Outcomes were worse for all, with young people on combination therapy twice as likely to experience rehospitalization or death by suicide than those on antidepressants alone.
More than two and a half years later, I’m still processing my grief, still picturing our happiness and innocence as kids, and still acknowledging our struggles and pain.
Researchers find that SSRIs increase suicide attempts up to age 24, and have no preventative effect at any age, even for those at high risk of suicide.
For those with severe depression, inpatient CBT was effective but the adding antidepressants did not improve treatment outcomes.
In a study of people with borderline personality disorder, only ADHD stimulants were associated with a decrease in suicide.
Genetic testing may help reduce the length of time people experience the harmful effects of antidepressant drugs, but it is not helpful for predicting efficacy.
A new Cochrane review details the lack of evidence for antidepressants in the treatment of chronic pain.
New study finds polypharmacy for 73% of older adults on antidepressants, with 56% at risk of harmful drug interactions.
Peter Simons covers in detail a new systematic review that debunks the widely popularized myth of low serotonin in depression, the “chemical imbalance theory.”
Researchers argue that we need a paradigm shift away from the biomedical model of mental illness to one informed by political action and common sense.
A study in JAMA Neurology finds that antidepressants do not reduce depression symptoms more than placebo in patients recovering from a stroke.
A meta-analysis published last month showed that psychotherapy has an enduring effect on depression—in contrast to depression pills.
In May 2021, Cochrane published a network meta-analysis of depression pills for children. The abstract is misleading and reads like drug company marketing.
Evolutionary theorists suggest that antidepressants interfere with the adaptive function of depression and propose a test of this theory.
A researcher and service user Stevie Lewis recounts her own experience with antidepressant withdrawal and what she wishes her doctors knew.
Researchers find a lack of current literature on safe, effective ways to manage antidepressant withdrawal and make suggestions for future research.
An analysis of FDA adverse event reports related to esketamine shows the potential for negative effects such as suicidal and self-injurious ideation.
The promotion of SSRI antidepressant use began with the pharmaceutical industry and occurs despite evidence that these drugs are harmful, not helpful, in children and adolescents.
The medicalisation of our emotional lives has led to a horrific cultural shift in which we, and our children, have become alienated from and suspicious of our emotions, chipping away at our natural resilience.
A new study offers promising results for psilocybin-assisted psychotherapy for depression.