

Drug Watch releases an in-depth investigation into the marketing practices of pharmaceutical companies in the United States. “Companies spend billions advertising to doctors to...

A former pharma executive has broken ranks with the industry in a new book by reporting how multiple psychiatrists, schools, and his desperate hopes pressed him to allow higher and higher doses of antipsychotic medications. The result: his 15-year-old son's death from Seroquel.

A team in the Netherlands is currently investigating the effects of tapering off of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) during pregnancy....