Friday, August 7, 2020

MIA News Archives

SNRIs Added to the List of Drugs with Potential Withdrawal Symptoms

New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

New Study Explores Approaches to Discontinuing Antidepressants

Psychiatrist and psychologist outline pharmacological and psychotherapeutic strategies for discontinuing antidepressants.

Psychological Interventions Can Help When Tapering Off Antidepressants

Meta-analysis of antidepressant tapering finds CBT and MBCT can aid in tapering, but limited studies met inclusion criteria.

Replacing Pain with Pain: Hazards of Antidepressant Use for Chronic Pain Relief

The paradox of relieving chronic pain with an antidepressant (and a new set of symptoms).

Autism, Antidepressants, and Pregnancy: The Basics

This month, the seventh study and eighth study came out on the topic of antidepressant exposure during pregnancy and autism.  And these studies showed, as essentially all of the others have, that antidepressant use during pregnancy (principally with selective serotonin reuptake inhibitors or SSRIs) is associated with autism in the exposed children. With so many children being diagnosed with autism and so many women taking antidepressants during pregnancy, everyone wants to know: are these things (the antidepressants) associated with autism or not?  Quite frankly no one has the time to read through all eight scientific papers (and dozens more animal and basic science studies) to understand this important area, so I will do my best to briefly summarize it here.

New Antidepressant Shows Little Benefit, Significant Risks

Patient Drug News advises avoiding use of the antidepressant Vortioxetine (also called Brintellix or Trintellix), because the most recent evidence from the FDA shows...

Antidepressant Use Climbs as Patients Find it Difficult to Discontinue

Findings point to the role of withdrawal symptoms and prescriber practices in long-term antidepressant use.

New Clinical Guidelines on Deprescribing Benzodiazepines

New guidelines recommend deprescribing benzodiazepine receptor agonists for adults.

More Psychological Supports Needed to Manage Antidepressant Discontinuation

Study reviews psychological interventions for antidepressant discontinuation.

Antipsychotic-induced Sexual Dysfunction Underreported

Researchers found some antipsychotics to be worse than others for causing sexual dysfunction.

Social Support Improves Antipsychotic Discontinuation, Study Finds

A new study explores how people manage to discontinue antipsychotic medication and examines how social supports may improve outcomes.

More Evidence Antidepressants Might Induce Sexual Dysfunction Even After Stopping Them

A retrospective study in the Journal of Clinical Psychiatry examined cases of people who suffered sexual dysfunction that endured even after stopping taking SSRI antidepressants.

Report Calls For Policy Changes In Response To Dependence and Withdrawal From Prescribed Drugs

Statistics from the UK reveal that prescriptions for painkillers and antidepressants continue to rise despite concerns over dependence and debilitating withdrawal effects. The British Medical Association (BMA) Board of Science has released a report that acknowledges changes to medical practice, research and policy necessary for addressing the dependence and withdrawal effects of benzodiazepines, opioids, and antidepressants.

Prenatal Antidepressant Exposure Raises Risk to Newborn of Pulmonary Hypertension

Researchers from Canada find the risk of persistent pulmonary hypertension of the newborn is increased for infants exposed to SSRIs in late pregnancy. Results...

Some Common Psychiatric Medications Associated With Pneumonia

Pneumonia cases in the elderly are strongly associated with use of anticholinergic medications, including benzodiazepines and tricyclic antidepressants.

Neuroleptic Drugs and Violence

Neuroleptic Drugs and Violence by Catherine Clarke SRN, SCM, MSSCH, MBChA. and Jan Evans MCSP. Grad Dip Phys.

British Medical Association Takes On Prescription Drug Dependence

Last year the British Medical Association (BMA) released a report on dependence and withdrawal from prescription drugs including benzodiazepines, z-drugs, opioids, and antidepressants. Now,...

Different Antipsychotics Have Different Effects on Brain Volume

First generation antipsychotics seem to cause general brain volume loss, while second generation antipsychotics seem to both increase and decrease the thickness of different parts of the brain.

New Research on Patient-Centered Deprescribing for Antipsychotics

Researchers review the risks and benefits of deprescribing from antipsychotic drugs and advocate for a patient-centered approach to tapering.

When Switching Antipsychotics, No Difference Between Immediate and Gradual Discontinuation

Review study compares outcomes of gradual vs. immediate antipsychotic discontinuation when switching from one drug to another.

Antidepressants Linked to Doubling of Failure of Dental Implants

People who take SSRI antidepressants are twice as likely to have their dental implants fail, according to McGill University researchers. In a press release,...

Cognitive Function Improved by Reducing Antipsychotics

A 28-week randomized controlled study by researchers in Japan, Canada and the United States finds that a 50% reduction of risperidone or olanzapine significantly...

Prescribing Benzodiazepines As-Needed Leads to Abuse

A new study reported on in Medscape, examined risk factors for misuse of benzodiazepines (drugs such as Xanax, Ativan, and Klonopin). The researchers found that patients who had been prescribed the medication on an as-needed basis were more likely to end up abusing it than those who had been prescribed a standing dose.

More Discussion of Antidepressant Withdrawal Effects

-Forensic psychiatrist Andrew Shepherd reviews a recent study on withdrawal effects from coming off antidepressant drugs.

Over One Thousand Boys Grew Breasts “Probably” Caused By Common Psychiatric Medication

According to an ex-chief of the FDA, Johnson & Johnson knew long before it started warning people that Risperdal could cause boys to grow breasts.

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