Peter Simons covers in detail a new systematic review that debunks the widely popularized myth of low serotonin in depression, the “chemical imbalance theory.”
Researchers argue that we need a paradigm shift away from the biomedical model of mental illness to one informed by political action and common sense.
A study in JAMA Neurology finds that antidepressants do not reduce depression symptoms more than placebo in patients recovering from a stroke.
A meta-analysis published last month showed that psychotherapy has an enduring effect on depression—in contrast to depression pills.
In May 2021, Cochrane published a network meta-analysis of depression pills for children. The abstract is misleading and reads like drug company marketing.
Evolutionary theorists suggest that antidepressants interfere with the adaptive function of depression and propose a test of this theory.
A researcher and service user Stevie Lewis recounts her own experience with antidepressant withdrawal and what she wishes her doctors knew.
Researchers find a lack of current literature on safe, effective ways to manage antidepressant withdrawal and make suggestions for future research.
An analysis of FDA adverse event reports related to esketamine shows the potential for negative effects such as suicidal and self-injurious ideation.
The promotion of SSRI antidepressant use began with the pharmaceutical industry and occurs despite evidence that these drugs are harmful, not helpful, in children and adolescents.
The medicalisation of our emotional lives has led to a horrific cultural shift in which we, and our children, have become alienated from and suspicious of our emotions, chipping away at our natural resilience.
A new study offers promising results for psilocybin-assisted psychotherapy for depression.
Researchers review a new synthesis of the existing evidence and conclude that the harms of antidepressants outweigh any benefits.
This piece is the second of a two-part essay about suicide, diagnosis, what doesn't help, and what does help. This part is about barriers to seeking help and about the ways we actually can be of help to people who are considering suicide.
This piece is the first of a two-part essay about suicide, diagnosis, what doesn't help, and what does help. This part is about suicide, diagnosis, and some of what fails to help.
A new review of strategies to support both patients and practitioners through the process of discontinuing antidepressants.
Trials of antidepressants for relapse prevention are confounded by withdrawal effects caused by the drugs.
It seems more and more common for people who consider themselves mental health advocates to make the argument that “mental illness is like physical illness.” Have you heard this “depression is like diabetes” tactic? I have a hard time seeing how this is advocating for those in emotional distress.