About 1 in 100 Children Treated with Ritalin Experience a Serious Adverse Event

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A recent Cochrane review has found that serious adverse events occur for about 1% of children and adolescents treated with Ritalin.

Most People with Common ‘Mental Disorders’ Get Better Without Treatment, Study Finds

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A new study suggests that most people diagnosed with depressive, anxiety, and substance abuse disorders recover without treatment within a year of diagnosis. “This...

Clinical Trials Show Antidepressants “Not Beneficial in the Long Term”

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Clinical trials also consistently fail to measure and report long-term harmful effects.

“In Surprise Decision, FDA Blocks Crucial Cognitive Claim for Takeda’s Brintellix”

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Takeda and Lundbeck had prepared to advertise that their latest antidepressant Brintellix (Vortioxetine) could give patients a cognitive boost and help them think and...

Teen Brain Develops Differently in Bipolar Disorder, When Medicated

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The brains of adolescents diagnosed with bipolar disorder develop differently than the brains of teens without the disorder, according to a study in Biological...

“Federal Judge Declines to Toss Paxil Suicide Case, Setting GSK up for September Trial”

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Wendy Dolin sued GSK after her husband committed suicide after taking a generic version of Paxil. The US District Court has declined GSK’s motions...

SNRIs Added to the List of Drugs with Potential Withdrawal Symptoms

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New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

The Evidence-Based Mind of Psychiatry on Display

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The writings of Pies and his colleagues, I believe, provide a compelling case study of cognitive dissonance. Cognitive dissonance arises when people are presented with information that creates conflicted psychological states, challenging some belief they hold dear, and people typically resolve dissonant states by sifting through information in ways that protect their self-esteem and their financial interests. It is easy to see that process operating here.

The Case Against Antipsychotics

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This review of the scientific literature, stretching across six decades, makes the case that antipsychotics, over the long-term, do more harm than good. The drugs lower recovery rates and worsen functional outcomes over longer periods of time.

Antidepressants Not a ‘One Size Fits All’ Solution, Researchers Find

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The largest ever study of the thoughts and reactions of antidepressant users reveals that many people have vastly different understandings and experiences of the...

“Study Finds Risks for Teens of Mothers Who Took Certain Antidepressants”

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“Adolescents whose mothers took certain antidepressants while pregnant with them are more than four times as likely to become depressed by age 15, compared with...

Does Active Placebo Response Explain Antidepressant Results?

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A new study investigated whether participants guessing if they have an antidepressant or placebo affects response rates.

In Chronic Patients, Antipsychotics Have Limited Efficacy in Reducing Symptoms

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A large review and meta-analysis of 167 studies across 60 years dissects placebo-controlled randomized controlled trials of antipsychotic drugs.

Psychotherapy Effectiveness for Depression Inflated by Publication Bias

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While publication bias has been known to overestimate the efficacy of antidepressant treatments, a new study suggests that research on the use of psychotherapy in depression suffers from a similar bias.

Researcher Challenges Clinical Effectiveness of Antidepressants

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A new article in BMJ Evidence-Based Medicine addresses common misinterpretations of the efficacy research on antidepressants.

Rigorous Study Finds Antidepressants Worsen Long-Term Outcomes

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A new study conducted by Jeffrey Vittengl at Truman University has found that taking antidepressant medications resulted in more severe depression symptoms after nine years.

Animal Study Supports Influence of Probiotics on Resilience to Stress

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Researchers experimenting on mice found that Lactobacillus—the probiotic commonly found in yogurt—may help reduce depressive symptoms in reaction to chronic stressors. But human studies have found mixed results.

Therapy Gets More Effective Over Time While Antidepressants Decrease in Effectiveness

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New review of long-term depression data finds psychotherapy more effective over time whereas antidepressants decrease in effectiveness.

Summary of Recent Antidepressant Meta-Analyses

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On his own website, clinical psychologist Kenneth Pope has summarized 60 meta-analyses of antidepressants published between 2013-2015. The studies contain information on antidepressants “uses,...

Race and Class Affect Teacher Perceptions of ADHD Medication Use

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Study uncovers teachers’ attitudes surrounding ADHD medication use and examines the influence of race and social class on teacher beliefs.

iPad Use Before Surgery as Effective as Sedatives for Children

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A group of French doctors presented a new study in the area of pediatric anesthesiology at this year’s World Congress of Anaesthesiologists in Hong...

3 Facts All Parents Should Know About ADHD Stimulant Drugs

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Medicating children for a host of mental disorders has become very popular in some parts of the USA. More than 8 million kids from 6 months to 17 years of age are on pharmaceutical drugs in this wonderful country. We lead the world in drugging youth for behavioral, cognitive and attention issues. We are once again #1. But I would like to share with parents as well as adults working with children a few not so readily available facts related to medicating kids for behavior issues.

Ethical Failings in Experimental Drug Safety Trials

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Leading human subjects ethics researcher questions exploitation of uninsured minorities in experimental drug trials.

German Psychologists Declare “the Drugs Don’t Work”

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Jürgen Margraf and Silvia Schneider, both well-known psychologists at the University of Bochum in Germany, claim that psychotropic drugs are no solution to mental...

SSRI Exposure in Pregnancy Alters Fetal Neurodevelopment

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Alterations in gray matter and white matter development found in infants of mothers taking SSRI antidepressants during pregnancy.