New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”

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A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”

Suicide Rates Rise While Antidepressant Use Climbs

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Multiple media sources are reporting on new data from the CDC revealing a substantial increase in the suicide rate in the United States between 1999...

Researchers Expose Pharmaceutical Industry Misconduct and Corruption

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Corruption of pharmaceutical industry sponsored clinical trials identified as a “major obstacle” facing evidence-based medicine.

Multiple Researchers Examining the Same Data Find Very Different Results

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A new study demonstrates how the choice of statistical techniques when examining data plays a large role in scientific outcomes.

Researchers Set the Record Straight on Controversial Zoloft Study

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An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).

New Data Show Lack of Efficacy for Antidepressants

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An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.

Brain Scans Cannot Differentiate Between Mental Health Conditions

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A new study analyzing over 21,000 participants found that differences in activation of brain regions in different psychological “disorders” may have been overestimated, and confirms that there is still no brain scan capable of diagnosing a mental health concern.

Interview: Researchers Deconstruct Ghostwritten Industry Trial for Antidepressant

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Researchers, Jon Jureidini, Jay Amsterdam and Leemon McHenry, have taken a closer look at the data from a randomized control trial of citalopram (Celexa) that was ghostwritten and then used by the manufacturers to support claims of the drug’s efficacy and safety in the treatment of child and adolescent depression. To get the background on this story, we connected with Dr. Leemon McHenry, an investigator in this study and a lecturer in philosophy at California State University, Northridge.

Lancet Psychiatry’s Controversial ADHD Study: Errors, Criticism, and Responses

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Amid calls for a retraction, Lancet Psychiatry publishes articles criticizing the original finding and a response from the authors.

German Psychologists Declare “the Drugs Don’t Work”

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Jürgen Margraf and Silvia Schneider, both well-known psychologists at the University of Bochum in Germany, claim that psychotropic drugs are no solution to mental...

It is Time to Abandon the Candidate-Gene Approach to Depression

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The candidate-gene approach to depression goes unsupported and is likely based on bad science, new research finds.

Pervasive Industry Influence in Healthcare Sector Harms Patients

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Experts across the globe point to the harms of drug companies’ influence on research, practice, and education in healthcare noting that it compromises patient care.

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

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Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

Poor Evidence and Substantial Bias in Ritalin Studies

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The authors of a large scale well-conducted systematic review of methylphenidate, also known as Ritalin, conclude that there is a lack of quality evidence for the drug’s effectiveness. Their research also revealed that Ritalin can cause sleep problems and decreased appetite in children.

Poor and Foster Care Children More Likely to be Diagnosed and Treated with Psychiatric...

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Study details Medicaid-insured birth cohort’s exposure to psychiatric medications and mental health services.

New Review of Antipsychotics for Schizophrenia Questions Evidence for Long Term Use

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A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.

Psychotherapy Effectiveness for Depression Inflated by Publication Bias

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While publication bias has been known to overestimate the efficacy of antidepressant treatments, a new study suggests that research on the use of psychotherapy in depression suffers from a similar bias.

How Dissenting Voices are Silenced in Medicine

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Researcher criticizes the many ways opposing viewpoints and dissenting voices are squashed in the field of medicine.

Publication Bias Inflates Perceived Efficacy of Depression Treatments, Study Finds

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Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.

Researchers Question Link Between Genetics and Depression

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A new study, published in the journal Molecular Psychiatry, found no link between genetics and the occurrence of depressive symptoms.

“Alarm and Disbelief” as New EU President Moves Regulation of Medicines to Industry Ministry

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The new President-elect of the European Union Jean-Claude Juncker has removed key responsibilities relating to health and medicines from the government Commissioner in charge...

Children Diagnosed with ADHD Younger are More Likely to get Multiple Medications

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New research demonstrates that children diagnosed with ADHD at younger ages are more likely than those diagnosed later to receive multiple medications within five years of their diagnosis.

Researchers Ask, ‘Why Do Antidepressants Stop Working?’

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An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.

Ioannidis Questions Strength of Psychology and Neuroscience Literature

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Last week, well-known Stanford scientist John Ioannidis and his colleague Denes Szucs released a new analysis online. They examined research published in eighteen prominent...

Editorial Takes On Conflicts of Interest and Propaganda in Psychiatry

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In a scathing editorial in this month’s Psychotherapy and Psychosomatics, Dr. Giovanni Fava takes aim at prominent medical experts who have downplayed the role...