Antipsychotics

Researchers in London and Spain, in a prospective, randomized, study of long-term (3 year) effects of first- and second-generation antipsychotics on neurocognition in 79...

In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.

One-third of adults with an intellectual or developmental disability are dispensed antipsychotics, despite having no existing psychiatric diagnosis.

A large longitudinal study finds once more that being prescribed antipsychotics significantly increases the risk of diabetes.

A new study in JAMA Neurology finds that the use of antipsychotic drugs more than doubled the risk of death in patients with Parkinson’s...

Researchers from the City College of New York and Columbia University published a study this month testing the hypothesis that people diagnosed with schizophrenia treated long-term with antipsychotic drugs have worse outcomes than patients with no exposure to these drugs. They concluded that there is not a sufficient evidence base for the standard practice of long-term use of antipsychotic medications.

The popular smoking cessation drug Chantix is the medication that most frequently makes people feel suicidal or homicidal, according to figures gathered by the...

Martin Harrow's study tracing the effects of antipsychotics on 139 schizophrenia (SZ) and mood-disordered patients over 20 years, just published in Psychological Medicine, finds...

In a systematic literature review, researchers from Canada and Japan found that the antipsychotic aripiprazole (Abilify) was significantly and causally related to increased increased...

Researchers in Barcelona, Spain retrospectively reviewed the use of antipsychotics in 117,811 patients, of whom 9,855 were given combinations of antipsychotics and 13,763 were...

A large observational study published in CNS Drugs sheds light on serious adverse effects of the ‘gold standard’ antipsychotic Clozapine.

Researchers from Tufts and Harvard find in a review of 233 medical charts of psychiatrically hospitalized youth at three points in time (1991, 1998...

Annals of Pharmacotherapy reports in a study of patients undergoing mechanical ventilation that 39% were given antipsychotic medication to prevent or treat delirium despite...

Researchers reveal the limitations and misleading interpretations of two recent studies that claim to demonstrate that long-term antipsychotic use leads to better outcomes.

Jeffrey LIeberman and colleagues have published a paper in the American Journal of Psychiatry stating that there is no evidence that psychiatric drugs cause long-term harm, and that the evidence shows that these drugs provide a great benefit to patients. A close examination of their review reveals that it is a classic example of institutional corruption, which was meant to protect guild interests.

In a study of 720 consecutive hospital admissions in a specific catchment area from 1991 to 2005, researchers found that there was no difference...

Research undermines the prolonged use of antipsychotics in schizophrenia treatment, suggesting improved social functioning and quality of life with discontinuation.

20-year follow-up study finds that after four years, patients not prescribed antipsychotics have significantly better work functioning.

Researchers in Singapore find that antipsychotic medications are associated with changes to colonic architecture, which could result in difficult colonoscopy and increased colonoscopy-related risks....

The digital pill Abilify MyCite, which is now being introduced into the market, foretells of a future where such technology is used to monitor the behavior, location and "medication compliance" of a person 24 hours a day.

Finnish reseachers report in Schizophrenia Research that antipsychotic use is associated with cognitive and memory impairments. The University of Oulu team studied forty people...

Writing in the Journal of Clinical Psychiatry, researchers from the Health Economics Resource Center studied the effects of long-acting injectable risperidone (Consta) on 369 patients...

People who take antipsychotic medications experience many side effects which have "major disruptive impact on their lives," according to research in the Journal of Mental Health Nursing.

New research counters the long-held assumption that a longer duration of untreated psychosis is associated with worse outcomes.

Results of a large government-funded study call into question current drug heavy approaches to treating people diagnosed with schizophrenia. The study, which the New York Times called “by far the most rigorous trial to date conducted in the United States,” found that patients who received smaller doses of antipsychotic drugs with individual talk therapy, family training, and support for employment and education had a greater reduction in symptoms as well as increases in quality of life, and participation in work and school than those receiving the current standard of care.