Upon Further Review

A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.

A new article in BMJ Evidence-Based Medicine addresses common misinterpretations of the efficacy research on antidepressants.

Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.

Review of pediatric antidepressant studies finds the vast majority are negative on primary outcomes and an increased risk for suicidality.

Dr. Johnathan Shedler recently published a paper critiquing how the term “evidence-based” is being used in the field of psychotherapy.

Researchers argue for plurality and diversity among psychotherapy approaches and question the perceived superiority of Cognitive Behavioral Therapy (CBT).

A new study, published online by the Open Science Foundation, suggests that questionable research practices (QRPs) are prevalent in the fields of ecology and evolution.

With increasing evidence that psychiatric drugs do more harm than good over the long term, the field of psychiatry often seems focused on sifting through the mounds of research data it has collected, eager to at last sit up and cry, here’s a shiny speck of gold! Our drugs do work! One recently published study on withdrawal of antipsychotics tells of long-term benefits. A second tells of long-term harm. Which one is convincing?

In a new study, researchers examined 29 popular introduction to psychology textbooks and found that almost 80% included misinformation about intelligence.

A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”

Due to the thickness of the scalp and skull, transcranial electrical stimulation (TES) is incapable of targeting networks of neurons in the brain.

In a new study, researchers argue that correlational studies may not sufficiently account for alternative explanations, and offer suggestions for mitigating this danger.

Review of a new mixed depression guideline reveals financial bias of guideline developers and lack of evidence supporting recommendations for prescribing of antipsychotics.

New research shows that more connected and well-known researchers are more likely to be published, even when they receive negative reviews.

Corruption of pharmaceutical industry sponsored clinical trials identified as a “major obstacle” facing evidence-based medicine.

Scientists at the Yale Collaboration for Research Integrity and Transparency (CRIT) published a new policy paper this month criticizing the current state of biomedical research and calling for improved transparency in research methods.

A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.

Dr. Madhukar Trivedi and colleagues find that the SSRI sertraline does not reduce depressive symptoms any more than placebo in people with Chronic Kidney Disease.

A new study conducted by Jeffrey Vittengl at Truman University has found that taking antidepressant medications resulted in more severe depression symptoms after nine years.

What does "normal" brain development throughout childhood look like? It may depend on your demographics.

Researchers examined the dearth of support for Electroconvulsive therapy (ECT) for depressive symptoms in light of studies detailing the associated risks.

Researchers report that dangerous side effects are not being adequately reported in the trials of ketamine for depression.

Surveyed doctors overestimate pharmacological effects of antidepressants and underestimate placebo effects.

Evidence of duplicate publishing in articles analyzing data from clinical trials testing second-generation antipsychotics for depression

A review of academic textbooks finds that they often leave out effect sizes and molecular genetics findings, both of which suggest minimal impact of genetics on ADHD. Instead, textbooks focus on overblown conclusions from behavioral studies.