New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmfulā€

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A new study published in Frontiers in Psychiatry concludes that ā€œantidepressants are largely ineffective and potentially harmful.ā€

Antidepressants Do Not Prevent Suicides, May Increase Risk

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When the CDC released data revealing an increasing suicide rate in the US, some experts, speaking to major media outlets, speculated that the increase...

Multiple Researchers Examining the Same Data Find Very Different Results

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A new study demonstrates how the choice of statistical techniques when examining data plays a large role in scientific outcomes.

Psychiatry Defends Its Antipsychotics: A Case Study of Institutional Corruption

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Jeffrey LIeberman and colleagues have published a paper in the American Journal of Psychiatry stating that there is no evidence that psychiatric drugs cause long-term harm, and that the evidence shows that these drugs provide a great benefit to patients. A close examination of their review reveals that it is a classic example of institutional corruption, which was meant to protect guild interests.

No Brain Connectivity Differences Between Autism, ADHD, and ā€œTypical Developmentā€

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Neuroscience researchers find no differences in brain connectivity between children with diagnoses of autism, ADHD, and those with no diagnoses.

Mental Health Concerns Not ā€œBrain Disorders,ā€ Say Researchers

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The latest issue of the journal Behavioral and Brain Sciences features several prominent researchers arguing that mental health concerns are not ā€œbrain disorders.ā€

Study Finds ADHD Drugs Alter Developing Brain

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A new study, published in the JAMA Psychiatry, investigates the effect of stimulant ā€˜ADHDā€™ drugs on the brains of children and young adults. The...

Lancet Psychiatryā€™s Controversial ADHD Study: Errors, Criticism, and Responses

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Amid calls for a retraction, Lancet Psychiatry publishes articles criticizing the original finding and a response from the authors.

What is the Evidence for Empirically Supported Treatments in Psychology?

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New meta-scientific review questions the evidence for the gold standard psychotherapies and empirically supported treatments.

It is Time to Abandon the Candidate-Gene Approach to Depression

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The candidate-gene approach to depression goes unsupported and is likely based on bad science, new research finds.

Positive Antidepressant Study ā€œMisleadingā€ and ā€œErroneous”

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An analysis of last yearā€™s positive finding in The Lancet about antidepressant efficacy shows errors, obfuscations, and misrepresentations.

Brain Scans Cannot Differentiate Between Mental Health Conditions

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A new study analyzing over 21,000 participants found that differences in activation of brain regions in different psychological ā€œdisordersā€ may have been overestimated, and confirms that there is still no brain scan capable of diagnosing a mental health concern.

New Data Show Lack of Efficacy for Antidepressants

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An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.

German Psychologists Declare ā€œthe Drugs Donā€™t Workā€

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JĆ¼rgen Margraf and Silvia Schneider, both well-known psychologists at the University of Bochum in Germany, claim that psychotropic drugs are no solution to mental...

Interview: Researchers Deconstruct Ghostwritten Industry Trial for Antidepressant

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Researchers, Jon Jureidini, Jay Amsterdam and Leemon McHenry, have taken a closer look at the data from a randomized control trial of citalopram (Celexa) that was ghostwritten and then used by the manufacturers to support claims of the drugā€™s efficacy and safety in the treatment of child and adolescent depression. To get the background on this story, we connected with Dr. Leemon McHenry, an investigator in this study and a lecturer in philosophy at California State University, Northridge.

Rigorous Study Finds Antidepressants Worsen Long-Term Outcomes

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A new study conducted by Jeffrey Vittengl at Truman University has found that taking antidepressant medications resulted in more severe depression symptoms after nine years.

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

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Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

New Review of Antipsychotics for Schizophrenia Questions Evidence for Long Term Use

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A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.

Researchers Question ā€œGold Standardā€ Status of Cognitive Behavioral Therapy

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Researchers argue for plurality and diversity among psychotherapy approaches and question the perceived superiority of Cognitive Behavioral Therapy (CBT).

Researchers: ā€œAntidepressants Should Not be Used for Adults with Major Depressive Disorderā€

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A new review, published in BMJ Evidence-Based Medicine, concludes that antidepressants should not be used as the risks outweigh evidence for benefits.

Researchers Expose Pharmaceutical Industry Misconduct and Corruption

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Corruption of pharmaceutical industry sponsored clinical trials identified as a ā€œmajor obstacleā€ facing evidence-based medicine.

Review of Pediatric Antidepressant Studies Finds Evidence of Benefit Lacking

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Review of pediatric antidepressant studies finds the vast majority are negative on primary outcomes and an increased risk for suicidality.

ā€˜Do Antidepressants Work?ā€™ is the Wrong Question

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ā€œThis research points to the inadequacy of asking the simple question: ā€˜Do antidepressants work?ā€™ Instead, the value or otherwise of antidepressants needs to be understood in the context of the diversity of experience and the particular meaning they hold in peopleā€™s lives.ā€

Ioannidis Questions Strength of Psychology and Neuroscience Literature

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Last week, well-known Stanford scientist John Ioannidis and his colleague Denes Szucs released a new analysis online. They examined research published in eighteen prominent...

Brain Imaging Results Biased by Lack of Representative Data

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What does "normal" brain development throughout childhood look like? It may depend on your demographics.