New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”
A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”
New Data Show Lack of Efficacy for Antidepressants
An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.
Researchers Set the Record Straight on Controversial Zoloft Study
An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).
Researchers Expose Pharmaceutical Industry Misconduct and Corruption
Corruption of pharmaceutical industry sponsored clinical trials identified as a “major obstacle” facing evidence-based medicine.
Brain Scans Cannot Differentiate Between Mental Health Conditions
A new study analyzing over 21,000 participants found that differences in activation of brain regions in different psychological “disorders” may have been overestimated, and confirms that there is still no brain scan capable of diagnosing a mental health concern.
Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies
Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.
Researchers Question Link Between Genetics and Depression
A new study, published in the journal Molecular Psychiatry, found no link between genetics and the occurrence of depressive symptoms.
Safety Analysis Weighs Harms and Benefits of Antipsychotic Drugs
The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.
Multiple Researchers Examining the Same Data Find Very Different Results
A new study demonstrates how the choice of statistical techniques when examining data plays a large role in scientific outcomes.
German Psychologists Declare “the Drugs Don’t Work”
Jürgen Margraf and Silvia Schneider, both well-known psychologists at the University of Bochum in Germany, claim that psychotropic drugs are no solution to mental...
It is Time to Abandon the Candidate-Gene Approach to Depression
The candidate-gene approach to depression goes unsupported and is likely based on bad science, new research finds.
Lancet Psychiatry’s Controversial ADHD Study: Errors, Criticism, and Responses
Amid calls for a retraction, Lancet Psychiatry publishes articles criticizing the original finding and a response from the authors.
Researchers Ask, ‘Why Do Antidepressants Stop Working?’
An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.
Suicide Rates Rise While Antidepressant Use Climbs
Multiple media sources are reporting on new data from the CDC revealing a substantial increase in the suicide rate in the United States between 1999...
Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting
Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.
How Dissenting Voices are Silenced in Medicine
Researcher criticizes the many ways opposing viewpoints and dissenting voices are squashed in the field of medicine.
SNRIs Added to the List of Drugs with Potential Withdrawal Symptoms
New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.
Two-Thirds of Schizophrenia Patients Do Not Remit on Antipsychotics
A new analysis of antipsychotic treatment of schizophrenia (published in Schizophrenia Bulletin) has found that two-thirds of patients treated this way do not experience symptom remission.
Reanalysis of STAR*D Study Suggests Overestimation of Antidepressant Efficacy
Reanalysis of the original primary outcome measure in the STAR*D study suggests STAR*D findings inflate improvement on antidepressant medication and exclusion criteria in conventional clinical trials results in overestimation of antidepressant efficacy.
Publication Bias Inflates Perceived Efficacy of Depression Treatments, Study Finds
Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.
Biogen Pushes FDA to Approve Failed Alzheimer’s Drug
A new analysis, published in Lancet Neurology, demonstrates how Biogen is spinning results from two failed trials for a new Alzheimer's drug.
Study Examines the Difficulty of Withdrawing from Antidepressant Drugs
Correcting unnecessary long-term antidepressant use is difficult and met with apprehension by providers and service-users.
Researchers Find Inadequate Reporting of the Dangers of Ketamine Treatment for Depression
Researchers report that dangerous side effects are not being adequately reported in the trials of ketamine for depression.
Pervasive Industry Influence in Healthcare Sector Harms Patients
Experts across the globe point to the harms of drug companies’ influence on research, practice, and education in healthcare noting that it compromises patient care.
Most Psychology Research Does Not Generalize to the Individual
A new study claims that quantitative research in psychology is “worryingly imprecise” and that generalizations may be flawed and misleading.
