Mental Health Staff Reluctant to Support Service Users in Tapering Antipsychotics, Study Finds

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Study reveals schizophrenia patients find little support from mental health staff in reducing side effects-heavy drugs.

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

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Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

Antidepressant Withdrawal Linked to Suicide Attempt in Case Study

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Researchers suggest that antidepressant withdrawal can be a possible precipitant of suicide.

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

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Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

Tapering Strips Help People Stop Using Antidepressants, Study Finds

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A new study by Peter Groot and Jim van Os investigated whether tapering strips can help people stop using antidepressants.

Researchers Document Protracted Withdrawal from Antidepressants

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Protracted Withdrawal Syndrome characterized by long-term adverse experiences after coming off of antidepressants.

Researchers Provide Guidance for Reducing and Stopping Psychiatric Drugs

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New guidance on how to taper and discontinue from psychiatric drugs from leading researchers Mark Horowitz and David Taylor.

SNRIs Added to the List of Drugs with Potential Withdrawal Symptoms

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New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

Many Service Users Interested in Decreasing Antipsychotic Use with Professional Help

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New research examines service user attitudes on discontinuing and reducing antipsychotic drugs.

“Treatment Resistant” Schizophrenia Strongly Linked to Dopamine Supersensitivity

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Over 70% of schizophrenia patients who are "treatment resistant" have apparently developed dopamine supersensitivity psychosis from long-term use of antipsychotic medications.

Withdrawal Symptoms Cloud Findings of Antidepressant “Relapse” Trial

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Leading researchers point out that a new antidepressant study in NEJM failed to account for withdrawal symptoms, casting doubt on the results.

Danish Study Finds Better 10-year Outcomes in Patients Off Antipsychotics

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Study finds that 74% of patients with a psychotic disorder off antipsychotics at end of 10 years are in remission.

Common Benzodiazepine Sedatives May Induce Aggression

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Benzodiazepine medications that are commonly used for calming or sedating people can sometimes apparently cause violent or aggressive responses in some people, according to...
Girl, looking confused, holding pill bottle

Official Guidelines on Antidepressant Discontinuation Fail Practitioners and Patients

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A review of clinical practice guidelines for antidepressant discontinuation from across the English-speaking world reveals major pitfalls.

Listening to the Patient Voice: The Antidepressant Withdrawal Experience

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Patient advocates join with researchers and service users to present first-hand experiences of antidepressant withdrawal.

Antidepressants Actually Reduce Serotonin Levels

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Common scientific beliefs about serotonin levels in depression and how antidepressants act on the brain appear to be completely backwards.

“Relapse” in Antidepressant Trials Likely Caused by Sudden Withdrawal

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A new study investigates how antidepressant withdrawal effects often get confounded with depression relapse in clinical trials.

What Do Antidepressants in Drinking Water Do to Birds?

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Ever higher levels of pharmaceutical drugs are turning up in drinking water supplies, and an op-ed in the UK Mirror discusses a study that...

Antipsychotics During Pregnancy Linked to Infant Problems

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“Live, healthy babies are the most common outcome following the use of antipsychotic medication in pregnancy,” conclude Australian researchers in a study that was...

Differentiation of SSRI and Benzo Dependence/Withdrawal “Not Rational”

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Researchers from the Cochrane Center and University of Copenhagen in Denmark, publishing in the May issue of Addiction, "explore the rationale for claiming that...

Sudden Antipsychotic Withdrawal—Not Low Dose—Leads to Relapse

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A new article in Lancet Psychiatry debunks past studies claiming that those on low doses of antipsychotics are more likely to relapse.

Antidepressant Caused Six-fold Artery Plaque Build-up in Monkeys

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Zoloft caused up to six-fold increases in build-up of atherosclerosis plaque in the coronary arteries of monkeys.

Keys to Successful Discontinuation of Antipsychotic Medication

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Qualitative study finds that both internal resources and systemic factors play a role in antipsychotic discontinuation outcomes.

Global Survey Leads to New Recommendations for Deprescribing Psychiatric Drugs

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Growing rates of long-term psychiatric drug prescriptions and documented issues with withdrawal demonstrate a need for safe deprescribing practices.

Antidepressants Linked to Doubling of Failure of Dental Implants

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People who take SSRI antidepressants are twice as likely to have their dental implants fail, according to McGill University researchers. In a press release,...