Suicide Rates Rise While Antidepressant Use Climbs
Multiple media sources are reporting on new data from the CDC revealing a substantial increase in the suicide rate in the United States between 1999...
New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”
A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”
Researchers Test Harms and Benefits of Long Term Antipsychotic Use
Researchers from the City College of New York and Columbia University published a study this month testing the hypothesis that people diagnosed with schizophrenia treated long-term with antipsychotic drugs have worse outcomes than patients with no exposure to these drugs. They concluded that there is not a sufficient evidence base for the standard practice of long-term use of antipsychotic medications.
Brain Scans Cannot Differentiate Between Mental Health Conditions
A new study analyzing over 21,000 participants found that differences in activation of brain regions in different psychological “disorders” may have been overestimated, and confirms that there is still no brain scan capable of diagnosing a mental health concern.
Lancet Psychiatry’s Controversial ADHD Study: Errors, Criticism, and Responses
Amid calls for a retraction, Lancet Psychiatry publishes articles criticizing the original finding and a response from the authors.
Multiple Researchers Examining the Same Data Find Very Different Results
A new study demonstrates how the choice of statistical techniques when examining data plays a large role in scientific outcomes.
Most Psychology Research Does Not Generalize to the Individual
A new study claims that quantitative research in psychology is “worryingly imprecise” and that generalizations may be flawed and misleading.
Researchers Expose Pharmaceutical Industry Misconduct and Corruption
Corruption of pharmaceutical industry sponsored clinical trials identified as a “major obstacle” facing evidence-based medicine.
Poor Evidence and Substantial Bias in Ritalin Studies
The authors of a large scale well-conducted systematic review of methylphenidate, also known as Ritalin, conclude that there is a lack of quality evidence for the drug’s effectiveness. Their research also revealed that Ritalin can cause sleep problems and decreased appetite in children.
It is Time to Abandon the Candidate-Gene Approach to Depression
The candidate-gene approach to depression goes unsupported and is likely based on bad science, new research finds.
Interview: Researchers Deconstruct Ghostwritten Industry Trial for Antidepressant
Researchers, Jon Jureidini, Jay Amsterdam and Leemon McHenry, have taken a closer look at the data from a randomized control trial of citalopram (Celexa) that was ghostwritten and then used by the manufacturers to support claims of the drug’s efficacy and safety in the treatment of child and adolescent depression. To get the background on this story, we connected with Dr. Leemon McHenry, an investigator in this study and a lecturer in philosophy at California State University, Northridge.
Researchers Question Link Between Genetics and Depression
A new study, published in the journal Molecular Psychiatry, found no link between genetics and the occurrence of depressive symptoms.
Ioannidis Questions Strength of Psychology and Neuroscience Literature
Last week, well-known Stanford scientist John Ioannidis and his colleague Denes Szucs released a new analysis online. They examined research published in eighteen prominent...
Two-Thirds of Schizophrenia Patients Do Not Remit on Antipsychotics
A new analysis of antipsychotic treatment of schizophrenia (published in Schizophrenia Bulletin) has found that two-thirds of patients treated this way do not experience symptom remission.
Publication Bias Inflates Perceived Efficacy of Depression Treatments, Study Finds
Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.
How Dissenting Voices are Silenced in Medicine
Researcher criticizes the many ways opposing viewpoints and dissenting voices are squashed in the field of medicine.
The P-Value Problem in Psychiatry
Stanford researcher writes that readers should check the effect size of results instead of looking at the p-value.
Study Examines the Difficulty of Withdrawing from Antidepressant Drugs
Correcting unnecessary long-term antidepressant use is difficult and met with apprehension by providers and service-users.
Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting
Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.
Review of Pediatric Antidepressant Studies Finds Evidence of Benefit Lacking
Review of pediatric antidepressant studies finds the vast majority are negative on primary outcomes and an increased risk for suicidality.
New Data Show Lack of Efficacy for Antidepressants
An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.
New Review of Antipsychotics for Schizophrenia Questions Evidence for Long Term Use
A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.
Poor and Foster Care Children More Likely to be Diagnosed and Treated with Psychiatric...
Study details Medicaid-insured birth cohort’s exposure to psychiatric medications and mental health services.
Brain Imaging Results Biased by Lack of Representative Data
What does "normal" brain development throughout childhood look like? It may depend on your demographics.
“Many Psychology Findings Not as Strong as Claimed, Study Says”
Today’s NY Times front page featured a story on the problem reproducibility poses for many psychology studies. The story is based on the results of a year-long study where the researchers found they were unable to reproduce 60 out of 100 studies published in three leading psychology journals. “The overall ‘effect size,’ a measure of the strength of a finding, dropped by about half across all of the studies.”