Neuropsychological Tests Reveal Consequences of Polypharmacy
Neuropsychological assessments reveal the cognitive, occupational, and social impact of polypharmacy in psychiatry.
Youth Antipsychotic Use Linked to Increased Risk of Death within Five Years
Those aged 18-24 had an increased risk of death within five years on doses above 100 mg chlorpromazine equivalents.
Many Teens Start Misusing Stimulants By Age 13
An equal percentage of young people will start misusing ADHD-related and other stimulant drugs for the first time at age 13 as will start at age 20.
Recovery Rate Six Times Higher For Those Who Stop Antipsychotics Within Two Years
People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.
Antidepressants Not Superior to Psychotherapy for Severe Depression
On Wednesday, JAMA Psychiatry released a meta-analysis comparing the results of cognitive-behavioral therapy and antidepressant medication in severely depressed populations. Currently, many practice guidelines suggest that antidepressants be used over psychotherapy for major depressive disorder. The analysis, however, found that “patients with more severe depression were no more likely to require medications to improve than patients with less severe depression.”
Ritalin Causes Long-Lasting Change in Prefrontal Neurons
Drexel University researchers found that methylphenidate (Ritalin) administered to juvenile rats produced significant depressive effects on pyramidal neurons. The authors conclude that "the juvenile...
Understanding the Neurobiology of Post-SSRI Sexual Dysfunction
Post-SSRI sexual dysfunction (PSSD) may be a common adverse effect of antidepressants. Researchers are now attempting to understand the neurobiology behind it.
Antidepressants Overprescribed to Post-Menopausal Women Despite Risks
A new study reveals that antidepressants, commonly prescribed to post-menopausal women, may increase risks of falls, cognitive decline, and cardiovascular issues, raising questions about their overuse in this population.
Prenatal Exposure to SSRIs Significantly Increases Autism & Developmental Delays
Research on 966 mother-child pairs from the Childhood Autism Risks from Genetics and the Environment (CHARGE) Study finds that prenatal SSRI exposure was nearly 3...
Antidepressants & Sexual Function
Two studies of the effects of antidepressants on sexual function - one on the relative effects across classes of antidepressants on men, the other...
Researchers Expose Pharmaceutical Industry Misconduct and Corruption
Corruption of pharmaceutical industry sponsored clinical trials identified as a “major obstacle” facing evidence-based medicine.
Information on PRN Medication Practices is Lacking
The authors of an article in Journal of Psychosocial Nursing reviewed the literature on psychotropic PRN medications in order to respond to a request to...
Fluoxetine in Adolescence Raises Sensitivity to Stress in Adults
Research on neurochemicals associated with moods in mice and rats finds that, while less depression-like behavior was observed in those receiving fluoxetine (Prozac) administration...
New Clinical Guidelines on Deprescribing Benzodiazepines
New guidelines recommend deprescribing benzodiazepine receptor agonists for adults.
Antidepressants Worsen Rapid Cycling in Bipolar Depression
-SSRI antidepressant medications contribute to a significant worsening of emotional "rapid cycling" in patients diagnosed with bipolar disorder.
Antipsychotics Increase Risk of Dementia; New Research Illuminates Why
In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.
More Evidence Antidepressants Might Induce Sexual Dysfunction Even After Stopping Them
A retrospective study in the Journal of Clinical Psychiatry examined cases of people who suffered sexual dysfunction that endured even after stopping taking SSRI antidepressants.
Alarming Report on Antidepressant Side Effects
Drawing on analysis of data from websites such as Paxilprogress.org, ehealthforum.com, depression forums.org, about.com, medhelp.org, drugLib.com, topic.com and survivingantidepressants.org, researchers from the University of...
Antidepressants Have No Effect On Bipolar Depression
In a review of 68 articles published between 2005 and 2011, Israeli researchers found that most well-controlled studies failed to show a significant effect of...
Review Links Antipsychotics with Risk for Heart Attacks
A systematic review published this week in the British Journal of Clinical Pharmacology found that patients taking antipsychotic drugs were at nearly twice the risk...
Acute Respiratory Failure More Likely in COPD Patients Prescribed Antipsychotics
Researchers recommend that healthcare professionals be vigilant regarding the signs of respiratory failure among patients with COPD who are receiving antipsychotics, especially during the initial treatment phase.
Does Active Placebo Response Explain Antidepressant Results?
A new study investigated whether participants guessing if they have an antidepressant or placebo affects response rates.
U.K.’s Guardian Survey: “Your Experiences of Antidepressants”
The U.K. newspaper The Guardian asked readers of five newspapers in the U.K., Germany, France, Spain and Italy to talk about their experiences of...
Antidepressant Withdrawal Misdiagnosed as Functional Disorder
Adverse physiological symptoms of antidepressant withdrawal are regularly mistaken to be other problems to the detriment of the patient.
Turmeric as Effective as Prozac, With no Side-Effects
A randomized, controlled study by the Department of Pharmacology of Government Medical College in Bhavnagar, Gujarat, India found that in a study of 60...
