Tag: Depression

Cultural psychiatrist G. Eric Jarvis discusses religion and mental health, the social determinants of psychosis, and how coercive treatment can deepen mistrust in psychiatric care.

The Accord program in Arlington Massachusetts will provide a test of whether an intensive ketogenic program, when combined with drug-tapering support, can lead to robust recovery over the long term, with diminished use--or no ongoing use--of psychiatric medications.

Response and remission rates failed to beat placebo in a new Harvard meta-analysis, throwing the inflammation hypothesis into question.

Researchers found that for many doctors, renewing antidepressant prescriptions feels safer and faster than helping people taper, and that most current interventions fail to address the pressures driving that choice.

The authors call for a paradigm shift in mental health care that emphasizes empathy, context, and alternatives to medication as first-line treatments for depression.

A reanalysis of STAR*D finds no support for the theorized subgroup of patients who do well on antidepressants.

A new study, published in Molecular Psychiatry, investigates the prevalence and typical characteristics of antidepressant withdrawal syndrome (AWS) through analyzing available research. Researchers found...

A new study reveals that antidepressants, commonly prescribed to post-menopausal women, may increase risks of falls, cognitive decline, and cardiovascular issues, raising questions about their overuse in this population.

While the study can’t confirm causality, it does contradict the notion that antidepressants reduce suicide at the population level.

Outcomes were worse for all, with young people on combination therapy twice as likely to experience rehospitalization or death by suicide than those on antidepressants alone.

More than two and a half years later, I’m still processing my grief, still picturing our happiness and innocence as kids, and still acknowledging our struggles and pain.

Researchers find that SSRIs increase suicide attempts up to age 24, and have no preventative effect at any age, even for those at high risk of suicide.

For those with severe depression, inpatient CBT was effective but the adding antidepressants did not improve treatment outcomes.

The initial study, which has been used to promote antidepressants, employed outcome switching to hide poor results.

In a study of people with borderline personality disorder, only ADHD stimulants were associated with a decrease in suicide.

Genetic testing may help reduce the length of time people experience the harmful effects of antidepressant drugs, but it is not helpful for predicting efficacy.

A new Cochrane review details the lack of evidence for antidepressants in the treatment of chronic pain.

New study finds polypharmacy for 73% of older adults on antidepressants, with 56% at risk of harmful drug interactions.

Peter Simons covers in detail a new systematic review that debunks the widely popularized myth of low serotonin in depression, the “chemical imbalance theory.”

Ketamine treatment, which was being hailed as a ‘miracle cure’, backfired so spectacularly that it very nearly cost me my life.

Researchers argue that we need a paradigm shift away from the biomedical model of mental illness to one informed by political action and common sense.

A study in JAMA Neurology finds that antidepressants do not reduce depression symptoms more than placebo in patients recovering from a stroke.

A meta-analysis published last month showed that psychotherapy has an enduring effect on depression—in contrast to depression pills.

In May 2021, Cochrane published a network meta-analysis of depression pills for children. The abstract is misleading and reads like drug company marketing.

Evolutionary theorists suggest that antidepressants interfere with the adaptive function of depression and propose a test of this theory.