Tag: Depression

Initial Trial of Ayahuasca for Depression Shows Promising Results

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Ayahuasca found to be effective in treating moderate to severe depression in low-income population.

Researchers Set the Record Straight on Controversial Zoloft Study

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An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).

Ketamine for Harmful Drinking: A Look at the Data

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New research contends that ketamine can reduce problematic alcohol use but does the data support the claims?

How Antidepressants Shape Young Women’s Sense of Self

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Young women’s narratives indicate ways antidepressants have shaped their sense of self.

No Matter Which Measure You Use, Antidepressants Aren’t That Effective

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Researchers compared the efficacy of antidepressants using different rating scales and found them to be no different—just slightly better than placebo, and not meeting the criteria for clinical significance.

Psychotherapy Less Effective for People in Poverty and Those on Antidepressants

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A new study finds poorer depression and anxiety outcomes in psychotherapy for people in economically deprived neighborhoods and those on antidepressants.

Increased Antidepressant Use Does Not Decrease Depression Prevalence in Older Adults

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The use of antidepressants has risen quickly among older adults but the rate of depressive symptoms in this population has not declined as a result.

Training Health Workers in Therapy Leads to Improvements and Less Medication...

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A Nigerian study finds that more than three-quarters of patients improved, even when only 13% were prescribed medication.

Researchers Challenge Evidence for Antidepressants in Youth

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Researchers shed light on the precarious nature of evidence from efficacy trials of antidepressant medication to treat symptoms of major depressive disorder in children and adolescents.

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

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A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

Smartphones, Loneliness, and Depression in Teens

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New study finds that smartphone use may precede experiences of loneliness and depressive symptoms among older teens according to longitudinal analysis.

“Flimsy Evidence” for Esketamine as Depression Treatment

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A new article documents the “flimsy evidence” behind the recent FDA approval of the party drug esketamine for the treatment of depression.

Discrimination Leads to Mental Distress for Gender Diverse People

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Researchers seek to identify adaptive coping responses to discrimination for the transgender and gender diverse community.

Non-Gender Affirmative Treatment Detrimental to Mental Health

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Gender identity conversion efforts impact psychological distress and lifetime suicidality in transgender people.

Clinical Trials Show Antidepressants “Not Beneficial in the Long Term”

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Clinical trials also consistently fail to measure and report long-term harmful effects.

Clinical Guidelines for Depression Need Urgent Revision

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A coalition of 35 health organizations expressed serious concerns that the NICE guideline for adult depression may cause clinical harm—they demand “full and proper” revisions.

Researchers: “Antidepressants Should Not be Used for Adults with Major Depressive...

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A new review, published in BMJ Evidence-Based Medicine, concludes that antidepressants should not be used as the risks outweigh evidence for benefits.

Decontextualized Depression and PTSD Diagnoses Fail Indigenous Communities

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A case analysis of an American Indian woman illustrates how the DSM diagnostic criteria misrepresent the lives of indigenous people.

Zoloft Does Not Improve Depression, Even in Severe Cases, Study Finds

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Despite their finding, the researchers suggest that SSRIs be given to people who do not meet criteria for depression or anxiety.

Antidepressant Use Associated With More Violent Suicide Attempts

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A new study found that taking an antidepressant medication was associated with a heightened risk of suicide using violent means.

Antidepressant Use Does Not Prevent Suicide, Study Finds

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A new study has found that antidepressants are ineffective for reducing suicide attempts. Researchers report that the risk of suicide is particularly high in the first month after starting an antidepressant.

Therapy Gets More Effective Over Time While Antidepressants Decrease in Effectiveness

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New review of long-term depression data finds psychotherapy more effective over time whereas antidepressants decrease in effectiveness.

Guidelines Recommending Antidepressants “in Contradiction with the Current Evidence”

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Researchers critique the German S3 guidelines for depression promoting antidepressants.

William James’s Letter to His Depressed Daughter

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If you discover that your child has been experiencing a bout with depression, what wise words might you share? Brilliant psychologist William James was forced to address this issue himself when his 13-year-old daughter, Peg, began to struggle with melancholy. I present his long, thoughtful reply for your consideration.

Explaining Depression Biologically Increases Prognostic Pessimism

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Psychoeducation that explains depression in biological terms increases prognostic pessimism, perceived stability of depression, and openness to psychiatric medication.