New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”

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A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”

Study 329: The Data Wars Cross the Rubicon

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It can be difficult to pinpoint transitions. The Rubicon that led from a Medical Republic to a Pharmaceutical Empire was crossed in 1962 with the passage of the Amendments to the Food and Drugs Act. This act put in place an apparatus of controlled trials, prescription-only status and disease indications that laid the basis for a global pharmaceutical hegemony, although the drift to Empire could still have been stopped at this point.

When Psychiatric Medications Cause Psychiatric Symptoms

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Dr. Yolande Lucire, a psychiatrist from Australia, recently published a paper about the iatrogenic effects of psychiatric drugs.

Identifying Psychiatric Drugs Leading to Emergency Room Visits

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More than ten-percent of adults in the United States are currently prescribed at least one psychiatric medication but there is currently a lack of research on the prevalence of adverse drug events (ADEs) associated with these prescriptions outside of clinical trials.

Training Nursing Home Staff in Understanding Needs Can Reduce Antipsychotic Use

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A new study published in JAMA Internal Medicine, the largest study of its kind, has shown it is possible to reduce the use of antipsychotics in nursing homes, by engaging their staff in a training program designed to target residents’ strengths and their unmet needs.

“New ‘Smart’ Drugs Tell Doctor You’re Not Taking Them”

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The Washington Examiner reports that the manufacturer of the antipsychotic Abilify is seeking FDA approval for new digitized pills that would alert doctors if patients fail to take their drugs on schedule.

Researchers Question Link Between Genetics and Depression

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A new study, published in the journal Molecular Psychiatry, found no link between genetics and the occurrence of depressive symptoms.

Benzodiazepine Prescriptions in Older Adults Used in Rural and Low Income Areas

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Benzodiazepine prescription practices may be in response to an epidemic of distress, rather than being used to treat specific mental health diagnoses.

Prescription Stimulant Use is Associated with Earlier Onset of Psychosis

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Individuals diagnosed with psychotic disorders have an earlier onset of psychosis if they have previously been exposed to prescription stimulants, according to new research currently in press in the Journal of Psychiatric Research.

Researchers Expose Pharmaceutical Industry Misconduct and Corruption

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Corruption of pharmaceutical industry sponsored clinical trials identified as a “major obstacle” facing evidence-based medicine.

The Inherent Unreliability of the ADHD Label

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I imagine that everybody on this side of the issue knows by now that the eminent psychiatrist Jeffrey Lieberman, MD, Chief Psychiatrist at Columbia, and past President of the APA, called Robert Whitaker "a menace to society." The grounds for Dr. Lieberman's vituperation were that Robert had dared to challenge some of psychiatry's most sacred tenets! But in all the furor, it was largely ignored that in the same interview Dr. Lieberman had said something else that warrants additional discussion.

Video: More Harm than Good Conference on Psychiatric Drugs

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On September 18th the one day "More Harm than Good Conference" brought together many of the leaders of the critical psychiatry movement. While the event has passed, the video and slides from the conference have been made available on the council for evidence-based psychiatry website.

Researcher Acknowledges His Mistakes in Understanding Schizophrenia

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Sir Robin Murray, a professor at the Institute of Psychiatry, Psychology, and Neuroscience in London, states that he ignored social factors that contribute to ‘schizophrenia’ for too long. He also reports that he neglected the negative effects antipsychotic medication has on the brain.

Antipsychotics Associated with High Risk of Death in Children

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A new study has found that children and adolescents taking a high dose of antipsychotics are almost twice as likely to die of any cause than children on other types of medications.

Clinical Trials Show Antidepressants “Not Beneficial in the Long Term”

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Clinical trials also consistently fail to measure and report long-term harmful effects.

Researchers Pressure Psychiatric Journal to Retract Misleading Celexa Study

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In 2004, the American Psychiatric Association published a paper supporting the use of the antidepressant citalopram (Celexa) in children and teens. After reanalyzing the...

Study of Online Antidepressant Forums Reveals Long Lasting Withdrawal Effects

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Effects of discontinuing SSRIs and SNRIs reported on an online forum indicate significant and long-lasting withdrawal symptoms.

New Study Examines Successful Discontinuation of Antipsychotics

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A new study to be published in the next issue of Schizophrenia Research examines patients suffering from a first-episode of psychosis who stop taking any antipsychotic drugs. The researchers attempt to identify variables that can serve as predictors of the successful discontinuation of antipsychotics. They find, for example, that those who discontinue the drugs have, on average, the same outcomes as those who stay on them, and that those who have better social integration are more likely to discontinue without relapse.

Unsafe Use of Sleep Drug Zolpidem is Common

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Three out of four users of the sedative, zolpidem (brand name Ambien), do not follow FDA recommendations to reduce risk.

The Dopamine Hypothesis of Schizophrenia – Version III

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The Division of Clinical Psychology of the British Psychological Society published a paper titled Understanding Psychosis and Schizophrenia. The central theme of the paper is that the condition known as psychosis is better understood as a response to adverse life events rather than as a symptom of neurological pathology. The paper was wide-ranging and insightful and, predictably, drew support from most of us on this side of the issue and criticism from psychiatry.  Section 12 of the paper is headed "Medication" and under the subheading "Key Points" you'll find this quote: "[Antipsychotic] drugs appear to have a general rather than a specific effect: there is little evidence that they are correcting an underlying biochemical abnormality."

Researchers Confirm That Relative Age Impacts ADHD Diagnosis

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The youngest children in a class are more likely to receive an ADHD diagnosis than their peers.

Lancet Editorial Points to “Trouble with Psychiatry Trials”

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While clinical trials make up the “bedrock of evidence-based medicine” in other specialties, psychiatry faces a number of both ethical and scientific problems related to its use of randomized control trials. According to a new editorial in The Lancet Psychiatry, the field of psychiatry research has particular problems with ethical issues in recruitment, inaccurate classification systems, and controversial placebo comparisons, and then, once the studies are finished, it often remains unclear what the “outcomes actually mean for people’s lives.”

Antidepressant Use Linked to Longer, More Frequent Psychiatric Rehospitalization

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New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.

“Psychiatric Drug—Not Antibiotic—Messes with Gut Microbes, Spurs Obesity”

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In a series of experiments in mice, researchers found that the drug risperidone alters gut microbes, which in turn profoundly influence metabolism, weight, and overall health.

Researchers Find Inadequate Reporting of the Dangers of Ketamine Treatment for Depression

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Researchers report that dangerous side effects are not being adequately reported in the trials of ketamine for depression.