Ritalin Used to be “Grandma’s Little Helper”
Eugene Raikhel reveals ads from 1966 where Ritalin, now prescribed largely for ADHD, was marketed as a “kind of mind antidepressant for housewives.” “I...
CDC Advises Nonopioid Treatments for Chronic Pain
Primary care clinicians and mental health providers face a particular set of challenges when treating individuals with chronic pain. These problems are compounded by...
Fluoxetine Not Helpful for Children with Autism
A clinical trial finds Prozac no better than placebo for improving repetitive behaviors.
Benzodiazepine Use Linked to Dementia and Memory Loss
A recent review of the research found that benzodiazepine use may have long-term effects on memory and increase the risk for dementia. The study,...
Members of FDA Advisory Committee Offer Perspectives on Flibanserin Approval in JAMA
In the September issue of The Journal of the American Medical Association (JAMA) three FDA advisory committee members describe the convergence of factors that made the committee’s recommendation to approve flibanserin especially challenging and politically charged.
“Controversial ‘Female Viagra’ Hits the Market, New Questions Arise”
Despite concerns about the drug’s necessity, effectiveness, and side-effects, Flibanserin (Addyi) has come to market as the first drug designed to increase sexual desire in women
Has Evidence Based Medicine Been Hijacked?
John Ioannidis claims that the idea of evidence based medicine has been “hijacked to serve agendas different from what it was originally aimed for,” in a newly published critical essay in the Journal of Clinical Epidemiology. Ioannidis frames the essay as a continuation of a conversation with David Sackett, widely considered the founder of evidence based medicine.
Biogen Pushes FDA to Approve Failed Alzheimer’s Drug
A new analysis, published in Lancet Neurology, demonstrates how Biogen is spinning results from two failed trials for a new Alzheimer's drug.
Youngest Children in Class More Likely to get ‘ADHD’ Drugs
The researchers suggest that developmental immaturity is mislabelled as a mental disorder and unnecessarily treated with stimulant medication
Paxil Linked to Birth Defects, Cardiac Malformations
According to the CDC, January is National Birth Defects Prevention Month. New research continues to link various SSRI antidepressants with birth defects and neurological abnormalities in newborns. The latest study to examine this topic, a meta-analysis led by Dr. Anick Bérard, found a 23% increased risk for birth defects, and a 28% increased risk for heart problems, in the infants of women who took the SSRI Paxil (paroxetine) during their first trimester.
Depression: It’s Not Your Serotonin
What if I told you that, in 6 decades of research, the serotonin (or norepinephrine, or dopamine) theory of depression and anxiety - the claim that “Depression is a serious medical condition that may be due to a chemical imbalance, and Zoloft works to correct this imbalance” - has not achieved scientific credibility? You’d want some supporting arguments for this shocking claim. So, here you go:
Most People with Common ‘Mental Disorders’ Get Better Without Treatment, Study Finds
A new study suggests that most people diagnosed with depressive, anxiety, and substance abuse disorders recover without treatment within a year of diagnosis. “This...
Animal Study Supports Influence of Probiotics on Resilience to Stress
Researchers experimenting on mice found that Lactobacillus—the probiotic commonly found in yogurt—may help reduce depressive symptoms in reaction to chronic stressors. But human studies have found mixed results.
Antidepressant Misinformation Promoted on Popular Websites
A new study indicates that popular online resources do not accurately present the scientific evidence on the risks and benefits of antidepressants.
Mental Health Professionals and Patients Often Disagree on Causes of Symptoms
A new study finds that clinicians’ disregard for mental health patients’ insight into their own condition may be detrimental to treatment.
“More Evidence that Antipsychotics Shrink the Brain”
New research finds that brain matter loss in patients diagnosed with schizophrenia is correlated with antipsychotic use, according to Psych Central. The analysis suggests that the continued use of antipsychotics is linked with progressive cortical gray matter loss.
Prenatal Valproate Exposure Linked with ADHD Diagnosis in Children
Children who were exposed to anti-seizure drug valproate in utero were 48% more likely to develop ADHD, according to a new study.
Researchers: Antidepressant Withdrawal, Not “Discontinuation Syndrome”
Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.
Researchers Push Back Against Recommendation to Combine Antidepressants for Suicide Prevention
Researchers challenge the recommendation of starting two antidepressants simultaneously to increase preventative effects against suicide.
Outcome Reporting Bias in Antipsychotic Medication Trials
A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.
Failed TB Vaccine Exposes Concerns Regarding Research Ethics
An investigation exposes violations to research ethics, finding that researchers failed to disclose risks and even misled government agencies.
Latest Antidepressant a Case Study in Institutional Corruption
A new study tracks the approval of the latest antidepressant, vortioxetine, by the Federal Drug Administration (FDA) and the European Medicines Agency (EMA). The...
“Politicians and Experts Meet at Parliament to Explore Record Antidepressant Prescribing and Disability”
The All-Party Parliamentary Group for Prescribed Drug Dependence is meeting today, May 11th, to discuss evidence of the link between the rise in disability...
iPad Use Before Surgery as Effective as Sedatives for Children
A group of French doctors presented a new study in the area of pediatric anesthesiology at this year’s World Congress of Anaesthesiologists in Hong...
ADHD Drugs Linked to Psychotic Symptoms in Children
Stimulant medications like Ritalin and Adderall, often prescribed to treat children diagnosed with ADHD, are known to cause hallucinations and psychotic symptoms. Until recently these adverse effects were considered to be rare. A new study to be published in the January issue of Pediatrics challenges this belief, however, and finds that many more children may be experiencing psychotic symptoms as a result of these drugs than previously acknowledged.
