Antidepressants Do Not Prevent Suicides, May Increase Risk

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When the CDC released data revealing an increasing suicide rate in the US, some experts, speaking to major media outlets, speculated that the increase...

Psychiatry Defends Its Antipsychotics: A Case Study of Institutional Corruption

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Jeffrey LIeberman and colleagues have published a paper in the American Journal of Psychiatry stating that there is no evidence that psychiatric drugs cause long-term harm, and that the evidence shows that these drugs provide a great benefit to patients. A close examination of their review reveals that it is a classic example of institutional corruption, which was meant to protect guild interests.

Researchers Set the Record Straight on Controversial Zoloft Study

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An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).

Mental Health Concerns Not “Brain Disorders,” Say Researchers

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The latest issue of the journal Behavioral and Brain Sciences features several prominent researchers arguing that mental health concerns are not “brain disorders.”

Rigorous Study Finds Antidepressants Worsen Long-Term Outcomes

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A new study conducted by Jeffrey Vittengl at Truman University has found that taking antidepressant medications resulted in more severe depression symptoms after nine years.

New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”

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A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”

Multiple Researchers Examining the Same Data Find Very Different Results

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A new study demonstrates how the choice of statistical techniques when examining data plays a large role in scientific outcomes.

Researchers Expose Pharmaceutical Industry Misconduct and Corruption

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Corruption of pharmaceutical industry sponsored clinical trials identified as a “major obstacle” facing evidence-based medicine.

What is the Evidence for Empirically Supported Treatments in Psychology?

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New meta-scientific review questions the evidence for the gold standard psychotherapies and empirically supported treatments.

Researchers: “Antidepressants Should Not be Used for Adults with Major Depressive Disorder”

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A new review, published in BMJ Evidence-Based Medicine, concludes that antidepressants should not be used as the risks outweigh evidence for benefits.

No Brain Connectivity Differences Between Autism, ADHD, and “Typical Development”

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Neuroscience researchers find no differences in brain connectivity between children with diagnoses of autism, ADHD, and those with no diagnoses.

Study Finds ADHD Drugs Alter Developing Brain

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A new study, published in the JAMA Psychiatry, investigates the effect of stimulant ‘ADHD’ drugs on the brains of children and young adults. The...

Interview: Researchers Deconstruct Ghostwritten Industry Trial for Antidepressant

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Researchers, Jon Jureidini, Jay Amsterdam and Leemon McHenry, have taken a closer look at the data from a randomized control trial of citalopram (Celexa) that was ghostwritten and then used by the manufacturers to support claims of the drug’s efficacy and safety in the treatment of child and adolescent depression. To get the background on this story, we connected with Dr. Leemon McHenry, an investigator in this study and a lecturer in philosophy at California State University, Northridge.

Brain Scans Cannot Differentiate Between Mental Health Conditions

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A new study analyzing over 21,000 participants found that differences in activation of brain regions in different psychological “disorders” may have been overestimated, and confirms that there is still no brain scan capable of diagnosing a mental health concern.

Review Finds FDA Approval of Digital Antipsychotic Misguided

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The approval of the digital antipsychotic may open the door for more pharmaceutical company profits without evidence of benefits to patients.

New Data Show Lack of Efficacy for Antidepressants

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An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.

How Dissenting Voices are Silenced in Medicine

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Researcher criticizes the many ways opposing viewpoints and dissenting voices are squashed in the field of medicine.

Researchers Question Link Between Genetics and Depression

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A new study, published in the journal Molecular Psychiatry, found no link between genetics and the occurrence of depressive symptoms.

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

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Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

German Psychologists Declare “the Drugs Don’t Work”

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Jürgen Margraf and Silvia Schneider, both well-known psychologists at the University of Bochum in Germany, claim that psychotropic drugs are no solution to mental...

Zoloft Does Not Improve Depression, Even in Severe Cases, Study Finds

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Despite their finding, the researchers suggest that SSRIs be given to people who do not meet criteria for depression or anxiety.

Publication Bias Inflates Perceived Efficacy of Depression Treatments, Study Finds

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Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.

Reanalysis of STAR*D Study Suggests Overestimation of Antidepressant Efficacy

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Reanalysis of the original primary outcome measure in the STAR*D study suggests STAR*D findings inflate improvement on antidepressant medication and exclusion criteria in conventional clinical trials results in overestimation of antidepressant efficacy.

Researchers Question “Gold Standard” Status of Cognitive Behavioral Therapy

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Researchers argue for plurality and diversity among psychotherapy approaches and question the perceived superiority of Cognitive Behavioral Therapy (CBT).

It is Time to Abandon the Candidate-Gene Approach to Depression

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The candidate-gene approach to depression goes unsupported and is likely based on bad science, new research finds.