Rise of Antipsychotics in Children
Researchers at Johns Hopkins explore the use of antipsychotics in children, finding a dramatic rise in off-label prescribing with little oversight or research into...
Reducing Antipsychotic Use May Improve Health for People with Mental Health Diagnoses
A new study offers radical solutions for improving the cardiovascular health of people with mental health diagnoses: reducing antipsychotic prescriptions..
Pentagon Was Warned Off Antipsychotic for PTSD
Despite 2004 clinical guidelines issued by the Veterans' Administration that "there is insufficient evidence to recommend atypical antipsychotics for the treatment of PTSD," ...
Outcome Reporting Bias in Antipsychotic Medication Trials
A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.
More than Half of UK Antipsychotic Prescribing is Not for Authorized Conditions
More than half of the prescriptions for antipsychotic drugs in the UK are being issued "off-label" to treat conditions other than those for which the drugs are approved, according to a large study published in the British Medical Journal Open. Researchers also found significantly higher levels of prescribing of the medications to poorer people.
Researchers Struggle as Placebos Becoming More Effective & Antipsychotics Losing Power
Since the 1960s, the positive response rates to antipsychotic medications have been dropping steadily, according to a meta-analysis published in JAMA Psychiatry by Columbia...
2nd-Generation Antipsychotics Cause Extrapyramidal Side Effects as Much as 1st-Generation
According to researchers from Yale and the U.K., the improvements in extrapyramidal side effects expected from 2nd-generation antipsychotics has not been realized, while the...
Less-impaired Youth Using Antipsychotics with Other Medications More Often
Use of second-generation antipsychotics (SGA) alongside other medications is growing rapidly among youth who are less impaired, according to a study published online in...
PTSD and Psychiatric Medication Linked to Dementia in Older Veterans
Veterans diagnosed with PTSD and taking SSRIs, novel antidepressants, or atypical antipsychotics are more likely to develop dementia.
Elderly Patients Who Stop Antipsychotics Have Better Outcomes
Older adults are often prescribed antipsychotics off-label for behavioral control in the hospital. But there’s no evidence for antipsychotics helping, and a great deal of evidence of harm.
Antipsychotics Too Often Used to Dampen Aggression in Kids, Not Treat Psychosis
Antipsychotics appear to be too often prescribed to curb aggressive impulses in children and youth, rather than to treat psychosis or any other clinically indicated conditions.
Antipsychotics Not Helpful for Anorexia
A review of all research on the use of antipsychotics for the treatment of anorexia nervosa found no demonstrable efficacy in terms of body...
Abilify Can Worsen Psychosis & Aggression
In a systematic literature review, researchers from Canada and Japan found that the antipsychotic aripiprazole (Abilify) was significantly and causally related to increased increased...
Barriers to Shared Decision Making in the Prescription of Antipsychotics
Researchers push for a renewed focus on true shared decision-making for patients diagnosed with psychosis.
Study Suggests Long-Term Antipsychotic Use May Result in Poorer Cognitive Functioning
Association found between long-term antipsychotic use and poorer performance on cognitive tasks in adults diagnosed with ‘schizophrenia.’
Antipsychotic Use in Nursing Homes Causing Many Adverse Effects in Elderly
A literature review found that the extensive off-label use of antipsychotic medications in nursing homes is causing many adverse effects and providing limited benefits.
Antipsychotics Triple the Risk of Diabetes in Children and Youth
Researchers from Vanderbilt and Columbia Universities and the FDA find that, through a retrospective cohort study of 28,858 patients of the Tennessee Medicaid program...
How Exercise Can Help With First Episode Psychosis
New study examines the experiences of people utilizing an exercise program following a first-episode psychosis.
Better Outcomes Off Medication for Those Recovered from First-Episode Schizophrenia
A new study has found that of 10 people who were fully recovered from their first episode of schizophrenia (FES), those not taking antipsychotics did better in terms of cognitive, social, and role functioning—and reached full recovery more quickly.
Reduction/Discontinuation of Antipsychotics Produces Higher Long-Term Recovery
A study published today in the American Medical Association's journal JAMA Psychiatry reports that patients whose antipsychotic treatment was reduced or discontinued (DR) experienced a recovery...
More Evidence That Antipsychotics Shrink the Brain
European researchers who reviewed 43 imaging studies of first-episode psychosis found evidence that antipsychotics cause a decrease in gray matter volumes in the brain....
Mental Health Nurses Do Not Routinely Assess for Effects of Antipsychotic Medications
Researchers believe that side-effect monitoring is critical because of the increase in the use of antipsychotics
Antipsychotics are Poor Sleep Aids
Research from Australia shows that "remained pervasive" in 70% of a sample of 83 patients medicated with antipsychotics and other medications, and concludes that...
A Guide to Minimal Use of Neuroleptics
This guide, by psychiatrists Volkmar Aderhold and Peter Stastny, provides a comprehensive review of antipsychotics and an evidence-based rationale for avoiding their use in first-episode psychosis, and for minimizing their long-term use.
Increasing Use of Antipsychotics for Disruptive Behavior in Children
Canadian researchers systematically reviewed all randomized controlled trials of second-generation antipsychotics (SGAs) and placebo in the treatment of disruptive behavior disorders in children, finding...
