Antipsychotics

New research published in the July issue of The Journal of Clinical Psychiatry found that the use of mood stabilizers, antipsychotics, antidepressants, and hypnotics during pregnancy is associated with increased health risks to the infant.

New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”

Only one out eight patients, out of 108 with tardive dyskinesia, recovered from the disorder in an Emory University Movement Disorders Clinic study. The...

A double-blind, randomized, placebo-controlled study comparing outcomes from risperidone, cognitive therapy, and supportive therapy in a cohort of 115 at-risk young adults over a...

A new review of antipsychotic trials conducted over the last 24 years finds that the placebo response rate is steadily increasing, and drug response is decreasing.

Clinicians are following best practice guidelines only half of the time when giving antipsychotic medications to children, and following FDA-approved indications only one-fourth of the time.

The August issue of the British Journal of Psychiatry offers an editorial stating that, as "mental health services appear to have overestimated the strength...

The digital pill Abilify MyCite, which is now being introduced into the market, foretells of a future where such technology is used to monitor the behavior, location and "medication compliance" of a person 24 hours a day.

“Live, healthy babies are the most common outcome following the use of antipsychotic medication in pregnancy,” conclude Australian researchers in a study that was...

A large review and meta-analysis of 167 studies across 60 years dissects placebo-controlled randomized controlled trials of antipsychotic drugs.

A study published today in the American Medical Association's journal JAMA Psychiatry reports that patients whose antipsychotic treatment was reduced or discontinued (DR) experienced a recovery...

Outcomes were worse for all, with young people on combination therapy twice as likely to experience rehospitalization or death by suicide than those on antidepressants alone.

A partnership designed to decrease antipsychotic use in elderly patients may have led to increased use of medications with even worse risk/benefit profiles.

Antipsychotics appear to be too often prescribed to curb aggressive impulses in children and youth, rather than to treat psychosis or any other clinically indicated conditions.

Use of second-generation antipsychotics (SGA) alongside other medications is growing rapidly among youth who are less impaired, according to a study published online in...

This month’s issue of JAMA Psychiatry ran an editorial commenting on recent research revealing that the majority of youth prescribed antipsychotics have not been diagnosed with a mental disorder.

In a study of 597 outpatients who were perceived as likely nonadherers to oral antipsychotic interventions, Spanish researchers found that relapse was lower in...

A new study published this month in the journal Neuron identifies the mechanism by which antipsychotic drugs can induce parkinsonism, a condition involving movement...

"Many patients with first-episode psychosis receive medications that do not comply with recommended guidelines for first-episode treatment," states a National Institute of Mental Health...

A new study published in JAMA Psychiatry connects antipsychotics with damage to the brain in multiple areas.

Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.

Dutch researchers write in the Journal of Clinical Psychopharmacology that, in a prospective study of 7415 persons with diagnoses of schizophrenia, use of a first-generation...

A new attempt to study the neurological effects of long-term exposure to antipsychotics uses healthy volunteers on minimal doses for 15 days.

A recent RCT showed that vitamin B6 is as effective as propranolol for the treatment of akathisia.

A comprehensive review indicates that children exposed to antipsychotics in the womb face an increased risk of ADHD and developmental delays.