Thursday, November 26, 2020

Antipsychotic Trials Show Increasing Placebo Response and Declining Drug Response

A new review of antipsychotic trials conducted over the last 24 years finds that the placebo response rate is steadily increasing, and drug response is decreasing.

“Medicare Drug Program Fails to Monitor Prescribers, Putting Seniors and Disabled at Risk”

ProPublica and The Washington Post have performed an investigation revealing that Medicare has failed to monitor the safety of the large quantities of drugs...

PTSD and Antidepressants Linked to Diabetes

A JAMA Psychiatry study found links between PTSD, type 2 diabetes, and antidepressants.

1 in 6 Adults in the US Takes a Psychiatric Drug

Overall, 16.7% of 242 million US adults reported filling 1 or more prescriptions for psychiatric drugs in 2013.

The Evidence-Based Long-Term Treatment for Depression

While antidepressants are the most commonly used long-term treatment for depression, the efficacy of these drugs after one year is unknown. In a commentary for The Lancet, psychiatrists Rudolf Uher and Barbara Pavlova suggest that cognitive behavioral therapy (CBT) now has the most substantial body of evidence for long-term treatment for major depressive disorder.

RAISE Study Out Of Sync With Media Reports

Writing on his 1 Boring Old Man blog, Dr. Mickey Nardo reflects on the media frenzy around the RAISE study and asks why the prescription data has not been released. He adds skepticism about the political motives of the potentially overblown results, which he sees as a clear push for increased mental health funding.

Mindfulness Pain Relief Distinct from Placebo Effect

A new study demonstrates that the practice of mindfulness may ease pain in a way that is mechanistically distinct from the placebo effect. Research, published in the Journal of Neuroscience, found that mindfulness meditation not only outperformed placebo and fake meditation for pain relief but that it also activated different brain regions than the placebo treatments.

Psychotropic Medications Serve as Powerful Tools for U.S. Military, Imperialism

Ethnographic research sheds light on extensive psychopharmaceutical use by soldiers in post 9/11 U.S. wars.

Mental Health Disability Claims Continue to Climb

According to new research by Joanna Moncrieff and Sebastião Viola, mental health problems have become the leading cause of disability claims in the UK. While the overall number of claims for other conditions has decreased by 35%, claims related to “mental disorders” have increased 103% since 1995.

Many Teens Start Misusing Stimulants By Age 13

An equal percentage of young people will start misusing ADHD-related and other stimulant drugs for the first time at age 13 as will start at age 20.

New Study Asks Doctors About Barriers to Deprescribing

Researchers interviewed doctors about the barriers that prevent them from being able to decrease excess medications.

The ADHD Drug Abuse Crisis on College Campuses

The abuse of ADHD drugs on college campuses has reached epidemic proportions, according to the authors of a recent review in the journal of Ethical Human Psychology and Psychiatry. ADHD drugs, like Ritalin and Adderall, have become so commonplace on college campuses that students abusing these drugs for studying, weight loss and partying have underestimated their risks. As a result, we have seen exponential increases in emergency room visits, overdoses, and suicides by students taking these drugs.

What Animal Research Says About Sexual Side-effects of SSRIs

A group of researchers in Denmark examines what existing animal studies can tell us about the sexual side-effects of SSRI antidepressants.

Psychotropics Linked to Worse Physical Problems and Mortality in Psychiatric Patients

Common psychotropic medications may be contributing to the higher rates of physical illnesses and mortality in people diagnosed with mental illnesses.

Over 1,000 Antidepressant Users Describe how Their Personal Life has Been Affected

Survey examines adverse personal and interpersonal effects of antidepressants and the impact of polypharmacy

Psychiatric Medications Heighten Risk for Major Bone Fractures

Important assessment tool found to underestimate the risk for fracture in patients on psychiatric medication.

Maternal Antidepressant Use Tied to Autism

In a major study, published yesterday in JAMA Pediatrics, the use of SSRI antidepressants during pregnancy was found to increase the risk of autism spectrum disorder (ASD) by 87-percent. Previous studies reveal that more than 13-percent of women currently use SSRI antidepressants during pregnancy.

“Overprescribing of Drugs for Adult ADHD Causing ‘Trail of Misuse, Addiction and Death'”

An investigative report finds that the over-prescription of ADHD drugs is causing “a trail of misuse, addiction, and death.” “At morgues in Florida, a...

Study Finds Excess Pills Prescribed for Post-Operative Pain

Researchers find that patients are prescribed more pills than necessary after common surgical procedures

Study Finds the Spice Curcumin Fights Depression

The study finds that curcumin may be as efficacious as antidepressant medications, particularly for atypical depression

SSRI Exposure in Pregnancy Alters Fetal Neurodevelopment

Alterations in gray matter and white matter development found in infants of mothers taking SSRI antidepressants during pregnancy.

“New Psychiatric DNA Testing Is Unproven Ground”

NBC News reports that "Genetic tests to identify the most effective psychiatry drugs are the hot new thing in the race to create personalized treatments based on people's DNA.” An investigation by the New England Center for Investigative Reporting, however, found that these new tests are based on small studies conducted by device manufacturers, and those with financial conflicts on interest.

“Psychiatric Drugs Killing More Users than Heroin, Cocaine, Say Health Experts”

A groundbreaking article for The Province is “sounding the alarm over the heightened risk of death linked to the use of psychiatric drugs.” They report on...

Half of First-Episode Patients Respond to Antipsychotics

No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.

“B.C. Care Homes Provide Antidepressants Without Diagnoses”

New data reveals that the majority of care homes in British Columbia, Canada are giving out prescriptions for antidepressants and antipsychotics without a diagnosis....

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